Biology & Life sciences - Table of Contents

September 30, 2025

DNA damage-dependent mechanisms of ionizing radiation-induced cellular senescence

Jiebing Guan, Tuo Li, Feifei Ma, Ning Wang, Huanteng Zhang, Jiale Li, Jianguo Li, Chang Xu, Qiang Liu

https://doi.org/10.7717/peerj.20087 PubMed 41048400

September 29, 2025

In vitro assessment of the impact of 30 CYP2C19 variants on citalopram metabolism

Peng Wang, Xiao-xia Hu, Jun-wei Li

https://doi.org/10.7717/peerj.20027 PubMed 41048387

September 26, 2025

Integrating network pharmacology, molecular docking, and molecular dynamics simulations to explore potential compounds and mechanisms of Coptis chinensis in treating streptococcal infections

Wanxiang Qi, Bin Shi, Wenqiang Tang, Jiangyong Zeng, Ma Zhuo, Hongcai Ma

https://doi.org/10.7717/peerj.19960 PubMed 41031039

September 26, 2025

Anticancer potential of ethanolic sidr leaf extracts against MCF-7 breast cancer cells: phytochemical, nutritional, and antimicrobial profile comparisons of different plant parts

Roqayah H. Kadi, Nashi K. Alqahtani, Ahmed M. Abdulfattah, Fayez Alsulaimani, Ahmed M. Basri, Reham M. Algheshairy, Hend F. Alharbi, Rokayya Sami, Amal Alyamani, Roua S. Baty, Ruqaiah I. Bedaiwi, Hala M. Abo-Dief, Nahid A. Osman, Nouf H. Alsubhi, Ashwaq M. Al-Nazawi, Manal Malibary

https://doi.org/10.7717/peerj.19858 PubMed 41031042

September 25, 2025

Effect of cirrhosis on prognosis in patients with acute-on-chronic liver failure: a systematic review and meta-analysis

Chunyang Dong, Xiaoxiao Liu, Dongshuai Zhang, Deyou Jiang

https://doi.org/10.7717/peerj.20049 PubMed 41025046

September 22, 2025

Predicting the prognosis of hepatocellular carcinoma based on genes related to polyamine metabolism

Chengli Liu, Meng Pu, Yingbo Ma, Shuhan Zhang, Qike Huang, Haoming Li, Tian Xia, Jingchen Zhang

https://doi.org/10.7717/peerj.19985 PubMed 41018906

September 17, 2025

Advances and challenges in research methods on oral absorption mechanisms of nano-formulations

Shu-jun Sun, Yi-Tong Liu, Jin-Yu Nie, Zheng-Yang Hu, Ze-Rong Liu, Hao Chen, Yong-zhi Hua, Shan Feng, Tao Yi, Ji-Fen Zhang

https://doi.org/10.7717/peerj.20032 PubMed 40980070

September 16, 2025

Comparison of the antibacterial properties of peptides from the hepatopancreas of red king crab and snow crab and development of an approach for red king crab peptide isolation from the hepatopancreas

Vladislav Molchanov, Alfiya Yunusova, Olesya Kazantseva, Alexander Yegorov, Alexander Lukin, Alexander Timchenko, Vitaly Novikov, Nikolay Novojilov, Maria Timchenko

https://doi.org/10.7717/peerj.19989 PubMed 40980063

September 16, 2025

Determination of metabolite differences between loquat nectar and honey by UPLC-MS/MS

Xin Sun, Rui Shu, Yuli Qu, Junjun Dai

https://doi.org/10.7717/peerj.19988 PubMed 40980058

September 11, 2025

Functional characteristics, intercellular interactions and pathophysiological associations of astrocytes in Parkinson’s disease

Ziying Li, Mengran Cao, Zhaoyang Yin, Xiaolei Li, Qinglu Wang, Panpan Dong, Caixia Zhou

https://doi.org/10.7717/peerj.19998 PubMed 40955304

September 3, 2025

Insight into the PmrB structures of colistin-resistant Gram-negative bacteria through the multi-template ligand-guided homology modeling and in silico mutagenesis

Nuttapat Anuwongcharoen, Chuleeporn Phanus-umporn, Chawalit Chatupheeraphat, Kamonlak Weakwiweak, Noramon Kaewsai, Warawan Eiamphungporn