Editor rating: 7 / 10Yegor Vassetzky –– The MS describes the transfer of viral helicases to insect retrotransposons.
Editor rating: 8 / 10Curtis Daehler –– While numerous studies have pointed out threats posed by hybridization between native and invasive species, this work provides a counter-example: Although hybrids were detected, hybridization does not seem to pose a risk to the native species or promote spread of the invader.
Editor rating: 8 / 10Erich Schwarz –– To my knowledge, this is the first reporter for miRNA activity that works without secondary gene products (proteins) that can, at best, work in a cumbersome and unreliable manner to generate readouts from miRNA action. This reporter has the potential to applied therepeutically to induce cell-specific gene activity (either of a toxin gene, or of some other desired gene) in only those cells that happen to be expressing a particular miRNA (such as onco-miRNAs). This reporter should be able to work in any cell type of any metazoan with functioning miRNAs. The reasoning that led to this work is clear, direct, and elegant. The minor technical imperfections, which the authors scrupulously report in their statistical analysis, may well be overcome by future optimization of the RNA hairpins used by the reporter (perhaps by in vitro evolution of the miRNA reporter itself).
Editor rating: 7 / 10Can Küçük –– DAPK1 expression level can be used as a prognostic biomarker in liver cancer which can potentially be used to choose better therapeutical option(s) based on its level.
Editor rating: 7 / 10Rüdiger Ettrich –– I am convinced that the article indeed contributes to a deeper global understanding of the Aliivibrio salmonicida Fur regulon and reaches out to the adjacent disciplines. Thus the statement in the title is not overstated but indeed advertises the findings in this paper.
Editor rating: 7 / 10Maria Concetta Geloso –– The study adds useful information about the role of FGFR1 signaling during brain development.
Editor rating: 8 / 10Padmapriya Banada –– this article addresses important issues in cell biology regarding the influence of high confluence on the expression of enriched miRNAs in beta cells. this is supported by additional studies which has also showed that confluency of cells can influence gene expression.
Editor rating: 7 / 10Vincenzo Brancaleone –– The article is important beacuse of the role of phytochemical extracts in treatment of bacterial infection
Editor rating: 7 / 10Mauricio Rodriguez-Lanetty –– This study provides insights into the underlying thermodynamic mechanisms involved in the microbial food web associated with coral and macroalgae interactions.
Editor rating: 7 / 10Nigel Andrew –– bee responses to chemical exposure - high profile issues at the moment
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