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Section Highlights View all Bioinformatics and Genomics articles

Genome-wide identification of CBF genes and their responses to cold acclimation in Taraxacum kok-saghyz
"The study using non-model plants provides novel findings about cold stress tolerance that is different from the model plant Arabidopsis."
Koji Mikami, Handling Editor
DeepNC: a framework for drug-target interaction prediction with graph neural networks
"Deep learning-based drug-target interaction prediction is a significant topic."
Yuriy Orlov, Handling Editor
COVID-19 mortality is associated with pre-existing impaired innate immunity in health conditions
D. Gareth Evans, Handling Editor
Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules
"Important observations were made related to the perturbed SARS-CoV-2 variants peptide presentation by HLA molecules"
Vladimir Uversky, Handling Editor
A systematic review on cough sound analysis for Covid-19 diagnosis and screening: is my cough sound COVID-19?
"I believe this is the first systematic review on analyzing the cough sounds toward COVID-19 diagnosis. The study includes all possible literature adopting PRISMA guidelines."
Sivaramakrishnan Rajaraman, Handling Editor
PipeCoV: a pipeline for SARS-CoV-2 genome assembly, annotation and variant identification
"The paper "PipeCoV: A Pipeline for SARS-CoV-2 Genome Assembly, Annotation and Variant Identification" presents a well-established SARS-CoV-2 pipeline with a lower content of Ns and higher genome coverage when compared to the Wuhan reference. The pipeline also provides a variant report available at https://github.com/alvesrco/pipecov"
Marisa Nicolás, Handling Editor
A hybrid feature selection algorithm and its application in bioinformatics
"A hybrid feature selection algorithm has been proposed using the bio-information. The methodology refines the feature of the data with a great potential in helping scientists cross-discipline to identify novel targets and biomarkers for cancer research."
Qichun Zhang, Handling Editor
An issue of concern: unique truncated ORF8 protein variants of SARS-CoV-2
"The findings may shed additional light on the pathogenicity of SARS-CoV-2. It should be an important resource for the research community."
Jun Chen, Handling Editor
High-performance pipeline for MutMap and QTL-seq
"it is a nice contribution to the field."
Jun Chen, Section Editor
Identification of potential biomarkers of vascular calcification using bioinformatics analysis and validation in vivo
"Interesting results with therapeutical implications of modulated genes related to vascular calcification (VC) are indicated."
Maria Cristina Albertini, Handling Editor
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