Preprints (not yet peer-reviewed)

35 downloads
122 views

Clinical bioinformatics is an emerging field in diagnostic genetics laboratories that are harnessing next-generation sequencing technologies to improve patient care. This document provides guidance for the development and validation of software used for delivery...

["Bioinformatics","Genomics","Science Policy"]
doi:10.7287/peerj.preprints.2996v1
120 downloads
218 views

The “reproducibility crisis” has been a highly visible source of scientific controversy and dispute. Here, I propose and review several avenues for identifying and prioritizing research studies for the purpose of targeted validation. Of the various proposals discussed,...

["Bioinformatics","Evidence Based Medicine","Health Policy","Translational Medicine","Science Policy"]
doi:10.7287/peerj.preprints.2830v1
39 downloads
286 views

This document is an open response to the NIH Request for Information (RFI): Strategies for NIH Data Management, Sharing, and Citation, Notice Number: NOT-OD-17-015, written by the leaders of the FORCE11 Software Citation Working Group from its inception in mid-2015...

["Bioinformatics","Science Policy"]
doi:10.7287/peerj.preprints.2640v1
467 downloads
447 views

“Open access” has become a central theme of journal reform in academic publishing. In this article, I examine the consequences of an important technological loophole in which publishers can claim to be adhering to the principles of open access by releasing articles...

["Bioinformatics","Evidence Based Medicine","Health Policy","Translational Medicine","Science Policy"]
doi:10.7287/peerj.preprints.2566v1
1,274 downloads
559 views

Despite the increasing availability of chemicals, the number of New Drug Approvals (NDA) from the Food and Drug Administration (FDA) remains unchanged. The number of chemical structures available online via web-based open source applications will reach the symbolic...

["Bioinformatics","Public Health","Translational Medicine","Science Policy","Statistics"]
doi:10.7287/peerj.preprints.813v1
299 downloads
696 views

Open science is increasingly gaining attention in recent years. In this mini-review, we briefly discuss and summarize the reasons of introducing open science into academic publications for scientists. We argue that open-source software (like R and Python software)...

["Bioinformatics","Computational Science","Legal Issues","Science and Medical Education","Science Policy"]
doi:10.7287/peerj.preprints.235v1
399 downloads
1,087 views

The 14th annual Bioinformatics Open Source Conference (BOSC) was held in Berlin in July 2013, bringing together over 100 bioinformatics researchers, developers and users of open source software. Since its inception in 2000, BOSC has been organised as a Special...

["Bioinformatics","Computational Biology","Genomics","Computational Science","Science Policy"]
doi:10.7287/peerj.preprints.83v1
162 downloads
840 views

Recently introduced funding agency policies seek to increase the availability of data from individual published studies for reuse by the research community at large. The success of such policies can be measured both by data input (“is useful data being made available?”)...

["Bioinformatics","Science Policy"]
doi:10.7287/peerj.preprints.14
2,079 downloads
7,897 views

BACKGROUND: Attribution to the original contributor upon reuse of published data is important both as a reward for data creators and to document the provenance of research findings. Previous studies have found that papers with publicly available datasets receive...

["Bioinformatics","Science Policy"]
doi:10.7287/peerj.preprints.1
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