I am a pediatric and adult hematologist specializing in sickle cell disease. My research projects range from clinical research to basic science. I will be opening a phase II clinical trial investigating treatments for Hemoglobin SC . My translational research project uses whole exome sequencing to study the pharmacogenomics of hydroxyurea. We also found that individuals with variants in FOXO3 had lower HbF, leading us to investigate the role of FOXO3 in erythropoiesis.