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30 downloads
39 views

We present a fast, validated, open-source toolkit for processing dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data. We validate it against the Quantitative Imaging Biomarkers Alliance (QIBA) Standard and Extended Tofts-Kety phantoms and find near...

["Radiology and Medical Imaging","Computational Science"]
doi:10.7717/peerj.909
51 downloads
127 views

Quantitative analysis of stable isotopes (SI) and, more recently, fatty acid profiles (FAP) are useful and complementary tools for estimating the relative contribution of different prey items in the diet of a predator. The combination of these two approaches, however,...

["Aquaculture, Fisheries and Fish Science","Bioinformatics","Conservation Biology","Ecology"]
doi:10.7717/peerj.920
18 downloads
28 views

Objectives. We wished to determine test re-test reliability and construct validity of the star-track test of manual dexterity.Design. Test re-test reliability was examined in a controlled study. Construct validity was tested in a blinded randomized crossover study.Setting....

["Drugs and Devices","Kinesiology","Surgery and Surgical Specialties","Statistics"]
doi:10.7717/peerj.917
13 downloads
14 views

The literature about possible cardiovascular consequences of diagnostic inertia in diabetes is scarce. We examined the influence of undetected high fasting blood glucose (FBG) levels on the cardiovascular risk and poor control of cardiovascular risk factors in...

["Diabetes and Endocrinology","Epidemiology","Nutrition","Public Health"]
doi:10.7717/peerj.914
17 downloads
66 views

Objective. We compared the precision of a search strategy designed specifically to retrieve randomized controlled trials (RCTs) and systematic reviews of RCTs with search strategies designed for broader purposes.Methods. We designed an experimental search strategy...

["Evidence Based Medicine","Science and Medical Education","Statistics","Computational Science"]
doi:10.7717/peerj.913
13 downloads
50 views

In protein evolution, due to functional and biophysical constraints, the rates of amino acid substitution differ from site to site. Among the best predictors of site-specific rates are solvent accessibility and packing density. The packing density measure that...

["Biophysics","Computational Biology","Evolutionary Studies","Mathematical Biology"]
doi:10.7717/peerj.911
10 downloads
10 views

To comprehensively evaluate the association between rs7517847 and rs2201841 polymorphisms in the Interleukin-23 (IL-23) receptor gene and ankylosing spondylitis (AS), a meta-analysis was performed. The Pubmed, Embase, MEDLINE, Cochrane, China National Knowledge...

["Genetics","Orthopedics","Rheumatology","Statistics"]
doi:10.7717/peerj.910
29 downloads
28 views

Results from large multicentre epidemiological studies suggest an association between the consumption of raw milk and a reduced incidence of allergy and asthma in children. Although the underlying mechanisms for this association are yet to be confirmed, researchers...

["Biotechnology","Genetics","Microbiology"]
doi:10.7717/peerj.888
12 downloads
33 views

GAF domains are a large family of regulatory domains, and a subset are found associated with enzymes involved in cyclic nucleotide (cNMP) metabolism such as adenylyl cyclases and phosphodiesterases. CyaB2, an adenylyl cyclase from Anabaena, contains two GAF domains...

["Biochemistry"]
doi:10.7717/peerj.882
19 downloads
14 views

Objectives. This study aimed to investigate the influences of N-acetyl cysteine (NAC) on cytotoxicity and mechanical properties of Poly-methylmethacrylate (PMMA) dental resins.Methods. Experimental PMMA resin was prepared by incorporating various concentrations...

["Dentistry"]
doi:10.7717/peerj.868
88 downloads
461 views

Sex differences in some preferences and motivations are well established, but it is unclear whether they persist in selective sub-populations, such as expert financial decision makers, top scientists, or elite athletes. We addressed this issue by studying competitiveness...

["Anthropology","Kinesiology","Psychiatry and Psychology"]
doi:10.7717/peerj.884
28 downloads
76 views

Background. Previous work has demonstrated that a commercial gaming electroencephalography (EEG) system, Emotiv EPOC, can be adjusted to provide valid auditory event-related potentials (ERPs) in adults that are comparable to ERPs recorded by a research-grade EEG...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.907
66 downloads
319 views

Originally identified as an ornithischian dinosaur, Crosbysaurus harrisae has been found in New Mexico, Arizona, and its type locality in Texas, as well as in North Carolina. The genus has been reassessed by other workers in light of reinterpretations about the...

["Paleontology"]
doi:10.7717/peerj.905
18 downloads
116 views

Comparing inferences among datasets generated using short read sequencing may provide insight into the concerted impacts of divergence, gene flow and selection across organisms, but comparisons are complicated by biases introduced during dataset assembly. Sequence...

["Bioinformatics","Evolutionary Studies","Genetics","Genomics","Molecular Biology"]
doi:10.7717/peerj.895
59 downloads
161 views

The teosinte branched1(tb1) gene is a major QTL controlling branching differences between maize and its wild progenitor, teosinte. The insertion of a transposable element (Hopscotch) upstream of tb1 is known to enhance the gene’s expression, causing reduced tillering...

["Agricultural Science","Ecology","Evolutionary Studies","Genetics"]
doi:10.7717/peerj.900

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