Biochemistry, Biophysics and Molecular Biology

Article commentary

The little shrimp that could: phylogeography of the circumtropical Stenopus hispidus (Crustacea: Decapoda), reveals divergent Atlantic and Pacific lineages

Editor rating: 8 / 10

Xavier Pochon –– This study provides the first range-wide phylogeographic study of the banded coral shrimp S. hispidus, extending across more than 27,000 km of the globe. Coalescence analysis brings evidence that an isolated Indo-Pacific lineage evolved from a rare dispersal event from the Atlantic around South Africa via the Benguela Current, thereby colonizing the Indian and Pacific Oceans, followed by dispersal across the Indo-Pacific in the last 200,000 years. Surprisingly, this benthic coral reef associated shrimp shows a single haplotype dominating the largest continuous tropical oceanic expanse on the planet.
Identification and characterization of the cytosine-5 DNA methyltransferase gene family in Salvia miltiorrhiza

Editor rating: 7 / 10

Gerrit Beemster –– Epigenetic regulation is rapidly becoming a new regulatory mechanism in developmental processes and this study is a nice contribution to that field using a non model species.
Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test

Editor rating: 8 / 10

Fernando Spilki –– The manuscript describes a new technique for quick detection of anti-HIV1/2 IgM.
Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding

Editor rating: 8 / 10

Jerson Silva –– This work has the novelty to provide a detailed investigation of structure – thermodynamics relationship of the protein recognition process.
Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs

Editor rating: 7 / 10

Marc Robinson-Rechavi –– This study allows to link natural variation in morphology with genetic divergence in expression patterns, thus helping link ecology to molecular genomics.
Complex versus simple models: ion-channel cardiac toxicity prediction

Editor rating: 8 / 10

Heiko Enderling –– This article discusses the contributions of quantitative models in predicting biology, and makes an important point about the balance of simplicity/complexity/accuracy/usefulness of biophysical models. If simple models capture biological complexity, the use of more detailed models must be properly justified.
Development of an RNA interference (RNAi) gene knockdown protocol in the anaerobic gut fungus Pecoramyces ruminantium strain C1A

Editor rating: 8 / 10

Alexandra Lusser –– The article describes the development of a new method in this field that should facilitate future research in this area.
Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review

Editor rating: 7 / 10

Jun Pang –– It is a very interesting literature review.
Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome

Editor rating: 7 / 10

Shih-Pin Chen –– This study provides more evidences supporting the possible association of gut eukaryotic composition with inflammation in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Lipid raft localization of TLR2 and its co-receptors is independent of membrane lipid composition

Editor rating: 8 / 10

Ayyalusamy Ramamoorthy –– The findings on the membrane domain localization is important and useful.

Discussing these articles

Our research has been peer reviewed and now appears in print. We are pleased to confirm that OraQuick Advance HIV ½ Antibody Test has been proven to detect IgM Antibodies thus allowing our customers to reliably detect HIV earlier i…https://t.co/IlqZOUgiPq https://t.co/cAAUzCceR2

The little shrimp that could: phylogeography of the circumtropical Stenopus hispidus (Crustacea: Decapoda), reveals divergent Atlantic and Pacific lineages https://t.co/TXOB7dyxro https://t.co/QkZN9Zfxz0

Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs Good job @vonStadarhraun https://t.co/SKVXoWQ3Ix via @thePeerJ

new publication: https://t.co/MONo6omrX3 a comprehensive analysis on how a well-defined simple heuristic is as good (if not better) than complex mathematical models, used by FDA and bloated pharma companies, in ion-channel safety pharmacology #mathbiology

Our article has been published today in @thePeerJ https://t.co/xsVSirvY3c. Well done Abby Peters - another PhD output! @livuniAgeing @livunieng #Bioengineering #Biotechnology #ComputationalBiology

"Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome": https://t.co/5UKkoepUbU