Total of 48 results Filter on subject area
neuroscience
74 downloads
195 views

A common goal in biological sciences is to model a complex web of connections using a small number of interacting units. We present a general approach for dividing up elements in a spatial map based on their connectivity properties, allowing for the discovery of...

["Computational Biology","Neuroscience","Computational Science"]
doi:10.7717/peerj.784
49 downloads
151 views

LRRK2 was identified in 2004 as the causative protein product of the Parkinson’s disease locus designated PARK8. In the decade since then, genetic studies have revealed at least 6 dominant mutations in LRRK2 linked to Parkinson’s disease, alongside one associated...

["Biochemistry","Bioinformatics","Computational Biology","Neuroscience","Neurology"]
doi:10.7717/peerj.778
1 citation
111 downloads
246 views

Physical exercise is linked to individuals whose affect profiles are invariably positive and it induces anti-apoptotic and anti-excitotoxic effects, buttressing blood–brain barrier intactness in both healthy individuals and those suffering from disorders accompanying...

["Neuroscience","Global Health","Health Policy","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.694
104 downloads
229 views

A carefully controlled study allowed us to compare the sensitivity of ASL (arterial spin labeling) and BOLD (blood oxygen level dependent) fMRI for detecting the effects of the adenosine A2a antagonist tozadenant in Parkinson disease. The study compared the effect...

["Neuroscience","Neurology","Radiology and Medical Imaging"]
doi:10.7717/peerj.687
172 downloads
384 views

In humans and other mammals, drugs of abuse alter the function of biogenic amine pathways in the brain leading to the subjective experience of reward and euphoria. Biogenic amine pathways are involved in reward processing across diverse animal phyla, however whether...

["Animal Behavior","Entomology","Evolutionary Studies","Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.662
153 downloads
480 views

Reproducibility of biological data is a significant problem in research today. One potential contributor to this, which has received little attention, is the over complication of enzyme kinetic inhibition models. The over complication of inhibitory models stems...

["Biochemistry","Mathematical Biology","Neuroscience","Drugs and Devices","Pharmacology"]
doi:10.7717/peerj.649
117 downloads
287 views

Many recent comparative studies have addressed “episodic” memory in nonhuman animals, suggesting that birds, rodents, great apes, and others can remember their own behavior after at least a half-day delay. By contrast, despite numerous studies regarding long-term...

["Animal Behavior","Neuroscience"]
doi:10.7717/peerj.637
224 downloads
491 views

Billions of birds are estimated to be killed in window collisions every year, worldwide. A popular solution to this problem may lie in marking the glass with ultraviolet reflective or absorbing patterns, which the birds, but not humans, would see. Elegant as this...

["Animal Behavior","Conservation Biology","Ecology","Neuroscience","Coupled Natural and Human Systems"]
doi:10.7717/peerj.621
123 downloads
652 views

Having previously used functional MRI to map the response to a reward signal in the ventral caudate in awake unrestrained dogs, here we examined the importance of signal source to canine caudate activation. Hand signals representing either incipient reward or no...

["Animal Behavior","Neuroscience","Veterinary Medicine"]
doi:10.7717/peerj.596
186 downloads
328 views

Conventional structural Magnetic Resonance (MR) techniques can accurately identify brain tumors but do not provide exhaustive information about the integrity of the surrounding/embedded white matter (WM). In this study, we used Diffusion-Weighted (DW) MRI tractography...

["Neuroscience"]
doi:10.7717/peerj.497
164 downloads
525 views

Background. An apparent paradox in the field of neuropsychology is that people with atypical cerebral lateralization do not appear to suffer any cognitive disadvantage, yet atypical cerebral lateralization is more common in children and adults with developmental...

["Neuroscience","Cognitive Disorders","Pediatrics"]
doi:10.7717/peerj.507
187 downloads
462 views

Background. Unlike full reading, ‘skim-reading’ involves the process of looking quickly over information in an attempt to cover more material whilst still being able to retain a superficial view of the underlying content. Within this work, we specifically emulate...

["Bioinformatics","Neuroscience","Human\u2013Computer Interaction","Computational Science"]
doi:10.7717/peerj.483
177 downloads
423 views

The term autobiographical self has been used to refer to a mental state that permits reflection on self-identity and personality and the answer to related questions (Damasio, 1998). It requires the retrieval and integrated assembly of memories of facts and events...

["Neuroscience"]
doi:10.7717/peerj.481
187 downloads
268 views

Physiological and emotional states can affect our decision-making processes, even when these states are seemingly insignificant to the decision at hand. We examined whether posture and postural threat affect decisions in a non-related economic domain. Healthy young...

["Neuroscience","Kinesiology","Psychiatry and Psychology","Computational Science"]
doi:10.7717/peerj.475
209 downloads
272 views

Children with disruptive behavior disorders experience substantial social challenges; however, the factors that account for (i.e., mediate), or influence (i.e., moderate), peer problems are not well understood. This study tested whether symptoms of Oppositional...

["Neuroscience","Pediatrics","Psychiatry and Psychology"]
doi:10.7717/peerj.487

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