Jeremy A. Bruenn

PeerJ Author

Summary

Professor, Department of Biological Sciences, SUNY/Buffalo (1987-present)
International Committee on the Taxonomy of Viruses (1986-present)
Senior Scientist, Hauptman-Woodward Medical Research Institute (1999-2002)

Ph.D. University of California, Berkeley
Postdoctoral Research at Oak Ridge National Laboratory and Cold Spring Harbor Laboratory

Bioinformatics Computational Biology Evolutionary Studies Genetics Genomics Molecular Biology Virology

Work details

Professor (Emeritus)

SUNY/Buffalo

Biological Sciences

This lab has worked on the molecular virology of small dsRNA viruses for over 25 years. Currently we are exploring the nature of the RNA-protein interaction that results in packaging of the viral plus strand. We have explored the RNA recognition site via PCR amplification techniques and defined the site as a small (20 base) region with a specific secondary structure. Similarly, the region of the large protein (over 1500 amino acids) that recognizes this sequence has been delimited to about 150 amino acids. We are now in the process of mutating each of these residues one at a time to map the contact residues.