Preprints (not yet peer-reviewed)

46 downloads
154 views

Development of drug resistance limits the effectiveness of anticancer treatments. Understanding the molecular mechanisms triggering this event in tumor cells may lead to improved therapeutic strategies. Here we used RNA-seq to compare the transcriptomes of an erythroleukemia...

["Molecular Biology","Hematology"]
doi:10.7287/peerj.preprints.2731v1
32 downloads
146 views

Background. Preanalytic factors such as time and temperature can have significant effects on laboratory test results. For example, ammonium concentration will increase 31% in blood samples stored at room temperature for 30 minutes before centrifugation. To reduce...

["Biochemistry","Veterinary Medicine","Emergency and Critical Care","Gastroenterology and Hepatology","Hematology"]
doi:10.7287/peerj.preprints.2398v1
67 downloads
102 views

Intermediate-risk AML is a group of heterogeneous disease, complete and accurate understanding of their molecular pattern are urgent. We downloaded gene expression profile from TCGA, and performed the differential gene expression analysis of 98 intermediate-risk...

["Hematology"]
doi:10.7287/peerj.preprints.1833v1
43 downloads
243 views

BACKGROUND: The ischemic damage of the sinus node (SN) is a well known cause of cardiac arrhythmias and can be a consequence of any flow abnormality in the sinus node artery (SNA). Accordingly we aimed this retrospective study to: 1. evaluate the suitability of...

["Cardiology","Evidence Based Medicine","Hematology","Internal Medicine","Radiology and Medical Imaging"]
doi:10.7287/peerj.preprints.1204v1
56 downloads
218 views

Introduction: Hospital readmission within 30 days of discharge is a target for health care cost savings through the medicare Value Based Purchasing initiative. Because of this focus, hospitals and health systems are investing considerable resources into the identification...

["Geriatrics","Health Policy","Hematology","Nutrition"]
doi:10.7287/peerj.preprints.1186v1
107 downloads
371 views

The governing nonlinear steady equations for oxygen transport in a microfluidic channel are solved analytically. The Lagrange inversion theorem is used which admits complete integrable solutions in the channel. Considering a cell-rich and cell free region with...

["Biophysics","Cell Biology","Computational Biology","Mathematical Biology","Hematology"]
doi:10.7287/peerj.preprints.1003v1
95 downloads
236 views

Obstetrical complications including preeclampsia, fetal growth restriction, preterm labor, preterm prelabor rupture of membranes and fetal demise are all the clinical endpoint of several underlying mechanisms (i.e. infection inflammation, thrombosis, endocrine...

["Gynecology and Obstetrics","Hematology"]
doi:10.7287/peerj.preprints.487v1
163 downloads
474 views

Backgroud: CCR6+ CD4+ regulatory T cells (CCR6+Tregs), a distinct Tregs subset, played an important role in various immune diseases. Recent evidence showed that microRNAs (miRNAs) are vital regulators in the function of immune cells. However, the potential role...

["Biotechnology","Cell Biology","Allergy and Clinical Immunology","Hematology","Immunology"]
doi:10.7287/peerj.preprints.471v2
538 downloads
348 views

Platelets expose phosphatidylserine (PS), a component of the prothrombinase complex, on the outer surface of the plasma membrane when activated. [ref 1] The prothrombinase complex catalyzes the conversion of prothrombin to thrombin, and it has been demonstrated...

["Anatomy and Physiology","Cardiology","Hematology"]
doi:10.7287/peerj.preprints.351v1
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