Biochemistry, Biophysics and Molecular Biology

Editors' Picks

Histopathological analysis of zebrafish after introduction of non-biodegradable polyelectrolyte microcapsules into the circulatory system
Vladimir Uversky –– This study is of great interest and importance for specialists in aquatic science
Porphyromonas gingivalis lipopolysaccharide promotes T-hel per17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes
Joseph Gillespie –– Zhang et al. describe the role of monocytes and T-cell in the progression of periodontal disease, one of the most important oral disease.
Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells
Eva Mezey –– Understanding the many mechanisms of osteoporosis will eventually lead for novel therapeutic approaches. This paper suggests the role of a long non-coding RNA in the pathophysiology.
Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated KRAS colorectal cancer cells
Maria Cristina Albertini –– Important results have been found with advances in colorectal cancerogenesis.
Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant
Abhiram Maddi –– Production of vaccines in plants may be an important approach in the future as we deal with the current pandemic.
The effect of carbon monoxide on meiotic maturation of porcine oocytes
Judith Yanowitz –– The impact of carbon monoxide on oocyte maturation has the potential to change in vitro culturing methodology to increase oocyte quality.
Preparation and characterization of gelatin-polysaccharide composite hydrogels for tissue engineering
Omar Gonzalez-Ortega –– The potential final application is attractive. Despite this, there is still work to be done to "optimize" the composite gel.
Segmental analysis by speckle-tracking echocardiography of the left ventricle response to isoproterenol in male and female mice
Gwyn Gould –– Highlights the use of Speckle Tracking Echocardiography with an interesting mouse model.
Expression analysis of genes related to cold tolerance in Dendroctonus valens
Jasmine Janes –– The article adds to a growing body of knowledge around cold tolerance, insects and in particular, forest pest expansion with respect to cold tolerance.
Luzindole and 4P-PDOT block the effect of melatonin on bovine granulosa cell apoptosis and cell cycle depending on its concentration
Dunxian Tan –– This article describes the importance of melatonin on animal reproduction, particularly related to the granulosa cell apoptosis and cell cycle. These actions are probably mediated by the melatonin concentrations and membrane receptors locally. It provides useful information related to the reproductive physiology in large animals.
Biochemistry, Biophysics and Molecular Biology

Section discussions

Just published @PeerJLife study examines the long-term effects of non-biodegradable polyelectrolyte microcapsules on fish internal organs with histopathologic analysis Read the full article #Aquaculture #Fisheries #Biochemistry #Biotechnology

Research from Langenfeld et al. @UMich compares ultrafiltration and iron chloride flocculation in the preparation of aquatic viromes from contrasting sample types Read the full @PeerJLife article @envirophage #Microbiology #MolecularBiology #Virology

3 days ago
Analysis of Odonata #DNAbarcode library today in @thePeerJ #Entomology #MolecularBiology #Taxonomy #Zoology #FreshwaterBiology