Preprints (not yet peer-reviewed)

78 downloads
145 views

Generating heatmaps of genes datasets have been known to be a graphical representation of data where the individual values contained in a matrix are represented as colors. Herein, we describe AFCMHeatMap a shiny web App that integrates quantitative interaction...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.2961v1
120 downloads
636 views

Knockout Sudoku is a method for the construction of whole-genome knockout collections for a wide range of microorganisms with as little as 3 weeks of dedicated labor and at a cost of approximately $10,000. The method uses manual 4-dimensional combinatorial pooling,...

["Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.2294v1
149 downloads
215 views

Motivations. Building the Burrows-Wheeler transform (BWT) and computing the Lempel-Ziv parsing (LZ77) of huge collections of genomes is becoming an important task in bioinformatic analyses as these datasets often need to be compressed and indexed prior to analysis....

["Bioinformatics","Computational Biology","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.2176v1
42 downloads
235 views

Objective: Bringing together genomics, transcriptomics, proteomics, and other –omics technologies is an important step towards developing highly personalized medicine. However, instrumentation has advances far beyond expectations and now we are able to generate...

["Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.1021v1
230 downloads
734 views

Scaffolding errors and incorrect traversals of the de Bruijn graph during de novo assembly can result in large scale misassemblies in draft genomes. Nextera mate pair sequencing data provide additional information to resolve assembly ambiguities during scaffolding....

["Bioinformatics","Genetics","Genomics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.747v1
1,215 downloads
625 views

Many microbial, fungal, or oomcyete populations violate assumptions for population genetic analysis because these populations are clonal or partially clonal. Furthermore, few tools exist that are specifically designed for analyzing data from clonal populations,...

["Bioinformatics","Genetics","Microbiology","Mycology","Computational Science"]
doi:10.7287/peerj.preprints.161v1
698 downloads
664 views

The Roche 454 GS Junior sequencing platform allows locus-specific DNA methylation analysis using deep bisulfite amplicon sequencing. However, bisulfite-converted DNA reads may contain long T homopolymers, and the main sources of errors on pyrosequencing platforms...

["Bioinformatics","Computational Biology","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.122v2
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