Preprints (not yet peer-reviewed)

253 downloads
599 views

Lesion of the dopaminergic neurons of the nigrostriatal system is a key feature of Parkinson's disease (PD). Alpha-synuclein is a protein that is a major component of Lewy bodies, histopathological hallmarks of PD, and is involved in regulation of dopamine (DA)...

["Developmental Biology","Neuroscience","Neurology","Pathology"]
doi:10.7287/peerj.preprints.26547v2
84 downloads
512 views

Small interference RNA has been widely used to suppress gene expression. Three different short-hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal...

["Neuroscience","Neurology","Pathology"]
doi:10.7287/peerj.preprints.3117v1
491 downloads
354 views

Aging is mysterious with unknown managing patterns. A surprising finding on the tune mode of autophagy by S-nitrosylation is a distinctive step towards the interpretation of the mechanism underlying aging and age-related diseases. This commentary article will discuss,...

["Cell Biology","Diabetes and Endocrinology","Metabolic Sciences","Neurology","Pathology"]
doi:10.7287/peerj.preprints.121v1
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