Preprints (not yet peer-reviewed)

143 downloads
565 views

Synapsida, the clade including therapsids and thus also mammals, is one of the two major branches of amniotes. Organismal design, with modularity as a concept, offers insights into the evolution of therapsids, a group that experienced profound anatomical transformations...

["Developmental Biology","Evolutionary Studies","Neuroscience","Paleontology","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.2313v2
11 downloads
69 views

It is now widely accepted that oligomers consisting of Aβ peptide are the cytotoxic species contributing mostly to the development of Alzheimer’s disease. Aβ peptide production results from the specific proteolytic processing of the amyloid precursor protein (APP)....

["Biophysics","Biotechnology","Cell Biology","Molecular Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2804v1
15 downloads
93 views

Background. Fibroblast growth factors (FGFs) and their receptors (FGFRs) are involved in the development and function of multiple organs and organ systems, including the central nervous system (CNS). FGF signaling via FGFR1, one of the three FGFRs expressed in...

["Cell Biology","Developmental Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2729v1
71 downloads
383 views

Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, that is, analyzing...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2725v1
103 downloads
252 views

A major goal of systems neuroscience is to understand how the brain represents information, and how those representations are used to drive behavior. Even though genetic model organisms like Drosophila grant unprecedented experimental access to the nervous system...

["Animal Behavior","Computational Biology","Neuroscience"]
doi:10.7287/peerj.preprints.2720v1
31 downloads
174 views

Background. Bax Inhibitor-1 (BI-1), an integral transmembrane protein, acts as a suppressor of Bax-induced apoptosis through regulation of endoplasmic reticulum (ER) stress-induced cell death. The gene is highly conserved being found in a diverse range of organisms...

["Cell Biology","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.2548v1
53 downloads
170 views

Background. Firefighting requires tremendous cognitive demands including assessing emergency scenes, executing critical decisions, and situational awareness of their surroundings. The aim of this study was to determine the effects of differing rates of increasing...

["Neuroscience","Cognitive Disorders","Kinesiology"]
doi:10.7287/peerj.preprints.2524v1
27 downloads
162 views

Major risk factors for neurodegenerative diseases share brain hypometabolism as one common outcome. In turn, many neurodegenerative pathologies result in brain hypometabolism; both epilepsy and Alzheimer's disease are characterised by disruptions in glucose metabolism....

["Neuroscience","Metabolic Sciences"]
doi:10.7287/peerj.preprints.2521v1
41 downloads
144 views

The purpose of the study was to investigate the characteristics of the attentional network in college table tennis athletes. A total of 65 college students categorized as table tennis athlete group or non-athlete group participated in the study. All participants...

["Neuroscience","Kinesiology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.2508v1
131 downloads
317 views

The main function of brains is to generate adaptive behavior. Far from being the stereotypical, robot-like insect, the fruit fly Drosophila exhibits astounding flexibility and chooses different courses of actions even under identical external circumstances. Due...

["Animal Behavior","Genetics","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.2491v1
71 downloads
192 views

As such, video games are enjoyed most when the level and speed of the game match the players’ skills. An optimal balance between challenges and skills triggers the subjective experience of “flow”, a focused motivation leading to a feeling of spontaneous joy. Here...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.2482v1
87 downloads
225 views

Increasingly complex data sets are needed to fully understand the complexity in behavior. Credit card sized single-board computers with multi-core CPUs are an attractive platform for designing devices capable of collecting multi-dimensional behavioral data. To...

["Animal Behavior","Bioengineering","Neuroscience"]
doi:10.7287/peerj.preprints.2435v1
52 downloads
328 views

The successful navigation of social interactions depends on a range of cognitive faculties – including the ability to achieve joint attention with others to share information and experiences. We investigated the influence that intention monitoring processes have...

["Neuroscience","Cognitive Disorders","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.2410v1
355 downloads
815 views

The ability to control the activity of specific neurons in freely behaving animals provides an effective way to probe the contributions of neural circuits to behavior. Wide interest in studying principles of neural circuit function using the fruit fly Drosophila...

["Animal Behavior","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.2354v2
37 downloads
147 views

As space flight becomes more accessible in the future, humans will be exposed to gravity conditions other than our 1G environment on Earth. Changes in physiology and anatomy in altered gravity conditions have long been observed, especially the loss of muscle mass...

["Developmental Biology","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.2363v1
What is a PeerJ Preprint?

A PeerJ Preprint is a draft of an article, abstract, or poster that has not yet been peer-reviewed for formal publication. Submit a draft, incomplete, or final version of your work for free.

Submissions today can be approved by Editorial Staff and online in 24 hours.

Establish precedent. Solicit feedback. Publish updates.

Top subject areas - Preprints

Top subject areas - People

View all subject areas