Bioinformatics and Genomics

Article commentary

Computational fluid dynamics modelling of left valvular heart diseases during atrial fibrillation

Editor rating: 7 / 10

Ebba Brakenhielm –– This work provides a novel integrated model for how valvular stenosis (aortic vs mitral) influence hemodynamics in the setting of atrial fibrillation.
Detection of methylation, acetylation and glycosylation of protein residues by monitoring 13C chemical-shift changes: A quantum-chemical study

Editor rating: 7 / 10

Rüdiger Ettrich –– I think the article might nicely advertise how computational predictions can complement experimental data in a useful way. This makes the article interesting not only for the NMR community but to protein chemists in general.
Love the one you’re with: replicate viral adaptations converge on the same phenotypic change

Editor rating: 7 / 10

Alexander Mikheyev –– It is a bit inconclusive, but deals with important questions in biology.
Virus wars: using one virus to block the spread of another

Editor rating: 7 / 10

Tomas Perez-Acle –– This interesting work proposes a combination of experimental procedures and mathematical modeling to provide new ways to manage infectious diseases.
On causality of extreme events

Editor rating: 7 / 10

Christopher Lortie –– broad implications on philosophy of science and interpretation.
DICOM for quantitative imaging biomarker development: a standards based approach to sharing clinical data and structured PET/CT analysis results in head and neck cancer research

Editor rating: 8 / 10

Henkjan Huisman –– Medical images are useless for research unless annotations can be added. This paper describes an elegant open source frame work to do this.
Testing the potential of a ribosomal 16S marker for DNA metabarcoding of insects

Editor rating: 8 / 10

Alexander Mikheyev –– This could be a very generally useful tool.
Estimating risks of importation and local transmission of Zika virus infection

Editor rating: 8 / 10

Giovanni Benelli –– Predicting Zika virus outbreaks is a crucial challenge in parasitology and public health sciences. This research is timely and of great interest for a wide readership.
Sequencing 16S rRNA gene fragments using the PacBio SMRT DNA sequencing system

Editor rating: 7 / 10

Christine Josenhans –– platform comparison for NGS high throughput sequencing; implementation of novel platform based on PacBio SMRT sequencing for 16S amplicon sequencing. These technologies are of prime importance in the ever-growing field of microbiome/microbiota research
A molecular classification of human mesenchymal stromal cells

Editor rating: 7 / 10

Eric Schirmer –– For many cell fate decisions differences in gene expression or proteomic data from multiple studies raises a question of what are the most appropriate molecular markers. The approach in this article of large-scale data mining is a reasonable one that can be applied more widely and provides a good set of markers for mesenchymal cells.

Discussing these articles

212 days ago
Virus wars: using one virus to block the spread of another https://t.co/oLyUZU7z25

My article 'A molecular classification of human mesenchymal stromal cells' published in PeerJ has 2,562 views and 8 citations! I love #OpenAccess @thePeerJ

My article was published 1 year ago today in #OpenAccess journal @thePeerJ https://t.co/76F5Ee2ryJ // 1 year old soo cute XD cc @aloctavodia

Nature World News: "Virus Wars: Using "Good" Viral Agents to Combat Killer Viruses"
http://www.natureworldnews.com/articles/24839/20160706/virus-wars-using-good-viral-agents-combat-killer-viruses.htm

Engadget: "Researchers want to block HIV with a 'therapeutic' virus"
https://www.engadget.com/2016/07/05/researchers-want-to-block-hiv-with-a-therapeutic-virus/

The Japan Times: "New study estimates transmission risk of Zika virus in Japan at 16% for rest of year"
http://www.japantimes.co.jp/news/2016/04/05/national/science-health/new-study-estimates-transmission-risk-zika-virus-japan-16-rest-year/#.VwQGC_krKUk