She is a Professor of Neuroscience, and Director of the Center on Alzheimer's Disease at Mount Sanai. Her laboratory studies the molecular genetics of dementias and addiction in human populations
She is Director of the Hope Center for Neurological Disorders and Associate Director of the Knight Alzheimer’s Disease Research Center.
She is the recipient of the Potamkin Prize for Alzheimer’s disease research, the Alzheimer’s Association Zenith Award, the Senior Investigator Award from the Metropolitan Life Foundation. She was elected Fellow AAAS.