Background: Ozempic is widely discussed on social media, and YouTube videos may influence expectations about benefits, risks, and safe use. However, content quality varies, and popularity does not necessarily reflect educational value. The study aims to evaluate educational themes, information quality, reliability, title–content alignment, and usefulness of YouTube videos uploaded in 2025 with Ozempic in the title.
Methods: We performed a cross-sectional content analysis of 397 YouTube videos uploaded in 2025 with Ozempic in the title. Videos were categorized by duration as micro, short, standard, long, or extended. Outcomes included DISCERN-score, GQS-Score, JAMA benchmark criteria, TCCI score, usefulness score & engagement metrics. Theme coverage across eight educational domains was also compared.
Results: Among 397 videos, engagement increased with duration, with median views per day rising from 74.008 in micro-videos to 1018.681 in extended videos. Quality also improved with duration. Median DISCERN increased from 17.0 in micro videos to 30.0 in standard and extended videos, and median GQS increased from 1.0 in micro videos to 3.0 in standard, long, and extended videos. Title–content alignment improved, with TCCI ≥4 increasing from 24.7% in micro-videos to 70.0% in extended videos, and mean JAMA increased from 1.35-to-2.28. Educational themes were more common in longer videos, including the mechanism of action and safe use. Usefulness was modestly correlated with views/day.
Conclusions: In 2025, Ozempic-titled YouTube videos with a longer duration were associated with higher engagement, higher quality, and broader medication education. Transparency remained limited overall. Short videos may need clearer safety framing and stronger transparency cues.
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