Preprints (not yet peer-reviewed)

41 downloads
254 views

Purpose: This study was performed to investigate the expression pattern of Wnt inhibitory factor 1 (Wif1) during anorectal development in normal and anorectal malformation (ARM) embryos and the possible role of Wif1 in the pathogenesis of ARM. Methods: ARM was...

["Developmental Biology","Gastroenterology and Hepatology","Pediatrics"]
doi:10.7287/peerj.preprints.3459v1
118 downloads
195 views

Background: Liver pathology in cats represents a frequent clinical condition occurring in animals of any age. Dietary supplementation with hepatoprotective and antioxidant products could represent a beneficial strategy to prevent and treat these disorders. We evaluated...

["Veterinary Medicine","Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.3349v1
251 downloads
522 views

Prebiotics are selectively fermentable dietary compounds that result in changes in the composition and/or activity of the intestinal microbiota, thus conferring benefits upon host health. In veterinary medicine, commercially available products containing prebiotics...

["Bioinformatics","Microbiology","Veterinary Medicine","Gastroenterology and Hepatology","Nutrition"]
doi:10.7287/peerj.preprints.2814v1
177 downloads
515 views

The intestinal microbiota is associated with human health. The luminal microbiota (LM) and mucosa-associated microbiota (MAM) are distinct ecosystems with different metabolic and immunological functions. Several studies have examined the correlations between the...

["Genomics","Microbiology","Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.2526v1
81 downloads
305 views

Background. Preanalytic factors such as time and temperature can have significant effects on laboratory test results. For example, ammonium concentration will increase 31% in blood samples stored at room temperature for 30 minutes before centrifugation. To reduce...

["Biochemistry","Veterinary Medicine","Emergency and Critical Care","Gastroenterology and Hepatology","Hematology"]
doi:10.7287/peerj.preprints.2398v1
115 downloads
367 views

Objective: The aim of this study was to use the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines to evaluate the quality of reporting of recent gastric cancer animal experiments. Materials and Methods: A literature search of studies was performed...

["Veterinary Medicine","Gastroenterology and Hepatology","Oncology","Translational Medicine","Statistics"]
doi:10.7287/peerj.preprints.2049v1
122 downloads
359 views

The clinical utility of microbiome biomarkers depends on the reliable and reproducible nature of comparative results. Underappreciation of the variation associated with common demographic, health, and behavioral factors may confound associations of interest and...

["Microbiology","Gastroenterology and Hepatology","Public Health","Statistics"]
doi:10.7287/peerj.preprints.1512v1
74 downloads
267 views

Background. Epigenetic influences have been implicated in the development of autoimmunity. While such mechanisms have been linked to mouse models of intestinal inflammation, and to human inflammatory bowel disease (IBD), the involvement of epigenetic mechanisms...

["Molecular Biology","Gastroenterology and Hepatology","Immunology"]
doi:10.7287/peerj.preprints.1391v1
73 downloads
382 views

Background. High quality patient specific 3D liver models can be nowadays exported using computer liver segmentation algorithms. Specific 3D image editing tools can be used to manipulate the liver models and create virtual surgical cases. Objective. The aim of...

["Gastroenterology and Hepatology","Surgery and Surgical Specialties","Science and Medical Education"]
doi:10.7287/peerj.preprints.1090v1
102 downloads
331 views

Background. Severe obesity is a risk factor for lower participation in paid work, but whether employment increases and sick leave decreases after obesity surgery is not well documented. Methods. We assessed 224 Norwegian patients with severe obesity (mean age:...

["Epidemiology","Gastroenterology and Hepatology","Nursing","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.923v1
798 downloads
2,556 views

A previous study revealed loop formation of the colonoscope in the sigmoid colon in 79% of patients. Colonoscope looping in the sigmoid colon is considered to cause abdominal pain and intestinal perforation. We discovered a phenomenon whereby the rectosigmoid junction...

["Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.535v1
82 downloads
355 views

Background: Socioeconomic factors and insurance status have not been correlated with differential use of healthcare services in inflammatory bowel disease (IBD). Aim: To describe IBD-related expenditures based on insurance and household income with the use of inpatient,...

["Gastroenterology and Hepatology","Health Policy"]
doi:10.7287/peerj.preprints.476v1
138 downloads
482 views

Aim Helicobacter pylori (H. pylori) infection is exceptionally rare in population from the north-eastern region of Peninsular Malaysia. This provides us an opportunity to contemplate the future without H. pylori in acute non-variceal upper gastrointestinal (GI)...

["Epidemiology","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7287/peerj.preprints.180v1
333 downloads
2,770 views

We previously reported that the sigmoid-descending colon junction becomes linear and the colonoscope can be readily inserted into the descending colon in the left semiprone position. In addition, we encountered a situation whereby the sigmoid colon becomes more...

["Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.97v1
171 downloads
2,400 views

A previous study has shown barium is instilled in the left lateral position or the prone position. However, we previously reported that the colonoscope can be readily inserted into the descending colon in the left semiprone position. Indeed, when the colonoscope...

["Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.68v1
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