Biochemistry, Biophysics and Molecular Biology

Porphyromonas gingivalis lipopolysaccharide promotes T-hel per17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes
Joseph Gillespie –– Zhang et al. describe the role of monocytes and T-cell in the progression of periodontal disease, one of the most important oral disease.
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells
Eva Mezey –– Understanding the many mechanisms of osteoporosis will eventually lead for novel therapeutic approaches. This paper suggests the role of a long non-coding RNA in the pathophysiology.
Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells
Maria Cristina Albertini –– Important results have been found with advances in colorectal cancerogenesis.
Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant
Abhiram Maddi –– Production of vaccines in plants may be an important approach in the future as we deal with the current pandemic.
The effect of carbon monoxide on meiotic maturation of porcine oocytes
Judith Yanowitz –– The impact of carbon monoxide on oocyte maturation has the potential to change in vitro culturing methodology to increase oocyte quality.
Preparation and characterization of gelatin-polysaccharide composite hydrogels for tissue engineering
Omar Gonzalez-Ortega –– The potential final application is attractive. Despite this, there is still work to be done to "optimize" the composite gel.
Exploring the occurrence of thioflavin-T-positive insulin amyloid aggregation intermediates
Eugene Permyakov –– Any new information on insulin properties is of importance for medicine.
Effective ribosomal RNA depletion for single-cell total RNA-seq by scDASH
Joseph Gillespie –– Loi et al. describe a novel approach for performing rRNA depletion in single cell sequencing experiments that facilitates detection of non-polyadenylated and partially degraded RNAs.
Research on the measurement of intracranial hemorrhage in rabbits by a parallel-plate capacitor
Jafri Abdullah –– More portable star trek like scanning equipment are important for screening blood clots in the brains are needed
Identification and molecular characterization of mutations in nucleocapsid phosphoprotein of SARS-CoV-2
Timothy Newsome –– Understanding the significance of SARS-CoV-2 genomic changes is key to an effective response in the current pandemic. This new research identified the N-protein as a mutational hotspot, with potential implications to a number of aspects of virus replication.
Biochemistry, Biophysics and Molecular Biology

Section discussions

The protective effect of Moringa oleifera plant extract against glutamate-induced DNA damage and reduced cell viability in a primary retinal ganglion cell line @thePeerJ

Ji et al. present a prospective cohort study - Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction Read the full @PeerJLife article #MolecularBiology #Cardiology #Medicine

Elucidating SNP-based genetic diversity and population structure of advanced breeding lines of bread wheat (Triticum aestivum L.) @thePeerJ

Potency of #bisresorcinol from Heliciopsis terminalis on skin aging: in vitro bioactivities and molecular interactions - Research from Saechan et al. published in @PeerJLife #DataMining #MachineLearning #Biochemistry

Retinal dysfunction induced in a mouse model of unilateral common carotid artery occlusion @thePeerJ