28 March 2024

Identification of WRKY gene family in Dioscorea opposita Thunb. reveals that DoWRKY71 enhanced the tolerance to cold and ABA stress

"This is good piece of work and will enhance about our knowledge about the WRKY family and their role in abiotic stress tolerance."

Kashmir Singh, Handling Editor

27 March 2024

The clinical association of programmed death-1/PD-L1 axis, myeloid derived suppressor cells subsets and regulatory T cells in peripheral blood of stable COPD patients

Ramcés Falfán-Valencia, Handling Editor

15 March 2024

Exploring the antioxidant potential of chalcogen-indolizines throughout in vitro assays

"The authors' study has certain reference value for the development of related drugs."

Xin Zhang, Handling Editor

14 March 2024

Chigno/CG11180 and SUMO are Chinmo-interacting proteins with a role in Drosophila testes somatic support cells

"This paper identifies new players in Drosphila testes stem cell differentiation by identifying Chimno interacting partners."

Judith Yanowitz, Handling Editor

1 March 2024

Bimetallic nanoparticles and biochar produced by Adansonia Digitata shell and their effect against tomato pathogenic fungi

"The manuscript addresses a relevant issue, the search for new compounds with antifungal activities."

Héctor Mora-Montes, Handling Editor

29 February 2024

Molecular cloning and characterization of farnesyl diphosphate synthase from Rosa rugosa Thunb associated with salinity stress

Mahmood-ur- Rahman, Handling Editor

29 February 2024

Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction

"The discussed work highlights the global concern of obesity as a public health epidemic, emphasizing its association with chronic inflammation and related diseases. The research focuses on a novel compound, Cyy-287, reporting on its inhibitory effect on high-fat diet-induced inflammation and tissue damage in mice. The study delves into the molecular mechanisms, revealing that Cyy-287 acts by inhibiting NF-κB and MAPK signaling pathways, activating AMPK signaling, and suppressing liver lipid synthesis. The findings suggest that Cyy-287 has therapeutic potential for mitigating obesity-induced cardiac and hepatic damage. The limitations are acknowledged, and future studies are proposed to deepen the understanding of Cyy-287's mechanisms and effects. The work is significant for researchers and clinicians interested in developing treatments for obesity-related complications."

Sonia Oliveira, Section Editor

27 February 2024

A review on the traditional uses, nutritive importance, pharmacognostic features, phytochemicals, and pharmacology of Momordica cymbalaria Hook F

"Herbal medicines remain a relevant field that not only provides functional phytopharmaceutical molecules for the pharmaceutical industry but also in other industries such as cosmetics or food. The challenges with standardization and quality control can be overcome when comprehensive reviews are performed on a plant source."

Sonia Oliveira, Handling Editor

27 February 2024

Retrospective study and implementation of a low-cost LAMP-turbidimetric assay for screening α⁰-thalassemia (SEA deletion): preventing and controlling Hb Bart’s hydrops fetalis syndrome in Thailand

"Shows the application of a fast real time molecular test kit in a clinical setting"

Efe Sezgin, Handling Editor

26 February 2024

Multiscale transport and 4D time-lapse imaging in precision-cut liver slices (PCLS)

"This paper describes a method for tracking nuclear location, cell volume, and tissue volume after osmotic perturbation of liver tissue. This is relevant to tissue and organ cryopreservation, as well as a better understanding of the biology and biomechanics of liver tissue."

Tokuko Haraguchi, Handling Editor