Biochemistry, Biophysics and Molecular Biology

Characterizing metabolic stress-induced phenotypes of Synechocystis PCC6803 with Raman spectroscopy
Siouxsie Wiles –– New tools to study bacterial response to stresses/environmental changes.
Icariin affects cell cycle progression and proliferation of human retinal pigment epithelial cells via enhancing expression of H19
Diego Wilke –– Natural products are a prolific source if medicines highly relevant to treat countless human diseases. In this paper, icaridin effects suitable to treat retinopathy is depicted.
In vitro anticancer activity of methanolic extract of Granulocystopsis sp., a microalgae from an oligotrophic oasis in the Chihuahuan desert
Vladimir Uversky –– This work describes anticancer activity of the extract of microalgae from the Cuatro Cienegas Basin (CCB), an oasis in the Chihuahuan desert in Mexico and suggests that it represents a promising alternative against cancer.
Transcriptome profiling of kenaf (Hibiscus cannabinus L.) under plumbic stress conditions implies the involvement of NAC transcription factors regulating reactive oxygen species-dependent programmed cell death
Kun Lu –– An interesting heavy metal adaption mechanism in plants.
Suppression of osteogenic differentiation and mitochondrial function change in human periodontal ligament stem cells by melatonin at physiological levels
Dunxian Tan –– This study has obvious clinical implication related to the potential association of melatonin levels and bone formation. This association has not been clarified previously.
Endoplasmic reticulum stress and the protein degradation system in ophthalmic diseases
Gwyn Gould –– ER stress and the UPR play important roles in the pathology of many diseases, including ophthalmic conditions. This review addresses the role of the ER, autophagy and ubiquitin in these diseases with an examination of the role of ER stress and UPR as a particular focus.
Tight DNA-protein complexes isolated from barley seedlings are rich in potential guanine quadruplex sequences
Ruslan Kalendar –– The nucleotide composition and its complexity is not random and has different evolutionary and functional features. The study of such sites is important and demonstrates the multiple effects of GC-rich sequences enriched in guanine quadruplexes interaction with proteins.
Homeoprotein OTX1 and OTX2 involvement in rat myenteric neuron adaptation after DNBS-induced colitis
Jerson Silva –– The study evidences that colitis up-regulates OTX1 and OTX2 in myenteric plexus, with a potential participation in the inflammatory-related myenteric ganglia remodeling processes.
Development and validation of statistical shape models of the primary functional bone segments of the foot
Tim Doyle –– Statistical shape models are increasing in their use. As such, research like this is needed.
A simple and efficient cloning system for CRISPR/Cas9-mediated genome editing in rice
Kun Lu –– CRISPR-Cas9 based genome editing has become the method of choice for the rapid generation of transgenic plants. We hope that the fast and efficient cloning system the authors presented could facilitate genetic engineering in plants.
Biochemistry, Biophysics and Molecular Biology

Section discussions

100 visitors to my 'Fast computational mutation-response scanning of proteins' article published in #OpenAccess journal @thePeerJ

An interesting article I handled as editor has been published today @thePeerJ @PeerJLife #Aquaculture,FisheriesandFishScience #Biotechnology #MarineBiology #Microbiology

New research from @UArkansas @USDA - Soil microbial diversity in organic and non-organic pasture systems Read the full @PeerJLife article #AgriculturalScience #Bioinformatics #Microbiology

Photoperiod induced the pituitary differential regulation of lncRNAs and mRNAs related to reproduction in sheep @thePeerJ

Transfection types, methods and strategies: a technical review @thePeerJ

Wang et al. examine genome-wide identification and expression analysis of the EXO70 gene family in #grape Read the full @PeerJLife article #AgriculturalScience #Genomics #MolecularBiology #PlantScience

Long non-coding RNA taurine upregulated gene 1 is downregulated in osteoporosis and influences the osteogenic differentiation of bone marrow mesenchymal stem cells @thePeerJ

Research from @CUBoulder examines the widely assumed phenotypic associations in #Cannabis #sativa discovering a lack of shared genetic basis Read the full @PeerJLife article #Cannabinoid #Chemotype #Hemp #Marijuana