Preprints (not yet peer-reviewed)

61 downloads
152 views

Background: Multivariate statistical approaches (MSA), such as principal components analysis and multidimensional scaling, seek to uncover meaningful patterns within datasets by considering multiple response variables in a concerted fashion. Although these techniques...

["Environmental Sciences","Genomics","Marine Biology","Molecular Biology","Statistics"]
doi:10.7287/peerj.preprints.2200v1
75 downloads
313 views

Background. Feirana quadranus and Feirana taihangnica, two species of frogs inhabiting in waterbodies in the Qinling Mountains, China, are believed to be sister species that diverged 4.6 million years ago. In their sympatric area, morphological variations found...

["Evolutionary Studies","Molecular Biology","Taxonomy","Zoology","Statistics"]
doi:10.7287/peerj.preprints.2058v2
41 downloads
166 views

Background. In the early and late stages of cell reprogramming to induced pluripotent stem cells (iPSCs) ectopic expression of Oct4, Sox2, Klf4 and Myc (OSKM) aroused two peaks of transcriptional and epigenetic change respectively. However, it was relatively quiet...

["Bioinformatics","Cell Biology","Mathematical Biology","Molecular Biology","Statistics"]
doi:10.7287/peerj.preprints.1991v1
54 downloads
311 views

In personalized medicine, one major goal is the identification of yet unknown patient subgroups with specific gene or protein expression. Different subgroups can indicate different molecular subtypes of a disease. These subtypes might correlate with disease progression,...

["Bioinformatics","Computational Biology","Molecular Biology","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.1305v1
287 downloads
280 views

Skeletal muscle reaction to exercise is an essential are of research due to its ongoing prevalence in disease research and general health. It is well documented that under exercise conditions, biogenesis and autophagy increase. One main component of this pathway...

["Molecular Biology","Statistics"]
doi:10.7287/peerj.preprints.556v1
196 downloads
516 views

Genebanks increasingly use molecular markers for routine characterization of ex-situ collections and farmer managed diversity. The International Potato Center presently uses a SSR marker-kit to create molecular profiles for potato accessions. We identified a need...

["Anthropology","Biodiversity","Molecular Biology","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.522v1
173 downloads
453 views

Pairwise evolutionary distances are a model-based summary statistic for a set of molecular sequences. They represent the leaf-to-leaf path lengths of the underlying phylogenetic tree. Estimates of pairwise distances with overlapping paths covary because of shared...

["Computational Biology","Mathematical Biology","Molecular Biology","Computational Science","Statistics"]
doi:10.7287/peerj.preprints.387v2
1,655 downloads
1,556 views

As medical and molecular microbiologists who regularly read the scientific literature, it is our impression that many published papers contain data that is inappropriately presented and/or analysed. This is borne out by a number of studies which indicate that typically...

["Microbiology","Molecular Biology","Infectious Diseases","Statistics"]
doi:10.7287/peerj.preprints.92v1
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