Guang Yang

Guang Yang


Summary

WORK EXPERIENCE
08/2016 – present Stanford University, Palo Alto, U.S.
• Postdoctoral fellow in Huang lab
• Supervisor: Dr. Ngan F. Huang
• Research interest: endothelial potential of human induced pluripotent stem cells (iPSC) and engineered vascular graft

02/2016 – 07/2016 University of Pittsburgh, Pittsburgh, U.S.
• Postdoctoral associate in Center for Cellular and Molecular Biology
• Supervisor: Dr. Rocky S. Tuan
• Research interest: mesenchymal stem cell biology and tissue engineering

EDUCATION
PhD
09/2010 – 05/2016 University of Pittsburgh, Pittsburgh, U.S.
• Advisor: Dr. Rocky S. Tuan
• Dissertation research: Investigating the bio-activity of tendon-derived extracellular matrix on human adipose stem cells and the potential application in tendon tissue engineering

Bioengineering Biophysics Biotechnology Cell Biology Orthopedics

Institution affiliations

Work details

Postdoctoral fellow

Stanford University
Cardiothoracic Surgery
Endothelial cells (ECs) derived from human induced pluripotent stem cells (iPSCs) represents a promising patient-specific cell source for the treatment of peripheral arterial disease (PAD), which is prevalent in the United States. Adequate survival and angiogenesis of cell implant are the key to fully exploit the potential of iPSC-ECs in vascular repair and regeneration. My research is aiming at understanding regulatory effect of aligned nanofibrillar collagen scaffold that mimics the native nanostructure of the blood vessel ECM on iPSC-EC fate and function. We hypothesize that the topographical cues presented by the scaffold will cause cell alignment and improve cell survival, proliferation and angiogenic activities under hypoxia. We envision this tissue engineering approach to be clinically translatable to improve the blood perfusion and vasculature of PAD patients.

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PeerJ Contributions