Biochemistry, Biophysics and Molecular Biology

An investigation into the bilateral functional differences of the lower limb muscles in standing and walking

Editor rating: 8 / 10

Yong Wang –– The authors investigated whether the left limb and the one of the right limb have the same statistical characteristics during functional tasks.
The core clock gene Per1 phases molecular and electrical circadian rhythms in SCN neurons

Editor rating: 7 / 10

Michael Henson –– This article further clarifies the relationship between neural firing and core clock activity in the SCN.
The antioxidative properties of S-allyl cysteine not only influence somatic cells but also improve early embryo cleavage in pigs

Editor rating: 7 / 10

Xiang-Jiao Yang –– This is important for embryo manipulation in vitro.
Will 1,2-dihydro-1,2-azaborine-based drugs resist metabolism by cytochrome P450 compound I?

Editor rating: 8 / 10

Paul Tulkens –– This is an interesting approach to decipher, prospectively, the potential for metabolism (or lack thereof) of novel drug compounds.
Phage on tap–a quick and efficient protocol for the preparation of bacteriophage laboratory stocks

Editor rating: 8 / 10

Siouxsie Wiles –– It describes a new method which should be widely used in the field
Computational fluid dynamics modelling of left valvular heart diseases during atrial fibrillation

Editor rating: 7 / 10

Ebba Brakenhielm –– This work provides a novel integrated model for how valvular stenosis (aortic vs mitral) influence hemodynamics in the setting of atrial fibrillation.
Detection of methylation, acetylation and glycosylation of protein residues by monitoring 13C chemical-shift changes: A quantum-chemical study

Editor rating: 7 / 10

Rüdiger Ettrich –– I think the article might nicely advertise how computational predictions can complement experimental data in a useful way. This makes the article interesting not only for the NMR community but to protein chemists in general.
The modulatory effect of Moringa oleifera leaf extract on endogenous antioxidant systems and inflammatory markers in an acetaminophen-induced nephrotoxic mice model

Editor rating: 7 / 10

Cristina Nogueira –– This is a very intersting manuscript because highlights nephrotoxicity induced by acetominophen, a well known pain reliever.
Virus wars: using one virus to block the spread of another

Editor rating: 7 / 10

Tomas Perez-Acle –– This interesting work proposes a combination of experimental procedures and mathematical modeling to provide new ways to manage infectious diseases.
A novel baculovirus-derived promoter with high activity in the baculovirus expression system

Editor rating: 9 / 10

Christopher Cooper –– Important for development of advanced baculovirus-mediated expression systems, both for people in the immediate field, and users of the technology.

Discussing these articles

150 days ago
Virus wars: using one virus to block the spread of another https://t.co/oLyUZU7z25

My article was published 1 year ago today in #OpenAccess journal @thePeerJ https://t.co/76F5Ee2ryJ // 1 year old soo cute XD cc @aloctavodia

Nature World News: "Virus Wars: Using "Good" Viral Agents to Combat Killer Viruses"
http://www.natureworldnews.com/articles/24839/20160706/virus-wars-using-good-viral-agents-combat-killer-viruses.htm

Engadget: "Researchers want to block HIV with a 'therapeutic' virus"
https://www.engadget.com/2016/07/05/researchers-want-to-block-hiv-with-a-therapeutic-virus/