Abhishek Tyagi

Summary

I have been working on the molecular mechanisms of cancer progression and metastasis for the last ten years, identifying signaling pathways that promote cancer progression using various in vitro and in vivo models. During this time, I have published 30 articles with more than 2000 citations, and 12 papers have been cited as being in the top 10% of the field. They have mostly appeared in high-impact journals such as Sci. Adv., Nat. Comm., J. Exp. Med., Clinical Can. Res., Oncogene, Cancer Res., Cancer Letters. My research is primarily concerned with mechanistic and translational studies of tumor-initiating cells, the microenvironment, and non-coding RNAs in the context of cancer progression and metastasis. My long-term research goal is to conduct basic and translational research to elucidate the underlying mechanism(s) driving cancer metastasis and identify therapeutic targets, especially for highly aggressive metastatic cancers. In addition, I also serve on the editorial boards of three cancer-related journals. Before joining the department of Cancer Biology at Wake Forest University School of Medicine, I was a senior research officer (SRO) at the Delhi State Cancer Institute, India (Govt. of India).
I am or have been...
1. A self-motivated, goal-oriented cellular/molecular biologist with over 7 years of experience in oncology.
2. Substantial experience in designing and executing well-controlled in vitro and in vivo assays for preclinical drug discovery, synthetic lethal screening, biomarker identification, target validation, immunogenicity, and toxicity assessment
3. Capable of investigating signaling pathways with a variety of molecular and genetic tools
4. Enthusiastic team worker and expert in forming strategic collaborations

Immunology Oncology Translational Medicine