Preprints (not yet peer-reviewed)

11 downloads
65 views

Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR) loops (H1,...

["Bioinformatics","Computational Biology"]
doi:10.7287/peerj.preprints.26996v1
70 downloads
184 views

Aggression is a serious behavioral disorder in domestic dogs that endangers both dogs and humans. The underlying causes of canine aggression are poorly resolved and require illumination to ensure effective therapy. Recent research links the compositional diversity...

["Animal Behavior","Bioinformatics","Microbiology"]
doi:10.7287/peerj.preprints.26990v1
22 downloads
109 views

Background. Intramuscular fat (IMF) is an important economic trait for pork quality and a complex quantitative trait regulated by multiple genes. The objective of this work was to investigate the novel transcriptional effects of a multigene pathways on IMF deposition...

["Agricultural Science","Bioinformatics","Molecular Biology"]
doi:10.7287/peerj.preprints.26976v1
34 downloads
196 views

Bacterial small non-coding RNAs (sRNAs) are involved in the control of several cellular processes. Hundreds of putative sRNAs have been identified in many bacterial species through RNA sequencing. The existence of putative sRNAs is usually validated by Northern...

["Bioinformatics","Microbiology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26974v1
126 downloads
411 views

The most abundant and ubiquitous microbes in the surface ocean use light as an energy source, capturing it via complex chlorophyll-based photosystems or simple retinal-based rhodopsins. Studies in various ocean regimes compared the abundance of these mechanisms,...

["Biodiversity","Bioinformatics","Ecology","Microbiology","Biological Oceanography"]
doi:10.7287/peerj.preprints.26950v1
69 downloads
224 views

Biodiversity information is made available through numerous databases that each have their own data models, web services, and data types. Combining data across databases leads to new insights, but is not easy because each database uses its own system of identifiers....

["Bioinformatics","Databases"]
doi:10.7287/peerj.preprints.26951v1
56 downloads
102 views

Flow cytometry (FCM) is a powerful analytical tool that is widely used worldwide, as it allows the depiction of the innate complexity of a vast range of biological systems in few seconds. It is a technique based on the spectroscopic properties of suspended particles...

["Bioinformatics","Computational Biology","Ecology","Ecosystem Science","Data Science"]
doi:10.7287/peerj.preprints.26934v1
156 downloads
330 views

Microbes are identified based on their distinguishing characteristics such as gene sequence or metabolic profile. Nucleic acid approaches such as 16S rRNA gene sequencing provide the gold standard method for microbial identification in the contemporary era. However,...

["Biochemistry","Bioinformatics","Biotechnology","Computational Biology","Microbiology"]
doi:10.7287/peerj.preprints.3524v2
139 downloads
463 views

Statistical books are an opportunity for accessing relatively deeper insights into statistics and software even outside the introductory classroom setting. There are however many resources available to the practitioner in addition to the traditional text model....

["Bioinformatics","Computer Education","Data Science","Programming Languages"]
doi:10.7287/peerj.preprints.26924v1
53 downloads
117 views

This paper discusses the difficulties experienced by bioinformaticians while working with extensive data generated from extended molecular dynamics simulations. For better experimental analysis, it often becomes crucial to conduct simulations up to extended periods...

["Bioinformatics","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.26920v1
149 downloads
482 views

Background. Comparative genomics between closely related bacterial strains can distinguish important features determining pathogenesis, antibiotic resistance, and phylogenetic structure. The Streptococcus genus is relevant to public health and food safety and it...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26665v2
179 downloads
889 views

Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly influence inferences of microbial...

["Biodiversity","Bioinformatics","Genomics","Microbiology","Veterinary Medicine"]
doi:10.7287/peerj.preprints.26912v1
397 downloads
1,167 views

Low-cost Illumina sequencing of clinically-important bacterial pathogens has generated thousands of publicly available genomic datasets. Analyzing these genomes and extracting relevant information for each pathogen and the associated clinical phenotypes requires...

["Bioinformatics","Genomics","Infectious Diseases","Public Health"]
doi:10.7287/peerj.preprints.26890v2
70 downloads
116 views

Xeno-miRNAs are microRNAs originating from exogenous species detected in host biofluids. A growing number of studies have suggested that many of these xeno-miRNAs may be involved in cross-species interactions by targeting host mRNAs. To date, hundreds of xeno-miRNAs...

["Bioinformatics","Computational Biology","Genetics","Genomics","Parasitology"]
doi:10.7287/peerj.preprints.26887v1
90 downloads
249 views

Since 2014 divers from Ocean Wise have been SCUBA diving in the Cambridge Bay, Nunavut area collecting data on fishes, invertebrates and marine plants at numerous sites. For each dive a file is created that catalogues the species found and a rough abundance of...

["Bioinformatics","Ecology","Marine Biology","Taxonomy"]
doi:10.7287/peerj.preprints.26850v2
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