Preprints (not yet peer-reviewed)

129 downloads
1,040 views

As the generation and use of genomic datasets is becoming increasingly common in all areas of biology, the need for resources to collate, analyse and present data from one or more genome projects is becoming more pressing. The Ensembl platform is a powerful tool...

["Bioinformatics","Genomics"]
doi:10.7287/peerj.preprints.2401v2
24 downloads
92 views

Platycladus orientalis in China has a lifespan of one to several thousands of years. The long lifespans of trees have attracted interest in aging at the molecular level. There is little information on how the global process is controlled. In this study, the MDA...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2866v1
40 downloads
227 views

Metatranscriptomics and metaproteomics make it possible to measure gene expression in microbial communities. So far these approaches were mostly used to get a general overview of the dominant metabolism and physiologies of community members. Recently, environmental...

["Bioinformatics","Ecology","Environmental Sciences","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2846v1
16 downloads
112 views

Microorganism is an important part of ecosystems; it is very sensitive to environmental change. In order to study the effects of sound on organisms, it’s meaningful to study mechanism of microbial exposure to sound. In our previous experiments, the effects of different...

["Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2821v1
44 downloads
124 views

Aerobic anoxygenic phototrophic bacteria (AAPB) containing bacteriochlorophyll a (BChl a) are photoheterotrophic prokaryotes that are a widely distributed functional bacterial group due to their obligately aerobic and facultative photoheterotrophic abilities. Here,...

["Ecology","Environmental Sciences","Genomics","Marine Biology","Microbiology"]
doi:10.7287/peerj.preprints.2820v1
9 downloads
94 views

Basic idea of science is reproducibility of phenomena and experiments. Reproducibility of data analyses and reports is becoming more and more important. It requires structured organization of data, augmented with enought metadata for future re-use of data. Our...

["Bioinformatics","Genomics","Plant Science","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2791v1
728 downloads
563 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6
24 downloads
111 views

American trypanosomiasis is a chronic and endemic disease, which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions....

["Biochemistry","Genomics","Molecular Biology","Parasitology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2782v1
34 downloads
252 views

Introduction 2nd generation sequencing or better known as next-generation sequencing (NGS) represents a cutting-edge technology in life sciences and current foundation for unravelling nucleotide sequences. Since advent of first platforms in 2005 the number of different...

["Bioinformatics","Biotechnology","Genomics","Molecular Biology"]
doi:10.7287/peerj.preprints.2771v1
104 downloads
260 views

Background RNA sequencing (RNA-Seq) is a powerful technique for transcriptome profiling of the organisms that uses the capabilities of next-generation sequencing (NGS) technologies. Recent advances in NGS let to measure the expression levels of tens to thousands...

["Bioinformatics","Genomics","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.2761v1
63 downloads
109 views

The human male specific Y-chromosome passes from father to son essentially unchanged, but occasionally a random change, known as a mutation, occurs. These mutations, also called markers, serve as beacons and can be mapped. When geneticists identify a mutation in...

["Anthropology","Genetics","Genomics"]
doi:10.7287/peerj.preprints.2755v1
60 downloads
221 views

Introduction Next Generation Sequencing (NGS) platforms have radically changed the field of genomics and are routinely applied to a variety of functional genomics problems. Although NGS has markedly accelerated multiple areas of genomics research it is a massively...

["Bioinformatics","Genomics","Molecular Biology","Computational Science"]
doi:10.7287/peerj.preprints.2752v1
34 downloads
355 views

Background. Opsin proteins are seven transmembrane receptor proteins which detect light. Opsins can be classified into two types and share little sequence identity: type 1, typically found in bacteria, and type 2, primarily characterized in metazoa. The type 2...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Mycology"]
doi:10.7287/peerj.preprints.2397v2
17 downloads
75 views

Structure informs function, and this may be the evolutionary reason why alternative splicing, which is capable of generating different variants of the same protein, arise. But, given the energetic cost of generating different splice variants for testing their capability...

["Biochemistry","Bioinformatics","Genomics","Molecular Biology","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.2717v1
41 downloads
168 views

Background: Geminivirus (family Geminiviridae) is a prevalent plant virus that imperils agriculture globally, causing serious damage to the livelihood of farmers, particularly in developing countries. The virus evolves rapidly, attributing to its single-stranded...

["Agricultural Science","Bioinformatics","Genomics","Virology"]
doi:10.7287/peerj.preprints.2705v1
What is a PeerJ Preprint?

A PeerJ Preprint is a draft of an article, abstract, or poster that has not yet been peer-reviewed for formal publication. Submit a draft, incomplete, or final version of your work for free.

Submissions today can be approved by Editorial Staff and online in 24 hours.

Establish precedent. Solicit feedback. Publish updates.

Top subject areas - Preprints

Top subject areas - People

View all subject areas