Preprints (not yet peer-reviewed)

48 downloads
106 views

Setting Seven public tuberculosis (TB) units in Kampala, Uganda, where Uganda’s national TB program recently introduced household contact investigation, as recommended by 2012 guidelines from WHO. Objective To apply a cascade analysis to implementation of household...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.3313v1
25 downloads
190 views

Bacterial surfaces are complex, built of from membranes, peptide-glycans and, importantly, proteins. The proteins play crucial roles as the key regulator of how the bacterium interacts with its environment. A full catalog of the motifs in coiled-coil proteins and...

["Bioinformatics","Infectious Diseases","Data Science"]
doi:10.7287/peerj.preprints.3118v2
19 downloads
103 views

Background. Antimicrobial drugs in veterinary medical practice are primarily prescribed for the purposes of maintaining or improving health and increasing productivity. However, their value is being eroded by antimicrobial resistance (AMR). Indiscriminate use of...

["Veterinary Medicine","Epidemiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.3253v1
27 downloads
179 views

Background. Parkinson’s disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. The etiology of PD remains uncertain—some cases are due to selected genes associated with familial heredity, others are due to environmental exposure...

["Microbiology","Neuroscience","Infectious Diseases"]
doi:10.7287/peerj.preprints.3152v1
197 downloads
2,208 views

Objective: In this study the main aspects of influenza transmission via fine and ultrafine bioaerosols were considered. Here, we aimed to estimate the impact of the different environment conditions on the deposition rate of the infectious bioaerosols in the respiratory...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.2237v5
36 downloads
630 views

We have originally shown for the first time the two different climatic patterns of seasonality of influenza and common colds have an only one common “link”. It is the effect of supersaturation and condensational growth in the upper airways which occurs under specific...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.2859v2
15 downloads
128 views

According to our clinical experience, cellulitis is common in summer; however, very few studies have mentioned this trend. Using Google Trends, we analyzed the monthly data of Google searches for ‘cellulitis’ from 31 countries on six continents. Seasonality explained...

["Dermatology","Epidemiology","Global Health","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.3124v1
31 downloads
77 views

Bacterial efflux pumps have emerged as antibiotic resistance determinants and confers multidrug resistance to a broad range of antimicrobials as well as non-antibiotic substances by potentially extruding them out. These are also associated with the virulence and...

["Microbiology","Global Health","Infectious Diseases"]
doi:10.7287/peerj.preprints.3091v1
18 downloads
219 views

Human papillomavirus type 16 (HPV16) is the most carcinogenic HPV, causing >50% of cervical cancers. Its unique oncogenicity is unsolved, e.g., the second most carcinogenic type (HPV18, causing ~16% of cancers) is relatively distantly related to HPV16. Mirabello...

["Bioinformatics","Evolutionary Studies","Infectious Diseases","Oncology","Women's Health"]
doi:10.7287/peerj.preprints.3070v1
20 downloads
125 views

Chlamydia trachomatis is usally isolated only from humans and is often infected together with other sexually transmitted diseases(STD). C. trachomatis is a serious disease which infects 500 million people per year globally and causes blindness in 7 to 9 million...

["Biochemistry","Microbiology","Molecular Biology","Immunology","Infectious Diseases"]
doi:10.7287/peerj.preprints.3056v1
38 downloads
261 views

Households are an important location for the transmission of communicable diseases. Social contact between household members is typically more frequent, of greater intensity, and is more likely to involve people of different age groups than contact occurring in...

["Anthropology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.3022v1
82 downloads
164 views

Background. The Ebola Virus Disease (EVD) is a highly infectious disease that has claimed over 25,000 cases in the past 50 years. While many past outbreaks of EVD resulted in relatively few incidents, the 2014 outbreak in West Africa was the most deadly occurrence...

["Virology","Epidemiology","Infectious Diseases","Statistics"]
doi:10.7287/peerj.preprints.3021v1
56 downloads
178 views

A scientific theory or hypothesis is presented, in which mineral particles may play a pivotal role in the prion disease transmissible spongiform encephalopathy (TSE), and possibly also in other protein-misfolding diseases. Montmorillonite clay (Mte) and other minerals...

["Cell Biology","Molecular Biology","Infectious Diseases","Neurology"]
doi:10.7287/peerj.preprints.2982v1
31 downloads
194 views

Antibiotic-resistant bacteria complicate many infections and can be difficult to eradicate from hospitals. The population dynamics and ecology of these organisms in the hospital setting, however, is not well understood. Here, we report extensive strain-based antagonistic...

["Ecology","Microbiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2973v1
85 downloads
371 views

The Ebola virus, a negative-sense single-stranded RNA virus, causes severe viral hemorrhagic fever and is highly lethal. Histopathology and immunopathologic study of Ebola virus have revealed that histopathologic changes in skin tissue were mainly various degrees...

["Bioinformatics","Microbiology","Infectious Diseases","Medical Genetics"]
doi:10.7287/peerj.preprints.2959v1
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