Preprints (not yet peer-reviewed)

177 downloads
605 views

Evolutionary biology has entered an era of unprecedented amounts of DNA sequence data, as new sequencing platforms such as Massive Parallel Sequencing (MPS) can generate billions of nucleotides within less than a day. The current bottleneck is how to efficiently...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.26477v3
90 downloads
199 views

The process of domestication presents a tractable system for following evolutionary change, as selective pressures shift, resulting in adaptation to the new ecological niche of cultivation. Perhaps the most detailed understanding of this process comes from Zea...

["Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.26502v1
44 downloads
206 views

The presence of topographic features, such as mid-ocean ridges, can divide the abyss into basins, which can be interconnected through gaps and potentially affect species distribution and dispersal. Holding endemic and widespread species, nematodes represent ideal...

["Biodiversity","Ecology","Genetics","Marine Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.26492v1
24 downloads
82 views

Proteins that modify the activity of transcription factor (TF), often called modulators, play a vital role in gene transcriptional regulation. Alternative splicing is a critical step of gene processing and it can modulate gene function by adding or removing certain...

["Bioengineering","Bioinformatics","Biotechnology","Genetics","Computational Science"]
doi:10.7287/peerj.preprints.26482v1
100 downloads
149 views

We used Massively Parallel High-Throughput Sequencing to obtain genetic data from a 145-year old holotype specimen of the flying lizard, Draco cristatellus. Obtaining genetic data from this holotype was necessary to resolve an otherwise intractable taxonomic problem...

["Genetics","Genomics","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.26466v1
45 downloads
113 views

Animals sense an enormous number of cues in their environments, and, over time, can form memories and associations to some of these. The nervous system remarkably maintains the specificity of memory to each of the cues. Here we asked whether the nematode Caenorhabditis...

["Animal Behavior","Genetics","Neuroscience"]
doi:10.7287/peerj.preprints.26451v1
112 downloads
192 views

Background. Cytoplasmic male sterility (CMS) is a common phenotype in higher plants, which often is associated with rearrangements in mitochondrial DNA (mtDNA), and is widely used to produce hybrid seeds in a variety of valuable crop species. The CMS phenomenon...

["Agricultural Science","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26438v1
78 downloads
366 views

Dopamine receptors are integral membrane proteins whose endogenous ligand is dopamine. They play a fundamental role in the central nervous system and dysfunction of dopaminergic neurotransmission is responsible for the generation of a variety of neuropsychiatric...

["Evolutionary Studies","Genetics","Genomics"]
doi:10.7287/peerj.preprints.4043v1
116 downloads
298 views

Background.The insect cuticle covers the whole body and all appendages and has bi-directionnal selective permeability: it protects against environmental stress and pathogen infection and also helps to reduce water loss. The adult cuticle is often associated with...

["Ecology","Entomology","Genetics"]
doi:10.7287/peerj.preprints.3501v1
78 downloads
177 views

The native ranges and invasion histories of many marine species remain elusive due to a dynamic dispersal process via marine vessels. Molecular markers can aid in identification of native ranges and elucidation of the introduction and establishment process. The...

["Biodiversity","Biogeography","Evolutionary Studies","Genetics","Marine Biology"]
doi:10.7287/peerj.preprints.3497v1
37 downloads
109 views

Background. Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. The disease in horses has complex inheritance including both dominant and recessive patterns that are ill defined. This study...

["Genetics","Veterinary Medicine","Allergy and Clinical Immunology","Respiratory Medicine"]
doi:10.7287/peerj.preprints.3491v1
379 downloads
513 views

Generating heatmaps of genetic datasets is a 2D graphical visualization of data where the individual expression values contained in a matrix are represented as colors. Herein, we describe AFCMHeatMap a shiny web App that integrates quantitative interaction of genomics...

["Bioinformatics","Computational Biology","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.2961v2
123 downloads
259 views

Unknown sequences, or gaps, are largely present in most published genomes across public databases. Gap filling is an important finishing step in de novo genome assembly, especially in large genomes. The gap filling problem is nontrivial and while many computational...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3467v1
148 downloads
369 views

Information on the genetic control of the quality traits of soft wheat (Triticum aestivum L. em. Thell) is essential for breeding. Gluten strength is a measure of quality and has particular relevance to soft wheat as identity-preserved programs for strong-gluten...

["Agricultural Science","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.3466v1
52 downloads
173 views

Housekeeping genes are ubiquitously expressed and maintain basic cellular function across tissue/cell types conditions. The present study aimed to develop a set of pig housekeeping genes and compare characteristics of structure, evolution and function of housekeeping...

["Bioinformatics","Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.3450v1
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