Effects of different seasonal use of antagonist ovulation induction protocols on in vitro fertilization embryo transfer: a retrospective cohort study


Abstract

Objective: To investigate the effect of antagonist ovulation induction program on embryo status and pregnancy outcome in infertile patients in different seasons.

Methods: A retrospective analysis of 1413 infertile patients who received IVF and antagonist ovulation induction program in the Reproductive Medicine Center of our hospital from January 2019 to December 2023 was conducted. According to different seasons, they were divided into spring group, summer group, autumn group, and winter group. The general information, embryo status, and pregnancy outcome of patients in each group were compared.

Results: There were no significant differences in female age, BMI, infertility type, total amount of Gn, e ndometrial thickness on day of transplantation, MII ovum rate, usable embryo rate, D3 embryo rate, blastocyst rate, HCG positive rate, clinical pregnancy rate, abortion rate and live birth rate among the four groups (P>0.05).

Conclusion: The results of embryo and pregnancy in infertile patients treated with antagonist ovulation induction protocol in different seasons can be better.

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