Preprints (not yet peer-reviewed)

11 downloads
92 views

The Rickettsiales-like prokaryote - Candidatus Xenohaliotis californiensis (Ca. Xc) – has decimated black abalone populations along the Pacific coast of North America. White abalone, – Haliotis sorenseni – are also susceptible and nearly extinct in the wild due...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Microbiology","Virology","Natural Resource Management"]
doi:10.7287/peerj.preprints.3351v1
21 downloads
231 views

Current research posits that all multicellular organisms live in symbioses with associated microorganisms and form so-called metaorganisms or holobionts. Cnidarian metaorganisms are of specific interest given that stony corals provide the foundation of the globally...

["Bioinformatics","Genomics","Virology","Biosphere Interactions"]
doi:10.7287/peerj.preprints.3343v1
23 downloads
189 views

Background. Enteroviruses are small non-enveloped viruses with (+) ssRNA genome with one open reading frame. Enterovirus protein 3C (or 3CD for some species) binds the replicative element oriL to initiate replication. The replication of enteroviruses features low...

["Evolutionary Studies","Genomics","Virology"]
doi:10.7287/peerj.preprints.3153v2
24 downloads
103 views

Lineage determination is an important part of the analysis of viral sequence data. Previously this has depended on phylogenetic analysis in order to identify distinct clades within the phylogenetic trees. This method is time consuming and dependent on a set of...

["Bioinformatics","Virology"]
doi:10.7287/peerj.preprints.3166v1
31 downloads
127 views

Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described. TRAS family transposons encoding an ORF2 protein, which comprised all typical functional...

["Entomology","Genomics","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.3101v1
82 downloads
164 views

Background. The Ebola Virus Disease (EVD) is a highly infectious disease that has claimed over 25,000 cases in the past 50 years. While many past outbreaks of EVD resulted in relatively few incidents, the 2014 outbreak in West Africa was the most deadly occurrence...

["Virology","Epidemiology","Infectious Diseases","Statistics"]
doi:10.7287/peerj.preprints.3021v1
14 downloads
139 views

Live attenuated viral vaccines provide the most robust and longest lasting immune response. Yet designing them a priori to have reduced growth capacity and also to be robust to evolutionary reversion can be challenging. On the one hand, genome editing methods now...

["Evolutionary Studies","Virology"]
doi:10.7287/peerj.preprints.3001v1
30 downloads
229 views

Influenza A viruses cause an annual highly contagious respiratory disease in humans, and are responsible for periodic human pandemics that have high mortality rates. Pandemic influenza A viruses can result from reassortment of one or more gene segments between...

["Evolutionary Studies","Microbiology","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.3000v1
68 downloads
369 views

Viruses could have originated from the frantic competition to survive among primitive life forms. This is the result of this new hypothesis which proposes that viruses could have originated as remnants of the disintegration of primitive microorganisms. The disintegration...

["Evolutionary Studies","Virology"]
doi:10.7287/peerj.preprints.1801v2
64 downloads
246 views

With the emergence of Next Generation Sequencing, major advances were made with regard to identifying viruses in natural environments. However, bioinformatical research on viruses is still limited because of the low amounts of viral DNA that can be obtained for...

["Biodiversity","Genomics","Microbiology","Virology"]
doi:10.7287/peerj.preprints.2912v1
20 downloads
139 views

The identification of Parrot bornaviruses in psittacine birds with proventricular dilatation disease (PDD) has not been sufficient to explain the pathogenesis of this fatal disease since not all infected birds develop clinical signs. One hypothesis suggests that...

["Veterinary Medicine","Virology","Pathology"]
doi:10.7287/peerj.preprints.2852v1
61 downloads
230 views

Background: Geminivirus (family Geminiviridae) is a prevalent plant virus that imperils agriculture globally, causing serious damage to the livelihood of farmers, particularly in developing countries. The virus evolves rapidly, attributing to its single-stranded...

["Agricultural Science","Bioinformatics","Genomics","Virology"]
doi:10.7287/peerj.preprints.2705v1
63 downloads
233 views

Diseases of marine mammals can be difficult to diagnose because of the life history and protected status of these animals. Stranded marine mammals have been a particularly useful resource to discover and comprehend the diseases that plague these top predators....

["Aquaculture, Fisheries and Fish Science","Marine Biology","Microbiology","Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2457v1
65 downloads
172 views

An acute outbreak of porcine hemagglutinating encephalomyelitis virus (PHEV) infection in piglets, characterized with neurological symptoms, vomiting, diarrhea, and wasting, occurred in China. Coronavirus-like particles were observed in the homogenized tissue suspensions...

["Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2351v1
92 downloads
287 views

Background – Corns are hard protuberances that occur on the digital footpads of Greyhound dogs. The cause of these lesions is unknown and there is little information about them in the veterinary literature. We received anecdotal examples of dog to dog spread of...

["Molecular Biology","Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2290v1
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