Preprints (not yet peer-reviewed)

8 downloads
52 views

Research in Arabidopsis and other model species has uncovered mechanisms regulating important biological processes in plants. With the advent of high quality functional genomic resources in wheat it is now possible to use this knowledge for crop improvement directly...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26877v1
25 downloads
94 views

Strawberry (Fragaria × ananassa) is an ideal plant for fruit development and ripening research due to the rapid substantial changes in fruit color, aroma, taste and softening. To gain deeper insights into the genes that play a central regulatory role in strawberry...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26870v1
224 downloads
572 views

Many pressing medical challenges -- such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers -- have long been hindered by limitations in our ability to quantify proteins in single cells. Mass-spectrometry (MS) is poised...

["Bioengineering","Biotechnology","Cell Biology","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.26821v1
161 downloads
342 views

Background. Cytoplasmic male sterility (CMS) is a common phenotype in higher plants, which often is associated with rearrangements in mitochondrial DNA (mtDNA), and is widely used to produce hybrid seeds in a variety of valuable crop species. The CMS phenomenon...

["Agricultural Science","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26438v2
198 downloads
460 views

Horizontal gene transfer has had major impacts on the biology of a wide range of organisms from antibiotic resistance in bacteria to adaptations to herbivory in arthropods. A growing body of literature shows that horizontal gene transfer (HGT) between non-animals...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3462v2
149 downloads
265 views

The Centre for Environmental Genomics Applications (CEGA) is a new research facility in Eastern Canada dedicated to the development of environmental DNA (eDNA) approaches to biomonitoring and biodiversity assessment with a focus on marine environments. Genomics...

["Biodiversity","Genomics"]
doi:10.7287/peerj.preprints.26814v1
32 downloads
129 views

Wheat streak mosaic virus (WSMV) causes streak mosaic disease in wheat (Triticum aestivum L.) and has been an important constraint limiting wheat production in many regions around the world. Wsm2 is the only resistance gene discovered in wheat genome and has been...

["Agricultural Science","Bioinformatics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26802v1
1,197 downloads
3,745 views

Almost a decade ago, the sequencing of ancient DNA from archaic humans - Neanderthals and Denisovans - revealed that modern and archaic humans interbred at least twice during the Pleistocene. The field of human paleogenomics has now turned its attention towards...

["Anthropology","Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.26782v2
306 downloads
763 views

The study of biodiversity within the spatiotemporal continuum of evolution, e.g., studying local communities, population dynamics, or phylogenetic diversity, has been important to properly identify and describe the current biodiversity crisis. However, it has become...

["Biodiversity","Entomology","Evolutionary Studies","Genomics","Zoology"]
doi:10.7287/peerj.preprints.26661v2
72 downloads
248 views

Background. Comparative genomics between closely related bacterial strains aids to distinguish important features like pathogenesis, antibiotic resistance, and phylogenetic structure. Streptococcus is relevant because public health and food safety and it are well-represented...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26665v1
63 downloads
191 views

Multilocus sequence typing (MLST) is a standard tool in population genetics and bacterial epidemiology that assesses the genetic variation present in a reduced number of housekeeping genes (typically seven) along the genome. This methodology assigns arbitrary integer...

["Bioinformatics","Ecology","Genomics","Microbiology","Population Biology"]
doi:10.7287/peerj.preprints.26630v2
291 downloads
501 views

Normalization is the first critical step in microbiome sequencing data analysis used to account for variable library sizes. Current RNA-Seq based normalization methods that have been adapted for microbiome data fail to consider the unique characteristics of microbiome...

["Bioinformatics","Genomics","Statistics"]
doi:10.7287/peerj.preprints.3417v3
31 downloads
77 views

The glutathione-S-transferase (GST) family of proteins is ancient and versatile, and plays an important role in combating exogenous pathogens, endogenous toxicants, and various abiotic stresses. Although the GST family has been studied in many crops, few studies...

["Agricultural Science","Bioinformatics","Genomics","Molecular Biology"]
doi:10.7287/peerj.preprints.26629v1
38 downloads
80 views

There are substantial subtelomeric interstitial telomeric sequence (ITS) in the human genome, however the origin of these sequences is not well understood. We investigate the possibility that these ITS have arisen via a process of chromosome end extension to the...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.26624v1
115 downloads
278 views

Dot plots are widely used to quickly compare sequence sets. They provide a synthetic similarity overview, highlighting repetitions, breaks and inversions. Different tools have been developed to easily generated genomic alignment dot plots, but they are often limited...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.26567v1
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