Biochemistry, Biophysics and Molecular Biology

Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells
Jörg Oehlmann –– The article provides evidence on topic which has been discussed intesively in science and the media: a potential interaction of brodifacoum with human cannabinoid receptors. While it has been speculated that brodifacoum may enhance the effects of cannabinoids, this article clearly shows that bordifacoum does not interact with human CB1 and CB2 receptors as the most probable target structure.
Development of a highly sensitive magneto-enzyme lateral flow immunoassay for dengue NS1 detection
Mario Alberto Flores-Valdez –– Point of care methods or devices are highly desirable to speed up diagnosis of several diseases including dengue
Effect of biomimetic material on stress distribution in mandibular molars restored with inlays: a three-dimensional finite element analysis
Abhiram Maddi –– Biomimetic materials are materials that represent cutting edge technology.
Design, synthesis and antimicrobial activities of novel 1,3,5-thiadiazine-2-thione derivatives containing a 1,3,4-thiadiazole group
Eder Lenardao –– The invention of new compounds to fight against phytopathogenic microorganisms is significant, once these deseases affects the crop production, leading to large annual economic losses.
Metabolomic analysis reveals the mechanism of aluminum cytotoxicity in HT-29 cells
Ramamoorthy Siva –– There are limited research on Aluminium toxicity on intestinal cell line and this article highlights the possible genes involved
Delivery of targeted gene therapies using a hybrid cryogel-coated prosthetic vascular graft
Omar Gonzalez-Ortega –– This works describe initial studies on a composite hydrogel that could be used for a health application.
The clinical value of carcinoembryonic antigen for tumor metastasis assessment in lung cancer
Abhiram Maddi –– This manuscript is about a novel diagnostics marker for metastasis of lung cancer and may forward the field of diagnostics.
Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats
Dunxian Tan –– Aging associated changes of the CP450 is important for aging research in the field
The extent to which genetics and lean grade affect fatty acid profiles and volatile compounds in organic pork
Mohammed Gagaoua –– Nowdays, organic foods are very important. This one of the most interesting studies in the field of animal (pig) products.
Upregulation of SPOCK2 inhibits the invasion and migration of prostate cancer cells by regulating the MT1-MMP/MMP2 pathway
Cheng-Chia Yu –– SPOCK2 is associated with the progression of prostate cancer and upregulation of SPOCK2 can inhibit invasion and metastasis.
Biochemistry, Biophysics and Molecular Biology

Section discussions

4 days ago
New publication from Haigh lab and his collaborators identify SARS-CoV-2 founder mutations in samples from China, USA, Australia and GenBank sequences with the greatest number of mutations in the US samples. #covid19 via @thePeerJ

250 visitors to my 'VIRdb: a comprehensive database for interactive analysis of genes/proteins involved in the pathogenesis of vitiligo' article published in #OpenAccess journal @thePeerJ

Bioinformatics analyses of retinoblastoma reveal the retinoblastoma progression subtypes @thePeerJ

Another interesting article I handled as editor has been published today @thePeerJ #Biotechnology #MolecularBiology #Toxicology #Pharmacology #Histology

High expression of stromal signatures correlated with macrophage infiltration, angiogenesis and poor prognosis in glioma microenvironment @thePeerJ

Distribution of the acoustic occurrence of dolphins during the summers 2011 to 2015 in the Upper Gulf of California, Mexico @thePeerJ