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Pawns is a programming language under development that supports algebraic data types, polymorphism, higher order functions and “pure” declarative programming. It also supports impure imperative features including destructive update of shared data structures via...

["Programming Languages"]
doi:10.7717/peerj-cs.22

Usability is a core construct of website evaluation and inherently defined as interactive. Yet, when analysing first impressions of websites, expected usability, i.e., before use, is of interest. Here we investigate to what extend ratings of expected usability...

["Human\u2013Computer Interaction","World Wide Web and Web Science"]
doi:10.7717/peerj-cs.19
2 views

In contrast to dominant mode of ecological transition in the evolution of marine mammals, different lineages of toothed whales (Odontoceti) have repeatedly invaded freshwater ecosystems during the Cenozoic era. The so-called ‘river dolphins’ are now recognized...

["Ecology","Evolutionary Studies","Marine Biology","Paleontology","Zoology"]
doi:10.7717/peerj.1227
2 views

As species become rare and approach extinction, purported sightings can be controversial, especially when scarce management resources are at stake. We consider the probability that each individual sighting of a series is valid. Obtaining these probabilities requires...

["Ecology","Mathematical Biology"]
doi:10.7717/peerj.1224
1 view

Cedecea neteri is a very rare human pathogen. We have isolated a strain of C. neteri SSMD04 from pickled mackerel sashimi identified using molecular and phenotypics approaches. Using the biosensor Chromobacterium violaceum CV026, we have demonstrated the presence...

["Genomics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.1216
1 view

In the Evolve and Resequence method (E&R), experimental evolution and genomics are combined to investigate evolutionary dynamics and the genotype-phenotype link. As other genomic approaches, this methods requires many replicates with large population sizes, which...

["Animal Behavior","Genetics"]
doi:10.7717/peerj.1214
3 views

Perilipins are lipid droplet surface proteins that contribute to fat metabolism by controlling the access of lipids to lipolytic enzymes. Perilipins have been identified in organisms as diverse as metazoa, fungi, and amoebas but strikingly not in nematodes. Here...

["Bioinformatics","Cell Biology","Genomics"]
doi:10.7717/peerj.1213
16 downloads
64 views

In this study, we sequenced the genome of Pandoraea pnomenusa RB38 using Pacific Biosciences RSII (PacBio) Single Molecule Real Time (SMRT) sequencing technology. A pair of cognate luxI/R homologs was identified where the luxI homolog, ppnI, was found adjacent...

["Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7717/peerj.1225
38 downloads
289 views

Background. Neochelys franzeni Schleich, 1993 is the only pleurodire or side-necked turtle from the middle Eocene, Messel Pit (the first UNESCO, World Natural Heritage Site in Germany, since 1995). The original description of the species is based on two specimens...

["Biodiversity","Evolutionary Studies","Paleontology","Taxonomy","Zoology"]
doi:10.7717/peerj.1221
23 downloads
168 views

Gut-associated microbes of insects are postulated to provide a variety of nutritional functions including provisioning essential amino acids (EAAs). Demonstrations of EAA provisioning in insect-gut microbial systems, nonetheless, are scant. In this study, we investigated...

["Ecology","Entomology","Evolutionary Studies"]
doi:10.7717/peerj.1218
17 downloads
322 views

Several aspects of an individual’s appearance have been shown to predict personality and related behaviour. While some of these cues are grounded in biology (e.g., the human face), other aspects of a person’s appearance can be actively controlled (e.g., clothing)....

["Psychiatry and Psychology"]
doi:10.7717/peerj.1210
15 downloads
123 views

Background. Interleukin-6 (IL-6) is an important pro-inflammatory cytokine and has been implicated to play a role in the systemic inflammation of patients with chronic obstructive pulmonary disease (COPD). We conducted this meta-analysis to assess the association...

["Respiratory Medicine"]
doi:10.7717/peerj.1199
6 downloads
111 views

Intravenous levodopa has been used in a multitude of research studies due to its more predictable pharmacokinetics compared to the oral form, which is used frequently as a treatment for Parkinson’s disease (PD). Levodopa is the precursor for dopamine, and intravenous...

["Cardiology","Evidence Based Medicine","Neurology","Pharmacology","Translational Medicine"]
doi:10.7717/peerj.1198
39 downloads
541 views

Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions. Because of the complex nature of these communities,...

["Bioinformatics","Computational Biology","Genomics"]
doi:10.7717/peerj.1165
6 downloads
107 views

Background. The ischemic damage of the sinus node (SN) is a well known cause of cardiac arrhythmias and can be a consequence of any flow abnormality in the sinus node artery (SNA). Accordingly we aimed this retrospective study to: (1) evaluate the suitability of...

["Cardiology","Evidence Based Medicine","Hematology","Internal Medicine","Radiology and Medical Imaging"]
doi:10.7717/peerj.1156

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