Biology & Life sciences - Table of Contents

July 9, 2025

Clinical significance and heterogeneity of circulating tumor cells and clusters in breast cancer subtypes

LiangYu Hao, Lixiang Zheng

https://doi.org/10.7717/peerj.19703 PubMed 40656955

July 9, 2025

Effect of modulating the extracellular matrix cross linkage by genipin on tumor cell resistance and survival in thioacetamide-induced hepatocellular carcinoma in rats

Hanan M. Hassan, Mohammed Baradwan, Alaa Bagalagel, Reem Diri, Ahmed Basilim, Mohammed Z. Nasrullah, Abdulhamid Althagafi, Hussam I. Kutbi, Abdulaziz A. Mohammed, Hanan M. Alshan, Mohammed M.H. Al-Gayyar

https://doi.org/10.7717/peerj.19680 PubMed 40656954

July 9, 2025

Chronic sleep deprivation is associated with delayed puberty onset in rats, activation of proinflammatory cytokines and gut dysbiosis

Shirley Priscilla Gunawan, Shih-Yi Huang, Jhih-Wei Hsu, Chia-Yuan Lin, Nam Nhat Nguyen, Te-Hsuan Tung, Shu-Ling Liang, Gilbert Aaron Lee, Chien-Tien Su, Yang Ching Chen

https://doi.org/10.7717/peerj.19668 PubMed 40656962

July 8, 2025

Molecular evolution of TRPC4 regulatory sequences supports a role in mammalian thermoregulatory adaptation

Robert S. Cornman

https://doi.org/10.7717/peerj.19697 PubMed 40656937

July 8, 2025

In vivo assessment of pharmacokinetic interactions of empagliflozin and henagliflozin with sorafenib: an animal-based study

Wenyu Du, Zihan Liu, Zhi Wang, Xin Zhou, Zhanjun Dong, Ying Li

https://doi.org/10.7717/peerj.19662 PubMed 40656939

July 8, 2025

Research on the application of biomaterial-based responsive hydrogels in the tumor microenvironment

Wanrong Yue, Xiaoyu Zhu, Ming Wu, Wenyue Qiang, Yixin Yang, Ziyun Zhang, Youwei Wang, Yuanyin Teng, Mi Zhou

https://doi.org/10.7717/peerj.19609 PubMed 40873628

July 7, 2025

Utilizing loop-mediated isothermal amplification (LAMP) for detecting hemoglobin Constant Spring and hemoglobin Pakse mutations amidst the high prevalence and genetic heterogeneity of thalassemia in Thailand

Kasama Wongprachum, Nichakan Thitipoomdecha, Phakkamon Ananratanakit, Wattanakit Prakobkul, Unchasa Angkuranak, Nitchagan Sawangkul, Prapaporn Panichchob, Rossarin Karnpean, Wittaya Jomoui

https://doi.org/10.7717/peerj.19687 PubMed 40642331

July 7, 2025

Stock assessment and management implications of sailfin sandfish (Arctoscopus japonicus) caught by multiple fishing gears with different selectivity in Korean waters

Sung Il Lee, Eun-Gyu Kim, Jae-Hyeong Yang, Chang-Ik Zhang

https://doi.org/10.7717/peerj.19602 PubMed 40642326

July 7, 2025

Predicting and testing a gene network regulating seed germination in Arabidopsis

Ming Yang, Yixing Wang

https://doi.org/10.7717/peerj.19599 PubMed 40642330

July 7, 2025

Global stock structure of the Silky shark (Carcharhinus falciformis, Carcharhinidae) assessed with high-throughput DNA sequencing

Derek W. Kraft, Emily E. Conklin, Evan B. Freel, Melanie Hutchinson, Julia L.Y. Spaet, Robert J. Toonen, Zac H. Forsman, Michael I. Grant, John David Filmalter, John R. Hyde, Simon J.B. Gulak, Brian W. Bowen

https://doi.org/10.7717/peerj.19493 PubMed 40642325

July 4, 2025

Was Hupehsuchus a baleen whale-style filter feeder in the Early Triassic? A re-examination of the evidence

Ryosuke Motani, Nicholas D. Pyenson, Da-yong Jiang

https://doi.org/10.7717/peerj.19666 PubMed 40625919

July 4, 2025

Role of glycoproteins in hepatic lipid metabolism: emerging diagnostic markers and therapeutic targets

