Preprints (not yet peer-reviewed)

35 downloads
78 views

Objective. In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7287/peerj.preprints.26518v1
16 downloads
42 views

Ribosomes are highly conserved given the importance of protein synthesis to cell survival. Although small differences in structure and functions exists in ribosomes from different species of bacteria, archaea and eukaryotes, the general structure and function remains...

["Biochemistry","Bioinformatics","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26511v1
22 downloads
51 views

Oligo-carrageenan (OC) kappa increases net photosynthesis, and basal and secondary metabolism enzyme activities in Eucalyptus globulus trees. Here, trees were sprayed on leaves with water (control) or with OC kappa 1 mg ml-1, once a week, four times in total, and...

["Agricultural Science","Biochemistry","Biotechnology","Cell Biology","Plant Science"]
doi:10.7287/peerj.preprints.26500v1
91 downloads
309 views

Background. Tissue engineering has been shown to exhibit great potential for the creation of biomaterials capable of developing into functional tissues. Cellular expansion and integration depends on the quality and surface-determinant factors of the scaffold, which...

["Bioengineering","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.3329v3
39 downloads
136 views

Apis cerana cerana relies on the sensitive olfactory system to perform the foraging activities in the surrounding environment. Olfactory receptors (ORs) are a primary requirement for odorant recognition and coding. However, the molecular recognition of volatile...

["Cell Biology","Entomology","Molecular Biology"]
doi:10.7287/peerj.preprints.3513v1
47 downloads
124 views

Background. Pluripotent stem cells (PSCs) offer immense potential as a source for regenerative therapies. The teratoma assay is widely used in the field of stem cells and regenerative medicine, but the cell composition of teratoma is still elusive. Methods. We...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3479v1
70 downloads
126 views

Background. Real-time quantitative PCR (qPCR) is a broadly used technique in the biomedical research. Currently, few different analysis models are used to determine the quality of data and to quantify the mRNA level across the experimental conditions. Methods....

["Bioinformatics","Cell Biology","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3477v1
43 downloads
146 views

Myogenesis is a complicated process, which is regulated by numerous regulators. MicroRNAs (miRNAs) are conserved non-coding RNAs of ~22 nucleotides, which regulate post-transcriptional gene expression in many physiological and pathophysiological processes. Recent...

["Agricultural Science","Biochemistry","Cell Biology"]
doi:10.7287/peerj.preprints.3454v1
42 downloads
171 views

Background. The c-mos proto-oncogene was one of the first proto-oncogenes to be cloned. Apart from its role in meiosis, many efforts have been made to illuminate the mechanisms by which c-mos acts as an oncogene. c-mos or its coding messenger RNA have been confirmed...

["Cell Biology","Oncology"]
doi:10.7287/peerj.preprints.3426v1
87 downloads
635 views

Background and purpose Oxidative stress is involved in normal and pathological functioning of skeletal muscle. Protection of myoblasts from oxidative stress may improve muscle contraction and delay aging. Here we studied the effect of R. coriaria sumac fruit extract...

["Cell Biology","Translational Medicine"]
doi:10.7287/peerj.preprints.3383v1
48 downloads
275 views

Previously, we revealed that several kampo medicines that are used for patients with excess and/or medium patterns [kakkonto (TJ-1), shosaikoto (TJ-9), hangeshashinto (TJ-14), and orento (TJ-120)] reduced prostaglandin (PG)E<2 levels using LPS-treated human gingival...

["Cell Biology","Dentistry","Pharmacology"]
doi:10.7287/peerj.preprints.3227v2
59 downloads
227 views

The spindle pole body (SPB) in fungi is the equivalent of the animal centrosome. A number of previous studies have identified many, if not all, components of the SPB. The SPB is the structural platform for microtubule nucleation and plays important roles, both...

["Cell Biology","Genetics"]
doi:10.7287/peerj.preprints.3377v1
117 downloads
254 views

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research. The ability to reprogrammed human somatic cells to a pluripotent embryonic stem cell-like state through...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7287/peerj.preprints.3374v1
29 downloads
125 views

While biochemistry evidently affects the growth rate of cells, many biochemists routinely ignore population variation, just like population geneticists usually ignore causal details of biochemistry that underpin a change in growth rate caused by a mutation. A true...

["Biochemistry","Cell Biology","Computational Biology","Oncology","Computational Science"]
doi:10.7287/peerj.preprints.3371v1
73 downloads
207 views

Many plant species exhibit heterophylly, displaying different leaves upon a single plant. The molecular mechanisms regulating this phenomenon, however, have remained elusive. In this study, the transcriptomes of submerged and floating leaves of an aquatic heterophyllous...

["Cell Biology","Developmental Biology","Evolutionary Studies","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.3336v1
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