Bioinformatics and Genomics

Ensemble learning for detecting gene-gene interactions in colorectal cancer
Jin-Kao Hao –– The work tackles an important topic with an interesting approach and advances the state of the art in the field.
Distributed Bayesian networks reconstruction on the whole genome scale
Jürg Bähler –– A new method for reconstructing large transcriptional networks that removes some of the computational bottlenecks of such genome-scale analyses.
BdBG: a bucket-based method for compressing genome sequencing data with dynamic de Bruijn graphs
Elena Papaleo –– A new and interesting approach to improve compression of sequencing data to tackle the related issues in NGS data processing.
Does Twitter language reliably predict heart disease? A commentary on Eichstaedt et al. (2015a)
Tjeerd Boonstra –– The article re-examines the results of an influential paper and challenges the idea that social media data analysed on a county-level may provide a reliable predictor of health outcomes. The authors raise several questions on the reliability of data and study design that need to be addressed for this field going forward.
Application of EST-SSR markers developed from the transcriptome of Torreya grandis (Taxaceae), a threatened nut-yielding conifer tree
Pankaj Jaiswal –– This article on Torreya grandis (Taxaceae) an ancient conifer species that is endemic to southeast China provides an important insight into the population structure and distribution of the species. It also generated the genomic resources necessary to move forward the research on Torreya grandis.
Metabolic marker gene mining provides insight in global mcrA diversity and, coupled with targeted genome reconstruction, sheds further light on metabolic potential of the Methanomassiliicoccales
Peter Dunfield –– Will specificaly interest those working on methanogenesis, but more broadly the technical novelty may appeal to many microbial ecologists interested in mining metagenomic datases.
Exome sequencing study of 20 patients with high myopia
Yong Wang –– This paper performed exom sequencing to study high myopia and identified several potential disease genes. The data and analysis provides a valuable resources for the field.
Plant data visualisation using network graphs
Massimiliano Zanin –– An interesting demonstration on how data can be represented using new web-based technologies.
Energy cost associated with moving platforms
Michael Holmes –– Can provide valuable information for health and safety experts.
A minimal set of internal control genes for gene expression studies in head and neck squamous cell carcinoma
Elena Papaleo –– An interesting solution to identify a subset of reference genes for qualitative qPCR of cancer samples
Bioinformatics and Genomics

Section discussions

Platygyra verweyi in the Kenting Reef undergoes long-term acclimatization and/or adaptation based on microgeographic and local environmental conditions by altering its combinations of associated Symbiodiniaceae.

Predicting the consequences of global warming on Gentiana lutea germination at the edge of its distributional and ecological range @thePeerJ

Identification of key genes associated with progression and prognosis for lung squamous cell carcinoma @thePeerJ

Transcriptomic profiling of purple broccoli reveals light-induced anthocyanin biosynthetic signaling and structural genes @thePeerJ

My article - Zooplankton in two cascade reservoirs - has been published today in @thePeerJ #Biodiversity #Ecology #EcosystemScience #FreshwaterBiology #Ecohydrology