Preprints (not yet peer-reviewed)

256 downloads
630 views

The viability of DNA metabarcoding for assessment of freshwater macrozoobenthos has been demonstrated over the past years. It matured to a stage where it can be applied to monitoring at a large scale, keeping pace with increased high throughput sequencing (HTS)...

["Molecular Biology","Freshwater Biology"]
doi:10.7287/peerj.preprints.3456v2
19 downloads
63 views

Swine are economically important food animals, but highly contagious enteric viruses can affect entire swine herds and contribute significantly to piglet morbidity and mortality. The most frequent viruses associated with pig gastroenteritis have been reported as...

["Molecular Biology","Veterinary Medicine","Virology"]
doi:10.7287/peerj.preprints.3515v1
21 downloads
96 views

Apis cerana cerana relies on the sensitive olfactory system to perform the foraging activities in the surrounding environment. Olfactory receptors (ORs) are a primary requirement for odorant recognition and coding. However, the molecular recognition of volatile...

["Cell Biology","Entomology","Molecular Biology"]
doi:10.7287/peerj.preprints.3513v1
7 downloads
57 views

Background. Astragalus was a well-known traditional herbal medicine, widely used in human s , livestock and poultry in China and E ast Asia. Fermentation could improve health-promoting biological substance by probiotics. Methods. We investigated Astragalus that...

["Agricultural Science","Biotechnology","Molecular Biology"]
doi:10.7287/peerj.preprints.3512v1
38 downloads
99 views

Background. Pluripotent stem cells (PSCs) offer immense potential as a source for regenerative therapies. The teratoma assay is widely used in the field of stem cells and regenerative medicine, but the cell composition of teratoma is still elusive. Methods. We...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3479v1
32 downloads
90 views

Background. Real-time quantitative PCR (qPCR) is a broadly used technique in the biomedical research. Currently, few different analysis models are used to determine the quality of data and to quantify the mRNA level across the experimental conditions. Methods....

["Bioinformatics","Cell Biology","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3477v1
198 downloads
430 views

Organisms of all kinds leave genetic traces in their environments, and in recent years, sequencing this environmental DNA (eDNA) has become a tractable means of surveying many species using water, air, or soil samples. The technique is beginning to become a core...

["Biodiversity","Ecology","Marine Biology","Molecular Biology","Biological Oceanography"]
doi:10.7287/peerj.preprints.3436v1
40 downloads
125 views

Arbutin (p-hydroxyphenyl-β-D-glucopyranoside), a well-known tyrosinase inhibitor, has been widely used as a cosmetic whitening agent. Although its natural role is to scavenge free radicals within cells, it has also exhibited useful activities for the treatment...

["Animal Behavior","Biochemistry","Molecular Biology"]
doi:10.7287/peerj.preprints.3405v1
35 downloads
142 views

Background: Haemophilus parasuis is a common porcine respiratory disease that causes high rates of morbidity and mortality in farmed swine. We performed a molecular characterization of antimicrobial resistance genes harbored by H. parasuis from pig farms in China....

["Microbiology","Molecular Biology","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.3386v1
35 downloads
153 views

Specific regulation and activation of focal adhesion kinase (FAK) are thought to be important for focal adhesion formation, and activation of Rho-kinase has been suggested to play a role in determining the effects of FAK on the formation of stress fibers and focal...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3297v1
62 downloads
155 views

Corals rely on a symbiosis with dinoflagellate algae (Symbiodinium spp.) to thrive in nutrient poor tropical oceans. However, the coral-algal symbiosis can break down during bleaching events, potentially leading to coral death. While genome-wide expression studies...

["Genetics","Marine Biology","Molecular Biology","Zoology"]
doi:10.7287/peerj.preprints.3283v1
240 downloads
809 views

DNA metabarcoding provides species composition data for entire communities, yet information on intraspecific diversity is usually lost during data analysis. The capacity to infer intraspecific genetic diversity within whole communities would, however, represent...

["Biogeography","Bioinformatics","Molecular Biology","Freshwater Biology"]
doi:10.7287/peerj.preprints.3269v1
104 downloads
222 views

Although most reef-building corals live near the upper threshold of their thermotolerance, some scleractinians are resilient to temperature increases. For instance, Pocillopora acuta specimens from an upwelling habitat in Southern Taiwan survived a 9-month experimental...

["Cell Biology","Environmental Sciences","Marine Biology","Molecular Biology","Climate Change Biology"]
doi:10.7287/peerj.preprints.3252v1
16 downloads
102 views

Microfluidic cell culture chambers have enabled the isolation, culture and growth of various species of microorganisms and human cells. However, based on elastomers such as poly(dimethyl siloxane) (PDMS), these culture devices are not readily amenable to imaging...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3245v1
59 downloads
297 views

The gastro-intestinal (GI) microbiota of abalone contains a highly complex bacterial assemblage playing an essential role in the overall health of these gastropods. The gut bacterial communities characterized so far reveal considerable interspecific variability,...

["Bioinformatics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3233v1
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