Preprints (not yet peer-reviewed)

80 downloads
277 views

Taxonomic markers such as the 16S ribosomal RNA gene are widely used in microbial community analysis. A common first step in marker-gene analysis is grouping genes into clusters to reduce data sets to a more manageable size and potentially mitigate the effects...

["Bioinformatics","Ecology","Microbiology","Computational Science"]
doi:10.7287/peerj.preprints.2879v1
54 downloads
153 views

Colony counting to estimate colony forming units (CFUs) is a standard microbiology procedure used for determining the number of viable microbes in a system. Typically this process is done manually, which is time consuming, tedious, and sometimes error prone. Alternate...

["Microbiology","Medical Genetics","Computational Science"]
doi:10.7287/peerj.preprints.2792v1
25 downloads
107 views

Natural product libraries are important tools for drug discovery. However, until now, there has not been a system to allow projections of the potential number of hits from creating these libraries. The objective of this study was to develop a stochastic model system...

["Biodiversity","Biotechnology","Microbiology","Drugs and Devices","Computational Science"]
doi:10.7287/peerj.preprints.2734v1
184 downloads
1,028 views

Summary: Clustered regularly interspaced palindromic repeat (CRISPR) systems are prokaryotic adaptive immune systems against viral infection. CRISPR spacer sequences can provide valuable ecological insights by linking environmental viruses to microbial hosts. Despite...

["Bioinformatics","Genomics","Microbiology","Computational Science"]
doi:10.7287/peerj.preprints.2278v2
200 downloads
577 views

Background. Chromosome conformation capture, coupled with high throughput DNA sequencing in protocols like Hi-C and 3C-seq, has been proposed as viable means to generate data to resolve the genomes of microorganisms living in naturally occuring environments. Metagenomic...

["Bioinformatics","Computational Biology","Genomics","Microbiology","Computational Science"]
doi:10.7287/peerj.preprints.1974v2
1,217 downloads
625 views

Many microbial, fungal, or oomcyete populations violate assumptions for population genetic analysis because these populations are clonal or partially clonal. Furthermore, few tools exist that are specifically designed for analyzing data from clonal populations,...

["Bioinformatics","Genetics","Microbiology","Mycology","Computational Science"]
doi:10.7287/peerj.preprints.161v1
348 downloads
1,169 views

Supertree methods reconcile a set of phylogenetic trees into a single structure that is often interpreted as a branching history of species. A key challenge is combining conflicting evolutionary histories that are due to artifacts of phylogenetic reconstruction...

["Bioinformatics","Evolutionary Studies","Microbiology","Computational Science"]
doi:10.7287/peerj.preprints.18
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