Preprints (not yet peer-reviewed)

11 downloads
159 views

The secretory pathway in Plasmodium falciparum has evolved to transport proteins to the host cell membrane and to an endosymbiotic organelle, the apicoplast. The latter can occur via the ER or the ER-Golgi route. Here, we study these three routes using proteins...

["Cell Biology","Parasitology"]
doi:10.7287/peerj.preprints.2813v2
24 downloads
111 views

American trypanosomiasis is a chronic and endemic disease, which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions....

["Biochemistry","Genomics","Molecular Biology","Parasitology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2782v1
31 downloads
167 views

Trypanosoma brucei brucei (TBB) belongs to the unicellular parasitic protozoa organisms, specifically to the Trypanosoma genus of the Trypanosomatidae class. A variety of different vertebrate species can be infected by TBB including humans and animals. Under particular...

["Biochemistry","Bioinformatics","Computational Biology","Evolutionary Studies","Parasitology"]
doi:10.7287/peerj.preprints.2775v1
87 downloads
163 views

Phytochemicals produced by plants, including at flowers, function in protection against plant diseases, and have a long history of use against trypanosome infection. Floral nectar and pollen, the sole food sources for many species of insect pollinators, contain...

["Ecology","Entomology","Parasitology","Plant Science","Infectious Diseases"]
doi:10.7287/peerj.preprints.2730v1
56 downloads
506 views

Despite high success rate in treating human Strongyloides infection with ivermectin, there is no consensus about the treatment of hyperinfection by helminths of the genus Strongyloides in immunocompromised people. Chances of survival of patients suffering from...

["Computational Biology","Mathematical Biology","Parasitology","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.2399v1
137 downloads
352 views

Communities of symbiotic microbes obtained from the environment are an integral component of animal fitness and ecology. Thus a general and practical understanding of the processes that drive microbiome assembly and structure are paramount to understanding animal...

["Biodiversity","Biogeography","Ecology","Microbiology","Parasitology"]
doi:10.7287/peerj.preprints.2266v1
205 downloads
317 views

Background. With 214 million cases and 438,000 deaths in 2015, malaria remains one of the deadliest infectious diseases in tropical countries. Several species of the protozoan Plasmodium cause malaria. However, almost all the fatalities are due to Plasmodium falciparum,...

["Parasitology","Global Health","Immunology","Infectious Diseases"]
doi:10.7287/peerj.preprints.1918v1
29 downloads
232 views

Many major human infectious diseases are transmitted via bodily products such as feces, blood, semen, and saliva. Such contaminants are also known disgust elicitors among humans. From an evolutionary perspective, revulsion in humans is hypothesized to have evolved...

["Animal Behavior","Anthropology","Ecology","Evolutionary Studies","Parasitology"]
doi:10.7287/peerj.preprints.1851v1
198 downloads
373 views

Symbiont occurrence is influenced by host occurrence and vice versa, which leads to correlations in host-symbiont distributions at multiple levels. Interactions between co-infecting symbionts within host individuals can cause correlations in the abundance of two...

["Biodiversity","Ecology","Parasitology","Infectious Diseases","Statistics"]
doi:10.7287/peerj.preprints.1502v1
139 downloads
366 views

Sacbrood virus (SBV) and deformed wing virus (DWV) are evolutionarily related positive-strand RNA viruses, members of the Iflavirus group, which infect the honeybee Apis mellifera, but have strikingly different levels of virulence when transmitted orally. Honeybee...

["Entomology","Genomics","Microbiology","Parasitology","Virology"]
doi:10.7287/peerj.preprints.1405v1
318 downloads
244 views

Understanding the genetic variation of the Plasmodium parasites could play an important role in controlling and preventing this lethal infection. Inter simple sequence repeat (ISSR) markers have successfully been tested for investigating the genetic diversity of...

["Biodiversity","Biotechnology","Evolutionary Studies","Molecular Biology","Parasitology"]
doi:10.7287/peerj.preprints.1253v1
64 downloads
257 views

Thermal physiology of entomopathogenic nematodes (EPN) is a critical aspect of field performance and fitness. Thermal limits for survival and activity, and the ability of these limits to adjust (i.e. show phenotypic flexibility) depending on recent thermal history,...

["Agricultural Science","Entomology","Parasitology"]
doi:10.7287/peerj.preprints.1152v1
159 downloads
506 views

The American brine shrimp Artemia franciscana is invasive in the Mediterranean region where it has displaced native species (the sexual A. salina, and the clonal A. parthenogenetica) from many salt pond complexes. Artemia populations are parasitized by numerous...

["Biodiversity","Ecology","Parasitology","Zoology"]
doi:10.7287/peerj.preprints.975v1
1,129 downloads
346 views

Background. Blacklegged ticks (Ixodes scapularis) are important disease vectors in the United States, known to transmit a variety of pathogens to humans, including bacteria, protozoa, and viruses. Their importance as a disease vector necessitates reliable and comparable...

["Entomology","Evolutionary Studies","Microbiology","Parasitology","Infectious Diseases"]
doi:10.7287/peerj.preprints.842v1
178 downloads
866 views

Crustacean intersexuality is widespread and often linked to infection by sex-distorting parasites. However, unlike vertebrate intersexuality, its association with sexual dysfunction is unclear and remains a matter of debate. The ‘Demon Shrimp’, Dikerogammarus haemobaphes,...

["Ecology","Parasitology","Zoology"]
doi:10.7287/peerj.preprints.687v2
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