Preprints (not yet peer-reviewed)

31 downloads
99 views

Nowadays Mobile phones are becoming more popular in our daily lives. Mobile technology has a great effect on human life. Our daily tasks are dependent on mobile devices. Memory Management (MM), Security and Performance plays an important role in every handheld...

["Human-Computer Interaction","Computational Science"]
doi:10.7287/peerj.preprints.3344v1
4,416 downloads
25,480 views

The website Sci-Hub provides access to scholarly literature via full text PDF downloads. The site enables users to access articles that would otherwise be paywalled. Since its creation in 2011, Sci-Hub has grown rapidly in popularity. However, until now, the extent...

["Bioinformatics","Legal Issues","Science and Medical Education","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.3100v2
19 downloads
113 views

Network diffusion approaches are frequently used for identifying the relevant disease genes and for prioritizing the genes for drug sensitivity predictions. Majority of these studies rely on networks representing a single type of information. However, using multiplex...

["Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3339v1
20 downloads
77 views

Celiac disease is a chronic condition, which can be described as inflammatory and autoimmune. The well-known treatment is a lifelong gluten-free diet, but it can be not totally effective for a high percentage of the patients. The aim of this work is to approach...

["Bioinformatics","Biotechnology","Computational Biology","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.3315v1
32 downloads
93 views

Coarse-grained simulations enable the study of membrane proteins in the context of their native environment but require reliable parameters. The CgProt force field is assessed by comparing the potentials of mean force for sidechain insertion in a DOPC bilayer to...

["Biophysics","Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3306v1
25 downloads
268 views

Background. The number of individuals of each species in a given location forms the basis for many sub-fields of ecology and evolution. Data on individuals, including which species, and where they're found can be used for a large number of research questions. Global...

["Bioinformatics","Ecology","Computational Science"]
doi:10.7287/peerj.preprints.3304v1
17 downloads
103 views

Recently, we showed that the controlled NOT function is a permutation that cannot be inverted in subexponential time in the worst case [Quantum Information Processing. 16:149 (2017)]. Here, we show that such a condition can provoke biased interpretations from Bell’s...

["Computational Science"]
doi:10.7287/peerj.preprints.3302v1
41 downloads
180 views

It is now becoming feasible to determine the composition of an individual gut microbiota (gut microflora), as well as the individual genome. In addition, whole genome scale metabolic models (GEMs) exist for a range of bacteria, and also for human. In principle...

["Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3267v2
41 downloads
208 views

Exogenous sequence contamination presents a challenge in first-draft genomes because it can lead to non-contiguous, chimeric assembled sequences. This can mislead downstream analyses reliant on synteny, such as linkage-based analyses. Recently, the Mojave Desert...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3266v3
14 downloads
109 views

The leading cause of permanent disability in developed countries is due to neurological injuries, such as stroke. While physical rehabilitation therapy is indispensable for treating neurological disabilities, repetitive and high intensity therapies place high physical...

["Human-Computer Interaction","Computational Science"]
doi:10.7287/peerj.preprints.3255v2
25 downloads
131 views

Finding and enumerating common molecular substructures is an important task in cheminformatics, where small molecules are often modeled as molecular graphs. We introduce the problem of enumerating all maximal k-common molecular fragments of a pair of molecular...

["Bioinformatics","Computational Science"]
doi:10.7287/peerj.preprints.3250v1
61 downloads
145 views

Horizontal gene transfer (HGT) is a powerful mechanism that allows bacteria to directly transfer long stretches of genomic sequence from one individual to another. The transfer of antimicrobial resistance genes is a prominent example of HGT events in the context...

["Bioinformatics","Computational Biology","Public Health","Computational Science"]
doi:10.7287/peerj.preprints.3248v1
20 downloads
182 views

Computational biology is rapidly advancing thanks to the many new tools developed and published each month. A systematic benchmarking practice would help biomedical researchers leverage this technological expansion to optimize their projects. Several aspects of...

["Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3236v1
63 downloads
189 views

Standard procedures for NGS data analysis involve a pre-processing step of reads quality assessment, followed by the alignment of the filtered reads to a reference genome. Typically the amount of reads that correctly maps to the specific reference genome ranges...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3230v1
238 downloads
638 views

RNA sequencing (RNA-Seq) is a powerful technique for thegene-expression profiling of organisms that uses the capabilities of next-generation sequencing technologies.Developing gene-expression-based classification algorithms is an emerging powerful method for diagnosis,...

["Bioinformatics","Genomics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2761v2
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