Preprints (not yet peer-reviewed)

31 downloads
108 views

Worldwide concern about the impacts of endocrine disrupting compounds on both human and environmental health has led to implementation of multiple screening and testing programs. In most cases these programs have focused on impacts to the estrogen, androgen and...

["Computational Biology","Toxicology","Science Policy"]
doi:10.7287/peerj.preprints.2605v1
35 downloads
109 views

In response to the requirements of the US EPA’s Endocrine Disruptor Screening Program, Tier 1 assays have been performed with a number of pesticides over the past several years. These assays are designed to be used in concert as a screen for potential interactions...

["Environmental Sciences","Toxicology","Science Policy"]
doi:10.7287/peerj.preprints.2596v1
63 downloads
124 views

Water quality benchmarks are developed by many jurisdictions worldwide with the general goal of identifying concentrations that protect aquatic communities. Imidacloprid is a widely-used neonicotinoid insecticide for which benchmark values vary widely between North...

["Agricultural Science","Ecosystem Science","Environmental Sciences","Toxicology"]
doi:10.7287/peerj.preprints.2584v1
74 downloads
100 views

Presentations in session one of the Society of Environmental Toxicology and Chemistry (SETAC) North America Focused Topic Meeting: Endocrine Disruption (February 4 – 6, 2014) described where the science and the regulations have arrived and identified the key challenges...

["Ecology","Environmental Sciences","Genomics","Toxicology","Histology"]
doi:10.7287/peerj.preprints.2583v1
98 downloads
92 views

Approaches to assessing endocrine disruptors (EDs) differ across the globe, with some regulatory environments using a hazard-based approach, while others employ risk-based analyses. In session four of the Society of Environmental Toxicology and Chemistry (SETAC)...

["Environmental Sciences","Toxicology","Science Policy"]
doi:10.7287/peerj.preprints.2580v1
29 downloads
63 views

This special series of six papers (this introductory paper and 5 other papers) is about the Focused Topic Meeting on Endocrine Disruption Chemical Testing; Risk Assessment Approaches and Implications (4 – 6 February, 2014, Raleigh, North Carolina). The workshop...

["Ecology","Environmental Sciences","Genomics","Toxicology"]
doi:10.7287/peerj.preprints.2578v1
176 downloads
1,842 views

Herbicide use is among the most criticized aspects of modern farming operations, especially in response to widespread adoption of genetically-engineered (GE) herbicide-resistant crops. Many previous analyses of herbicide use have relied on flawed metrics in an...

["Agricultural Science","Environmental Sciences","Plant Science","Toxicology"]
doi:10.7287/peerj.preprints.2540v1
79 downloads
77 views

The focus of this session was on the proposed USEPA Endocrine Disruption Screening Program (EDSP) Tier 2 testing protocols. Tier 2 tests have been developed to evaluate the potential impacts of endocrine disrupting chemicals (EDCs) over the life cycle across organisms...

["Ecosystem Science","Toxicology"]
doi:10.7287/peerj.preprints.2527v1
23 downloads
168 views

The study of subjective, first-person experience is a topic with both philosophical and practical implications. In this article, I discuss the value of collecting a critical mass of prose or verbal descriptions of introspectively determined, subjective effects...

["Toxicology","Evidence Based Medicine","Neurology","Pharmacology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.2424v1
35 downloads
104 views

Snakebite envenomings represent a neglected public health issue in many parts of the rural tropical world. Animal-derived antivenoms have existed for more than a hundred years and are effective in neutralizing snake venom toxins when timely administered. However,...

["Bioinformatics","Biotechnology","Toxicology","Immunology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2364v1
51 downloads
136 views

This study examined developmental toxicity of different mercury compounds, including some used in traditional medicines. Medaka (Oryzias latipes) embryos were exposed to 0.001-10 μM concentrations of MeHg, HgCl2, α-HgS (Zhu Sha), and β-HgS (Zuotai) from stage 10...

["Aquaculture, Fisheries and Fish Science","Developmental Biology","Toxicology","Pharmacology","Public Health"]
doi:10.7287/peerj.preprints.2329v1
143 downloads
371 views

The Brazilian Pampa biome is currently under constant threat due to increase of agriculture and improper management of urban effluents. Studies with focus on the assessment of impacts caused by human activities in this biome are scarce. In the present study we...

["Biochemistry","Ecology","Environmental Sciences","Toxicology"]
doi:10.7287/peerj.preprints.776v2
89 downloads
154 views

N-Acetyl-p-Aminophenol (APAP), aka acetaminophen, is the most commonly used over-the counter analgesic and antipyretic medication. However, its overdose leads to both liver and kidney damage. APAP-induced toxicity is considered as one of the primary causes of acute...

["Food Science and Technology","Neuroscience","Toxicology","Pathology","Pharmacology"]
doi:10.7287/peerj.preprints.2063v1
40 downloads
195 views

A lot of literature show that social isolation stress could be a key reason that leads to cognitive deficits for both humans and rodent models; however, the detailed mechanisms are still not clear completely. ADAR1 (Adenosine deaminase acting on RNA) is an enzyme...

["Animal Behavior","Biochemistry","Neuroscience","Toxicology","Pharmacology"]
doi:10.7287/peerj.preprints.1997v1
448 downloads
1,014 views

The Zika virus is the primary suspect in the large increase in microcephaly cases in 2015-6 in Brazil, however its role is unconfirmed despite individual cases of viral infections found in neural tissue. Here we consider the alternative that the insecticide pyriproxyfen,...

["Toxicology","Pharmacology","Public Health","Science Policy"]
doi:10.7287/peerj.preprints.1959v1
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