Peer-reviewed Articles

27 downloads
314 views

Background De novo transcriptome assembly of short reads is now a common step in expression analysis of organisms lacking a reference genome sequence. Several software packages are available to perform this task. Even if their results are of good quality it is...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.2988
28 downloads
342 views

Genomic heterogeneity of bacterial species is observed and studied in experimental evolution experiments and clinical diagnostics, and occurs as micro-diversity of natural habitats. The challenge for genome research is to accurately capture this heterogeneity with...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Microbiology"]
doi:10.7717/peerj.2997
42 downloads
228 views

Following study of the external morphology and its unmatched variability throughout ontogeny and a re-examination of selected morphological characters based on many specimens of diplomystids from Central and South Chile, we revised and emended previous specific...

["Aquaculture, Fisheries and Fish Science","Biodiversity","Conservation Biology","Taxonomy"]
doi:10.7717/peerj.2991
26 downloads
246 views

Plants and insects are key components of terrestrial ecosystems and insect herbivory is the most important type of interaction in these ecosystems. This study presents the first analysis of associations between plants and insects for the early Miocene Hindon Maar...

["Ecology","Paleontology","Plant Science"]
doi:10.7717/peerj.2985
30 downloads
267 views

The exoskeleton is an important source of characters for the taxonomy of Hydroidolina. It originates as epidermal secretions and, among other functions, protects the coenosarc of the polypoid stage. However, comparative studies on the exoskeletal tissue origin,...

["Cell Biology","Marine Biology","Taxonomy","Zoology","Histology"]
doi:10.7717/peerj.2964
22 downloads
163 views

Management of the few regulated ornamental fisheries relies on inadequate information about the life history of the target species. Herein, we investigated the reproductive biology of the most heavily traded marine invertebrate in the western Atlantic; the blue-legged...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Marine Biology","Zoology"]
doi:10.7717/peerj.3004
33 downloads
264 views

Background Colorectal cancer (CRC) is one of the leading cancers worldwide. Several studies have performed microarray data analyses for cancer classification and prognostic analyses. Microarray assays also enable the identification of gene signatures for molecular...

["Bioinformatics","Mathematical Biology","Molecular Biology","Oncology","Statistics"]
doi:10.7717/peerj.3003
20 downloads
191 views

Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by inhibiting differentiation...

["Dentistry","Immunology"]
doi:10.7717/peerj.2999
35 downloads
220 views

Type B trichothecenes, which pose a serious hazard to consumer health, occur worldwide in grains. These mycotoxins are produced mainly by three different trichothecene genotypes/chemotypes: 3ADON (3-acetyldeoxynivalenol), 15ADON (15-acetyldeoxynivalenol) and NIV...

["Bioinformatics","Mycology"]
doi:10.7717/peerj.2992
110 downloads
582 views

Background Protected areas, regarded today as a cornerstone of nature conservation, result from an array of multiple motivations and opportunities. We explored at global and regional levels the current distribution of protected areas along biophysical, human, and...

["Biogeography","Conservation Biology","Ecology"]
doi:10.7717/peerj.2989
17 downloads
78 views

Background Paroxysmal sympathetic hyperactivity (PSH) results and aggravates in secondary brain injury, which seriously affects the prognosis of severe traumatic brain injury patients. Although several studies have focused on the treatment of PSH, few have concentrated...

["Drugs and Devices","Emergency and Critical Care","Neurology"]
doi:10.7717/peerj.2986
31 downloads
218 views

Background Dental anxiety is a widespread problem in many populations. This problem can be a barrier to dental care and may lead to poor oral health. Dental anxiety may be related to psychological status. Aims The aim of the present study was to assess the levels...

["Dentistry","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2978
36 downloads
326 views

White-streaked grouper (Epinephelus ongus) is an important fisheries target and forms spawning aggregations at particular spawning grounds. The aims of the present study were to investigate the ecological characteristics of annual spawning aggregations such as...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Ecology","Marine Biology","Zoology"]
doi:10.7717/peerj.3000
30 downloads
716 views

Modafinil (2-((diphenylmethyl)sulfinyl)acetamide), a selective dopamine and norepinephrine transporter inhibitor, is most commonly prescribed for narcolepsy but has gained recent interest for treating a variety of disorders. Zebrafish (Danio rerio) are becoming...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Neuroscience","Pharmacology"]
doi:10.7717/peerj.2994
14 downloads
250 views

We created an easy-to-use device for operant licking experiments and another device that records environmental variables. Both devices use the Raspberry Pi computer to obtain data from multiple input devices (e.g., radio frequency identification tag readers, touch...

["Animal Behavior","Bioengineering","Neuroscience"]
doi:10.7717/peerj.2981

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