Biochemistry, Biophysics and Molecular Biology

The impact of PI3K inhibitors on breast cancer cell and its tumor microenvironment

Editor rating: 6 / 10

Heiko Enderling –– understanding the mechanisms and action of PI3K inhibitors alone and in in combination will lay the foundation for successful prospective clinical trials of new cancer treatment strategies.
Crucial biological functions of CCL7 in cancer

Editor rating: 7 / 10

Howard Young –– This is a valuable review on an important topic that is not often reviewed. Thus it will provide a better understanding of the state of the literature on this important chemokine pathway.
How well do force fields capture the strength of salt bridges in proteins?

Editor rating: 8 / 10

Emanuele Paci –– The paper provides a test case for testing polarizable force fields for the simulations of proteins.
Pretreating mesenchymal stem cells with electrical stimulation causes sustained long-lasting pro-osteogenic effects

Editor rating: 7 / 10

Eva Mezey –– MSCs have a central role in regenerative medicine as well as in immune-regulation. Thus any manipulation that affects the function of these cells is significant since it might alter their character and affect their use.
MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus

Section Editor rating: 6 / 10

Vladimir Uversky –– Interesting paper about important protein
Comparing the biomechanical characteristics between squat and standing serves in female table tennis athletes

Editor rating: 7 / 10

Silvia Comani –– The information provided on the table tennis serve technique can be relevent to athletes and coaches.
Proteomics of Nasonia vitripennis and the effects of native Wolbachia infection on N. vitripennis

Editor rating: 6 / 10

Joseph Gillespie –– It provides important information on host response to a parasitic microbe
A guideline for reporting experimental protocols in life sciences

Editor rating: 6 / 10

Todd Vision –– An important effort to help define actionable community standards for experimental protocols.
An improved primer set and amplification protocol with increased specificity and sensitivity targeting the Symbiodinium ITS2 region

Editor rating: 8 / 10

Tomas Hrbek –– Optimized protocol for amplification of Symbiodinium ITS2 region, that makes great strides towards generating reproducible and comparable data across a diversity of studies.
Breast fibroblasts in both cancer and normal tissues induce phenotypic transformation of breast cancer stem cells: a preliminary study

Editor rating: 7 / 10

Leticia Costa-Lotufo –– The research field is quite important and up to date in cancer biology studies.

Discussing these articles

Pretreating mesenchymal stem cells with electrical stimulation causes sustained long-lasting pro-osteogenic effects https://t.co/QcuMNQiYYy @thePeerJ https://t.co/AKFOPol5Dq

MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus https://t.co/HJjQzg6Xyd @thePeerJ https://t.co/NQaqYTc2Gs

Comparing the biomechanical characteristics between squat and standing serves in female table tennis athletes https://t.co/m1Ke4ir1zZ @thePeerJ https://t.co/P5MjvRMdbF

How to report experimental protocols? Guideline for reporting protocols https://t.co/c0CbJTuoBj

Proteomics of Nasonia vitripennis and the effects of native Wolbachia infection on N. vitripennis https://t.co/CHWQFp148B @thePeerJ https://t.co/gUHIKCHwtC

to all peeps doing #Symbiodinium ITS2 typing: check out the new & improved primer pair and robust PCR protocol .. works well in particular for non-host environments https://t.co/zz8DZyLON3 .. ground truthing & future proofing ITS2 @TaraExpeditions @thePeerJ @KAUST_News