Bo Lan, Sixing Huang, Jinping Luo, Ping Shi, Zhe Qiang

https://doi.org/10.7717/peerj.19627 PubMed 40625923

July 4, 2025

Thymines opposite to bulky aristolactam-DNA adducts in duplex DNA are not targeted by human thymine-DNA glycosylase

Diana Manapkyzy, Gulzhan Zhamanbayeva, Viktoriya Sidorenko, Radha Bonala, Francis Johnson, Bakhyt T. Matkarimov, Dmitry Zharkov, Murat K. Saparbaev, Sabira Taipakova

https://doi.org/10.7717/peerj.19577 PubMed 40625924

July 3, 2025

Gibberellic acid-mediated transcriptional divergence underlies cold stress adaptation in two diploid cotton species

Dong Wang, Juyun Zheng, Ke Liu, Yanchao Xu, Dingsha Jin

https://doi.org/10.7717/peerj.19721 PubMed 40620777

July 3, 2025

Drought and rewatering effects on soybean photosynthesis, physiology and yield

Cheng Wang, Anni Sun, Li jie Zhu, Min Liu, Qi Zhang, Liwei Wang, Xining Gao

https://doi.org/10.7717/peerj.19658 PubMed 40620768

July 3, 2025

MDDeep-Ace: species-specific acetylation site prediction based on multi-domain adaptation

Yu Liu, Chaofan Ye, Can Lin, Kangkang Mao, Ming Zhu

https://doi.org/10.7717/peerj.19649 PubMed 40620770

July 3, 2025

Molecular and hematological characteristics of two different δ-globin promoter variants, δ^−276(A>G) and δ^{−77(T >C)} among Thai, Burmese, and Laotian subjects

Sitthichai Panyasai, Patcharawadee Prayalaw, Kritsada Singha, Supan Fucharoen

https://doi.org/10.7717/peerj.19636 PubMed 40620769

July 3, 2025

Serum miR-15a-5p may predict recurrence of atrial fibrillation after catheter ablation: a single center retrospective study

Zhong-Bao Ruan, Qian Peng, Xiang-Jiang Sun, Fei Wang, Li Zhu

https://doi.org/10.7717/peerj.19618 PubMed 40620773

July 3, 2025

EsoDetect: computational validation and algorithm development of a novel diagnostic and prognostic tool for dysplasia in Barrett’s esophagus

Migla Miskinyte, Benilde Pondeca, José B. Pereira-Leal, Joana Cardoso

https://doi.org/10.7717/peerj.19613 PubMed 40620772

July 2, 2025

High-frequency repetitive transcranial magnetic stimulation protects against 6-OHDA-induced Parkinson’s disease symptoms by modulating the proNGF-p75NTR-sortilin pathway

Rui Zhao, Wanqing Du, Ke Tian, Kunlong Zhang, Hua Yuan, Fang Gao, Xin Kang, Xiaolong Sun

https://doi.org/10.7717/peerj.19633 PubMed 40620776

July 1, 2025

Superoxide dismutase activity in tear fluid and blood of patients and mouse model of amyotrophic lateral sclerosis: a pilot study

Tatiana A. Pavlenko, Natalia B. Chesnokova, Olga V. Beznos, Natalia N. Shikareva, Marina R. Nodel, Ksenia V. Shevtsova, Uliana V. Panina, Daniil A. Shteinberg, Olga A. Kukharskaya, Iuliia S. Sukhanova, Nadezhda E. Pukaeva, Michail S. Kukharsky, Ruslan K. Ovchinnikov

https://doi.org/10.7717/peerj.19623 PubMed 40620778

July 1, 2025

Structural insights and biomedical potential of biosynthesized silver nanoparticles: antibacterial activity, anti-biofilm and cancer cell inhibition

Ikram Jemel, Najeh Krayem, Hajer Jlidi, Abir Ben Bacha, Mona Alonazi, Raihane Charguia, Areej Ali Alzahrani, Sami Aifa, Sami Mnif

https://doi.org/10.7717/peerj.19608 PubMed 40620779

July 1, 2025

Interictal neural fragility predicts seizure onset zone and surgical outcomes in drug-resistant epilepsy