Frederic Hopf

Summary

I study the mechanisms that promote motivated behavior, especially the compulsive drives that epitomize addiction. I combine sophisticated animal models to study substance abuse disorders with optogenetics, in vitro electrophysiology and shRNAs to identify drug-related changes that enhance pathological intake. I also seek to determine if depression and excessive anxiety, often co-morbid with alcoholism, are mediated by these signaling pathways and by dopamine and neuro-peptides.

Cell Biology Neuroscience

Work details

Assistant Adjunct Professor

Gallo Research Center, Univ. of Calif. San Francisco

Neurology

Articles published in PeerJ

MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro

April 9th, 2013

F Woodward Hopf, Taban Seif, Shinjae Chung, Olivier Civelli