Preprints (not yet peer-reviewed)

21 downloads
126 views

Background: Geminivirus (family Geminiviridae) is a prevalent plant virus that imperils agriculture globally, causing serious damage to the livelihood of farmers, particularly in developing countries. The virus evolves rapidly, attributing to its single-stranded...

["Agricultural Science","Bioinformatics","Genomics","Virology"]
doi:10.7287/peerj.preprints.2705v1
24 downloads
138 views

Diseases of marine mammals can be difficult to diagnose because of the life history and protected status of these animals. Stranded marine mammals have been a particularly useful resource to discover and comprehend the diseases that plague these top predators....

["Aquaculture, Fisheries and Fish Science","Marine Biology","Microbiology","Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2457v1
54 downloads
119 views

An acute outbreak of porcine hemagglutinating encephalomyelitis virus (PHEV) infection in piglets, characterized with neurological symptoms, vomiting, diarrhea, and wasting, occurred in China. Coronavirus-like particles were observed in the homogenized tissue suspensions...

["Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2351v1
81 downloads
225 views

Background – Corns are hard protuberances that occur on the digital footpads of Greyhound dogs. The cause of these lesions is unknown and there is little information about them in the veterinary literature. We received anecdotal examples of dog to dog spread of...

["Molecular Biology","Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.2290v1
148 downloads
447 views

Zika virus (ZIKV), a mosquito borne disease, has been linked to congenital anomalies in humans. Recent outbreaks of ZIKV have caused the scientific community to focus on this previously neglected pathogen. Information regarding phosphorylation potential of ZIKV...

["Bioinformatics","Computational Biology","Virology"]
doi:10.7287/peerj.preprints.2047v2
36 downloads
263 views

The baculovirus expression vector system (BEVS) has been widely used to produce a large number of recombinant proteins, and is becoming one of the most powerful, robust, and cost-effective systems for the production of eukaryotic proteins. Nevertheless, as in any...

["Biotechnology","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.2024v1
249 downloads
277 views

A major limitation with traditional phage preparations is the variability in titer, salts, and bacterial contaminants between successive propagations. Here we introduce the Phage On Tap (PoT) protocol for the quick and efficient preparation of homogenous bacteriophage...

["Microbiology","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.1966v1
89 downloads
305 views

Members of the Caliciviridae family of positive sense RNA viruses cause a wide range of diseases in both humans and animals. The detailed characterization of the calicivirus life cycle had been hampered due to the lack of robust cell culture systems and experimental...

["Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.1960v1
89 downloads
422 views

The advent of metagenomic methods to sequence DNA directly from an environment has revolutionized viral ecology, making it possible to “see” natural viral communities that could not be previously studied through culture. This technological leap has enabled further...

["Bioinformatics","Genomics","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.1901v1
41 downloads
184 views

Viruses could have originated from the frantic competition to survive among the primitive life forms of the old ages. This is the result of this new hypothesis which proposes that viruses could have originated as remnants of primitive microorganisms disintegration....

["Virology"]
doi:10.7287/peerj.preprints.1801v1
92 downloads
822 views

The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cpro performs most of the proteolytic processing of the polyprotein expressed from the single open reading frame in the RNA...

["Agricultural Science","Biochemistry","Microbiology","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.1750v1
129 downloads
491 views

In July 2014, we observed premature feather loss (PFL) among non-sibling, common tern Sterna hirundo chicks between 2 and 4 weeks of age at Gull Island in northern Lake Ontario, Canada. Rarely observed in wild birds, to our knowledge PFL has not been recorded in...

["Ecology","Marine Biology","Toxicology","Virology","Public Health"]
doi:10.7287/peerj.preprints.1196v2
69 downloads
345 views

The H5N8 influenza subtype is a relatively new highly pathogenic avian influenza. Until the recent Korean outbreak of H5N8 the viral subtype had only been detected sporadically. This paper looks at the multiple reassortment events between H5 hemagglutinin and N8...

["Bioinformatics","Evolutionary Studies","Virology"]
doi:10.7287/peerj.preprints.1489v1
138 downloads
348 views

Sacbrood virus (SBV) and deformed wing virus (DWV) are evolutionarily related positive-strand RNA viruses, members of the Iflavirus group, which infect the honeybee Apis mellifera, but have strikingly different levels of virulence when transmitted orally. Honeybee...

["Entomology","Genomics","Microbiology","Parasitology","Virology"]
doi:10.7287/peerj.preprints.1405v1
97 downloads
177 views

Vertebrate mothers transfer diverse compounds to developing embryos that can affect their development and final phenotype (i.e. maternal effects). However, the way such effects modulate offspring phenotype, in particular their immunity remains unclear. To test...

["Evolutionary Studies","Virology","Zoology","Immunology","Infectious Diseases"]
doi:10.7287/peerj.preprints.1380v1
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