Preprints (not yet peer-reviewed)

2 downloads
55 views

Structure informs function, and this may be the evolutionary reason why alternative splicing, which is capable of generating different variants of the same protein, arise. But, given the energetic cost of generating different splice variants for testing their capability...

["Biochemistry","Bioinformatics","Genomics","Molecular Biology","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.2717v1
14 downloads
92 views

Background: Geminivirus (family Geminiviridae) is a prevalent plant virus that imperils agriculture globally, causing serious damage to the livelihood of farmers, particularly in developing countries. The virus evolves rapidly, attributing to its single-stranded...

["Agricultural Science","Bioinformatics","Genomics","Virology"]
doi:10.7287/peerj.preprints.2705v1
43 downloads
306 views

A key step in the transformation of raw sequencing reads into biological insights is the trimming of adapter sequences and low-quality bases. Read trimming has been shown to increase the quality and reliability while decreasing the computational requirements of...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.2452v3
27 downloads
218 views

Cyanobacteria are major contributors to global biogeochemical cycles. The genetic diversity among Cyanobacteria enables them to thrive across many habitats. However, the taxonomy of Cyanobacteria remains unstable because of an inadequate taxonomic classification...

["Bioinformatics","Ecology","Genomics","Microbiology","Taxonomy"]
doi:10.7287/peerj.preprints.2676v1
39 downloads
602 views

Background Transposable element (TE) polymorphisms are important components of population genetic variation. The functional impacts of TEs in gene regulation and generating genetic diversity have been observed in multiple species, but the frequency and magnitude...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2447v2
28 downloads
331 views

The genetic structure of bacterial populations can be related to geographical locations of isolation. In some species, there is a strong correlation between geographical distances and genetic distances, which can be caused by different evolutionary mechanisms....

["Biogeography","Bioinformatics","Genomics","Microbiology","Epidemiology"]
doi:10.7287/peerj.preprints.2638v1
32 downloads
109 views

Acidithiobacillus ferrooxidans ( A. ferrooxidans ) is a gram-negative, extremely acidophilic, mesophilic, chemolithotrophic bacterium and the most well-studied acidophilic organism which is usually found in acid environments such as acid mine drainage. The draft...

["Bioinformatics","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2620v1
119 downloads
384 views

The global deep subsurface biosphere is thought to be one of the largest reservoirs for microbial life on our planet. This study takes advantage of new sampling technologies and couples them with improvements to DNA sequencing and associated informatics tools to...

["Bioinformatics","Environmental Sciences","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2613v1
36 downloads
136 views

Background. Resurrection plants constitute a unique cadre within angiosperms. Boea clarkeana Hemsl. (Boea, Gesneriaceae) is a desiccation-tolerant dicotyledonous herb that is endemic to China. Although research on angiosperms with DT could be instructive for crops,...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2603v1
97 downloads
284 views

It is generally accepted that diverse, poorly characterized microorganisms reside deep within Earth’s crust. One such lineage of deep subsurface-dwelling Bacteria is an uncultivated member of the Firmicutes phylum that can dominate molecular surveys from both marine...

["Ecology","Genomics","Microbiology"]
doi:10.7287/peerj.preprints.2592v1
87 downloads
117 views

Presentations in session one of the Society of Environmental Toxicology and Chemistry (SETAC) North America Focused Topic Meeting: Endocrine Disruption (February 4 – 6, 2014) described where the science and the regulations have arrived and identified the key challenges...

["Ecology","Environmental Sciences","Genomics","Toxicology","Histology"]
doi:10.7287/peerj.preprints.2583v1
36 downloads
74 views

This special series of six papers (this introductory paper and 5 other papers) is about the Focused Topic Meeting on Endocrine Disruption Chemical Testing; Risk Assessment Approaches and Implications (4 – 6 February, 2014, Raleigh, North Carolina). The workshop...

["Ecology","Environmental Sciences","Genomics","Toxicology"]
doi:10.7287/peerj.preprints.2578v1
74 downloads
729 views

OncoRank adopts a method for finding recurrent miRNA-target interactions to find genes with consistent relationships to patient survival across cancers. Genes are first ranked in each cancer by their Cox coefficients, and these ranks are then combined by applying...

["Bioinformatics","Genomics","Oncology"]
doi:10.7287/peerj.preprints.2574v1
49 downloads
252 views

From early 2012, a novel clone of vancomycin resistant Enterococcus faecium (assigned the multi locus sequence type ST796) was simultaneously isolated from geographically separate hospitals in south eastern Australia and New Zealand. Here we describe the complete...

["Evolutionary Studies","Genomics","Microbiology","Epidemiology","Infectious Diseases"]
doi:10.7287/peerj.preprints.2562v1
101 downloads
88 views

We report the development and characterization of 13 novel microsatellite loci for the Caribbean queen conch, Lobatus gigas, an ecologically and commercially important marine gastropod. Paired-end sequencing was carried out on genomic DNA from a single queen conch...

["Bioengineering","Bioinformatics","Conservation Biology","Genetics","Genomics"]
doi:10.7287/peerj.preprints.2559v1
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