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Charles H Williams
Summary
Dr. Charles (Chuck) Williams is an Assistant Professor at Michigan State University, and is a basic scientist whose research centers on chemical genetics of vertebrate development and early drug discovery. His research functions at the intersection of developmental biology, chemical biology, computational biology, and personalized medicine. Dr. Williams' work includes innovative chemical biologic approaches to study embryonic development as well as developing resources to facilitate academic drug discovery.
His research has made contributions to the emerging field of chemical genetics through the discovery of chemical modulators of several key developmental pathways, including the Eggmanone, a small molecule inhibitor of the Hedgehog pathway. This work revealed novel biological insights and new therapeutic opportunities for targeting cancers downstream of the Smoothened receptor which handles the clinical problem of acquired smoothened resistance in medulloblastoma. In addition, Dr. Williams edited a book covering the latest methods and protocols in chemical biology. He has recently co-founded a start-up around a new technology for targeting glioblastoma.
Dr. Williams received a PhD in cell and developmental biology from Vanderbilt University, where he also received his BS in Molecular and Cellular Biology.
Biotechnology Cell Biology Developmental Biology Drugs & Devices
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