Preprints (not yet peer-reviewed)

117 downloads
408 views

Introduction Age is the primary risk factor for major human chronic diseases, including cardiovascular disorders, cancer, type 2 diabetes, and neurodegenerative diseases. Chronic, low-grade, systemic inflammation is associated with aging and the progression of...

["Computational Biology","Microbiology","Geriatrics","Immunology"]
doi:10.7287/peerj.preprints.1754v1
157 downloads
284 views

Biomedical knowledge is growing exponentially; however, meta-knowledge around the data is often lacking. PubMed is a database comprising more than 21 million citations for biomedical literature from MEDLINE and additional life science journals dating back to the...

["Bioinformatics","Computational Biology","Cardiology","Evidence Based Medicine","Immunology"]
doi:10.7287/peerj.preprints.1446v1
321 downloads
1,089 views

Classification of antibody Complementarity-Determining Region (CDR) conformations is an important step that drives antibody modelling and engineering, prediction from sequence, directed mutagenesis and induced-fit studies, and allows inferences on sequence-to-structure...

["Bioinformatics","Computational Biology","Molecular Biology","Immunology"]
doi:10.7287/peerj.preprints.291v3
150 downloads
918 views

The accurate prediction of the conformation of Complementarity-Determining Regions (CDRs) is important in modelling antibodies for protein engineering applications. Specifically, the Canonical paradigm has proved successful in predicting the CDR conformation in...

["Bioinformatics","Computational Biology","Molecular Biology","Immunology"]
doi:10.7287/peerj.preprints.292v3
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