Editor rating: 7 / 10Jie Liu –– HMGB1 is an important target.
Editor rating: 7 / 10Sandhya Visweswariah –– A good review possibly the only one dealing in this area.
Editor rating: 9 / 10Ilaria Negri –– Aedes albopictus is an invasive mosquito species, able to adapt to many environments. This article helps to shed light on its ecology.
Editor rating: 8 / 10Robert Druzinsky –– This is a new approach to a long-standing problem in the biomechanics of rodent feeding.
Editor rating: 7 / 10Carlo Ennio Pucillo –– it is of interest to the people that work on the specific topic,
Editor rating: 8 / 10Regina-Michaela Wittich –– The input of commercial materials.
Editor rating: 7 / 10Yegor Vassetzky –– The MS describes the transfer of viral helicases to insect retrotransposons.
Editor rating: 8 / 10Curtis Daehler –– While numerous studies have pointed out threats posed by hybridization between native and invasive species, this work provides a counter-example: Although hybrids were detected, hybridization does not seem to pose a risk to the native species or promote spread of the invader.
Editor rating: 8 / 10Erich Schwarz –– To my knowledge, this is the first reporter for miRNA activity that works without secondary gene products (proteins) that can, at best, work in a cumbersome and unreliable manner to generate readouts from miRNA action. This reporter has the potential to applied therepeutically to induce cell-specific gene activity (either of a toxin gene, or of some other desired gene) in only those cells that happen to be expressing a particular miRNA (such as onco-miRNAs). This reporter should be able to work in any cell type of any metazoan with functioning miRNAs. The reasoning that led to this work is clear, direct, and elegant. The minor technical imperfections, which the authors scrupulously report in their statistical analysis, may well be overcome by future optimization of the RNA hairpins used by the reporter (perhaps by in vitro evolution of the miRNA reporter itself).
Editor rating: 7 / 10Can Küçük –– DAPK1 expression level can be used as a prognostic biomarker in liver cancer which can potentially be used to choose better therapeutical option(s) based on its level.
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