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In this study, we sequenced the genome of Pandoraea pnomenusa RB38 using Pacific Biosciences RSII (PacBio) Single Molecule Real Time (SMRT) sequencing technology. A pair of cognate luxI/R homologs was identified where the luxI homolog, ppnI, was found adjacent...

["Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.1225

Background. Neochelys franzeni Schleich, 1993 is the only pleurodire or side-necked turtle from the middle Eocene, Messel Pit (the first UNESCO, World Natural Heritage Site in Germany, since 1995). The original description of the species is based on two specimens...

["Biodiversity","Evolutionary Studies","Paleontology","Taxonomy","Zoology"]
doi:10.7717/peerj.1221

Gut-associated microbes of insects are postulated to provide a variety of nutritional functions including provisioning essential amino acids (EAAs). Demonstrations of EAA provisioning in insect-gut microbial systems, nonetheless, are scant. In this study, we investigated...

["Ecology","Entomology","Evolutionary Studies"]
doi:10.7717/peerj.1218

Several aspects of an individual’s appearance have been shown to predict personality and related behaviour. While some of these cues are grounded in biology (e.g., the human face), other aspects of a person’s appearance can be actively controlled (e.g., clothing)....

["Psychiatry and Psychology"]
doi:10.7717/peerj.1210

Background. Interleukin-6 (IL-6) is an important pro-inflammatory cytokine and has been implicated to play a role in the systemic inflammation of patients with chronic obstructive pulmonary disease (COPD). We conducted this meta-analysis to assess the association...

["Respiratory Medicine"]
doi:10.7717/peerj.1199

Intravenous levodopa has been used in a multitude of research studies due to its more predictable pharmacokinetics compared to the oral form, which is used frequently as a treatment for Parkinson’s disease (PD). Levodopa is the precursor for dopamine, and intravenous...

["Cardiology","Evidence Based Medicine","Neurology","Pharmacology","Translational Medicine"]
doi:10.7717/peerj.1198

Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions. Because of the complex nature of these communities,...

["Bioinformatics","Computational Biology","Genomics"]
doi:10.7717/peerj.1165

Background. The ischemic damage of the sinus node (SN) is a well known cause of cardiac arrhythmias and can be a consequence of any flow abnormality in the sinus node artery (SNA). Accordingly we aimed this retrospective study to: (1) evaluate the suitability of...

["Cardiology","Evidence Based Medicine","Hematology","Internal Medicine","Radiology and Medical Imaging"]
doi:10.7717/peerj.1156
1 download
2 views

The analysis of next-generation sequence (NGS) data is often a fragmented step-wise process. For example, multiple pieces of software are typically needed to map NGS reads, extract variant sites, and construct a DNA sequence matrix containing only single nucleotide...

["Bioinformatics"]
doi:10.7717/peerj-cs.20
6 downloads
43 views

Triple Modular Redundancy (TMR) is a common technique to protect memory elements for digital processing systems subject to radiation effects (such as in space, high-altitude, or near nuclear sources). This paper presents an approach to verify the correct implementation...

["Computer Aided Design","Computer Architecture","Embedded Computing"]
doi:10.7717/peerj-cs.21
6 downloads
53 views

Plasmonic assays are an important class of optical sensors that measure biomolecular interactions in real-time without the need for labeling agents, making them especially well-suited for clinical applications. Through the incorporation of nanoparticles and fiberoptics,...

["Computational Biology","Scientific Computing and Simulation","Software Engineering"]
doi:10.7717/peerj-cs.17
22 downloads
226 views

Yeasts play an important role in the biology of the fruit fly, Drosophila melanogaster. In addition to being a valuable source of nutrition, yeasts affect D. melanogaster behavior and interact with the host immune system. Most experiments investigating the role...

["Ecology","Entomology","Microbiology","Mycology"]
doi:10.7717/peerj.1116
18 downloads
160 views

Geographical patterns in body size have been described across a wide range of species, leading to the development of a series of fundamental biological rules. However, shape variables are less well-described despite having substantial consequences for organism...

["Biogeography","Ecology","Entomology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.1219
36 downloads
313 views

Backround. University rankings are getting very high international media attention, this holds particularly true for the Times Higher Education Ranking (THE) and the Shanghai Jiao Tong University’s Academic Ranking of World Universities Ranking (ARWU). We therefore...

["Science and Medical Education","Science Policy","Statistics"]
doi:10.7717/peerj.1217
18 downloads
113 views

The ability to regenerate is widespread in the animal kingdom, but the regenerative capacities and mechanisms vary widely. To understand the evolutionary history of the diverse regeneration mechanisms, the regeneration processes must be studied in early-evolved...

["Developmental Biology"]
doi:10.7717/peerj.1211

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