Professor Zhou was graduated with BS in Chemical Physics from University of Science and Technology of China in 1984 and a PhD in Chemical Physics from State University of New York at Stony Brook in 1990. He switched his research field to computational biology when he was a postdoctoral research fellow at Harvard University with Professor Martin Karplus from 1995 t0 2000. He was an Assistant Professor and later Associate Professor at Department of Physiology and Biophysics at State University of New York at Buffalo from 2000 to 2006 and became a full Professor when he joined Indiana University School of Informatics at Indianapolis in 2006. He was a director of Bioinformatics program at the School of Informatics since 2007. Starting June 2013, He joined School of Information and Communication Technology and Institute for Glycomics at Griffith University as a Professor of Computational Biology. Dr. Zhou has published more than 170 peer reviewed articles and is known for his widely used bioinformatics tools such as SPARKS for protein structure prediction and DFIRE for protein binding and folding scoring functions.