Preprints (not yet peer-reviewed)

Animals sense an enormous number of cues in their environments, and, over time, can form memories and associations to some of these. The nervous system remarkably maintains the specificity of memory to each of the cues. Here we asked whether the nematode Caenorhabditis...

["Animal Behavior","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.26451v1

Parkinson’s disease is a widespread condition caused by degeneration of dopamine neurons in the midbrain. A number of proteins are known to be important to signalling mechanisms present in the midbrain during natural dopamine neuron development, and may be utilised...

["Bioinformatics","Developmental Biology","Neuroscience"]
doi:10.7287/peerj.preprints.26443v2
103 downloads
250 views

In a recent paper, Joseph and colleagues (Joseph et al., 2017) have characterized the selective sucrose receptor IR60b in Drosophila, and proposed that it serves to limit sucrose consumption, and thus to prevent overfeeding. Here, we propose an alternative hypothesis...

["Animal Behavior","Neuroscience"]
doi:10.7287/peerj.preprints.3511v1
188 downloads
283 views

We propose a new hypothesis about the physical-chemical mechanisms of nerve conduction in myelinated nerves, tending to bridge the theoretical gap existing to date between the basic neuronal activity and its adaptation to myelination. All the considerations imply...

["Biochemistry","Neuroscience","Neurology"]
doi:10.7287/peerj.preprints.3409v1
31 downloads
101 views

Auditory steady-state responses (ASSRs) are sustained potentials used to assess the physiological integrity of the auditory pathway and objectively estimate hearing thresholds. ASSRs are typically analyzed using statistical procedures in order to remove the subjective...

["Neuroscience","Otorhinolaryngology"]
doi:10.7287/peerj.preprints.3399v1
99 downloads
259 views

Language and music are peculiar human behaviors. We spend a large portion of our lives speaking, reading, processing speech, performing music and listening to tunes. At the same time, we still know very little as to why and how these structured behaviors emerged...

["Anthropology","Evolutionary Studies","Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.3366v1
2,473 downloads
338 views

Underpowered experiments have three problems: the probability of a false positive result is higher, true effects are harder to detect, and the true effects that are detected tend to have inflated effect sizes. Many biology experiments are underpowered and recent...

["Animal Behavior","Neuroscience","Drugs and Devices","Ethical Issues","Statistics"]
doi:10.7287/peerj.preprints.3363v1
66 downloads
401 views

Background. It has been suggested that failure to establish cerebral lateralisation may be related to developmental language disorder (DLD). There has been weak support for any link with handedness, but more consistent reports of associations with functional brain...

["Neuroscience","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.3352v1
28 downloads
192 views

When two identical objects travel toward each other, overlap completely, and continue on toward opposite ends of a space, observers perceive them as streaming through or bouncing off each other (stream/bounce perception). In this phenomenon, proportion of perceiving...

["Neuroscience","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.3305v1
54 downloads
416 views

Increasing empirical research shows a deep connection between timing processes and neural processing of social information. An integrative theoretical framework for prospective studies in humans was recently proposed, linking timing to sociality. A similar framework...

["Animal Behavior","Evolutionary Studies","Neuroscience","Zoology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.3275v1
21 downloads
301 views

Background: Drugs for dementia have been available in England from 1997. Since their launch, there have been several changes to national guidelines and initiatives that may have influenced prescribing. These include changes in National Institute for health and...

["Neuroscience","Epidemiology","Pharmacology","Statistics"]
doi:10.7287/peerj.preprints.3238v1
789 downloads
531 views

One of the great mysteries of the brain, which has puzzled all-time students of brain form and function is the contralateral organization of the forebrain, and the crossings of its major afferent and efferent connections. As a novel explanation, two recent studies...

["Developmental Biology","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.432v3
238 downloads
395 views

Landscapes of Fear (LOF), the spatially explicit distribution of perceived predation risk as seen by a population, is increasingly cited in ecological literature and has become a frequently used “buzz-word”. With the increase in popularity, it became necessary...

["Animal Behavior","Conservation Biology","Ecology","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.2840v4
36 downloads
216 views

Background. Parkinson’s disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. The etiology of PD remains uncertain—some cases are due to selected genes associated with familial heredity, others are due to environmental exposure...

["Microbiology","Neuroscience","Infectious Diseases"]
doi:10.7287/peerj.preprints.3152v1
71 downloads
115 views

It is well documented that coordination of feeding behavior in anuran amphibians requires precise coordination of the jaw levators and depressors with the timing of the protraction of the tongue. (for review, see Nishikawa, 2000). However, the neuronal mechanism...

["Developmental Biology","Neuroscience"]
doi:10.7287/peerj.preprints.3131v1
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