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Intermittent hypoxic training as a novel strategy for obesity treatment: current evidence and future perspectives

diabetes-and-endocrinology
global-health
metabolic-sciences
obesity
sports-medicine

Abstract

Obesity is a metabolic disorder characterized by excessive accumulation of adipose tissue and is a recognized risk factor for numerous chronic diseases. Effective management of obesity has been proven to be essential to promote human health. Hypoxia, defined as insufficient oxygen supply to tissues and cells, is associated with pathological and pathophysiological conditions. In recent years, intermittent hypoxic training (IHT), a method involving exercise under controlled hypoxic conditions, has gained increasing popularity due to its demonstrated efficacy in improving various diseases. Notably, a growing body of research highlights the therapeutic potential of IHT in obesity, with increasing recommendations for its use as a feasible intervention. This review aims to critically discuss the effects of IHT on obesity and explore the underlying mechanisms responsible for its effectiveness, thereby providing evidence-based insights into how IHT exerts protective effects against obesity and advancing the understanding of its clinical applicability.
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