Biochemistry, Biophysics and Molecular Biology

In vitro anticancer activity of methanolic extract of Granulocystopsis sp., a microalgae from an oligotrophic oasis in the Chihuahuan desert
Vladimir Uversky –– This work describes anticancer activity of the extract of microalgae from the Cuatro Cienegas Basin (CCB), an oasis in the Chihuahuan desert in Mexico and suggests that it represents a promising alternative against cancer.
Transcriptome profiling of kenaf (Hibiscus cannabinus L.) under plumbic stress conditions implies the involvement of NAC transcription factors regulating reactive oxygen species-dependent programmed cell death
Kun Lu –– An interesting heavy metal adaption mechanism in plants.
Suppression of osteogenic differentiation and mitochondrial function change in human periodontal ligament stem cells by melatonin at physiological levels
Dunxian Tan –– This study has obvious clinical implication related to the potential association of melatonin levels and bone formation. This association has not been clarified previously.
Endoplasmic reticulum stress and the protein degradation system in ophthalmic diseases
Gwyn Gould –– ER stress and the UPR play important roles in the pathology of many diseases, including ophthalmic conditions. This review addresses the role of the ER, autophagy and ubiquitin in these diseases with an examination of the role of ER stress and UPR as a particular focus.
Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences
Ruslan Kalendar –– The nucleotide composition and its complexity is not random and has different evolutionary and functional features. The study of such sites is important and demonstrates the multiple effects of GC-rich sequences enriched in guanine quadruplexes interaction with proteins.
Homeoprotein OTX1 and OTX2 involvement in rat myenteric neuron adaptation after DNBS-induced colitis
Jerson Silva –– The study evidences that colitis up-regulates OTX1 and OTX2 in myenteric plexus, with a potential participation in the inflammatory-related myenteric ganglia remodeling processes.
Development and validation of statistical shape models of the primary functional bone segments of the foot
Tim Doyle –– Statistical shape models are increasing in their use. As such, research like this is needed.
A simple and efficient cloning system for CRISPR/Cas9-mediated genome editing in rice
Kun Lu –– CRISPR-Cas9 based genome editing has become the method of choice for the rapid generation of transgenic plants. We hope that the fast and efficient cloning system the authors presented could facilitate genetic engineering in plants.
Flavonoids from Epimedium pubescens: extraction and mechanism, antioxidant capacity and effects on CAT and GSH-Px of Drosophila melanogaster
Chin Ping Tan –– This paper highlights work related to ultrasound extraction of flavonoids from Epimedium pubescens and subsequent evaluation on antioxidant properties and effect of the extract on fruit flies.
DNA methylation profiling in recurrent miscarriage
Vladimir Uversky –– This study can be useful for better understanding of the molecular basis of recurrent miscarriage
Biochemistry, Biophysics and Molecular Biology

Section discussions

First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells @thePeerJ

New article @PeerJLife #Biodiversity #Biogeography #MarineBiology #MolecularBiology

New insight into the divergent responses of plants to warming in the context of root endophytic bacterial and fungal communities Read the full @PeerJLife article #Ecology #Microbiology #Mycology #PlantScience

The #GRAS gene family in #watermelons: identification, characterization and expression analysis of different tissues and root-knot nematode infestations Read the full @PeerJLife article #Agriculture #Genomics #PlantScience #SoilScience

Identification and analysis of Chrysanthemum nankingense NAC transcription factors and an expression analysis of OsNAC7 subfamily members @thePeerJ

#Paracercion are common ‘blue and black’ colored #damselflies. @PeerJLife article explores the species boundaries of Paracercion using distance-based clustering Read the full article #Entomology #MolecularBiology #Taxonomy

Evaluation of pro-apoptotic potential of taxifolin against liver cancer @thePeerJ