Preprints (not yet peer-reviewed)

495 downloads
521 views

“Open access” has become a central theme of journal reform in academic publishing. In this article, I examine the relationship between open access publishing and an important infrastructural element of a modern research enterprise, scientific literature text mining,...

["Bioinformatics","Evidence Based Medicine","Health Policy","Translational Medicine","Science Policy"]
doi:10.7287/peerj.preprints.2566v2
2 downloads
34 views

Ribosomes are highly conserved macromolecular machines whose critical function is protein synthesis. However, existence of unique molecular mass of the same type of ribosomal protein for individual species in the same domain of life raises the interesting question...

["Biochemistry","Biodiversity","Bioinformatics","Biotechnology","Ecology"]
doi:10.7287/peerj.preprints.26878v1
148 downloads
309 views

The “reproducibility crisis” has been a highly visible source of scientific controversy and dispute. Here, I propose and review several avenues for identifying and prioritizing research studies for the purpose of targeted validation. Of the various proposals discussed,...

["Bioinformatics","Evidence Based Medicine","Health Policy","Translational Medicine","Science Policy"]
doi:10.7287/peerj.preprints.2830v2
64 downloads
142 views

The 16S rRNA gene amplicon sequencing is a widely used high-throughput method for the taxonomic inference in microbial communities. Many data analysis pipelines have been developed to enhance the accuracy in reflecting the real taxonomy, in order to better guide...

["Bioinformatics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26872v1
31 downloads
151 views

Strawberry (Fragaria × ananassa) is an ideal plant for fruit development and ripening research due to the rapid substantial changes in fruit color, aroma, taste and softening. To gain deeper insights into the genes that play a central regulatory role in strawberry...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.26870v1
32 downloads
113 views

With an unprecedented growth in the biomedical literature, keeping up to date with the new developments presents an immense challenge. Publications are often studied in isolation of the established literature, with interpretation being subjective and often introducing...

["Bioinformatics","Algorithms and Analysis of Algorithms","Data Mining and Machine Learning","Software Engineering","Visual Analytics"]
doi:10.7287/peerj.preprints.26869v1
10 downloads
92 views

Protein sites present different amino acids during their evolution, whose number reflects the selective constraints operating on them. This evolutionary variability is strongly influenced by the structural properties of the site in the native structure, and it...

["Bioinformatics","Biophysics","Computational Biology","Evolutionary Studies"]
doi:10.7287/peerj.preprints.26868v1
71 downloads
194 views

Single-cell RNA-seq is revolutionizing our understanding of cell type heterogeneity in many fields of biology, ranging from neuroscience to cancer to immunology. In Immunology, one of the main promises of this approach is the ability to define cell types as clusters...

["Bioinformatics","Computational Biology","Evolutionary Studies","Immunology"]
doi:10.7287/peerj.preprints.26858v1
35 downloads
84 views

Since 2014 divers from Ocean Wise have been SCUBA diving in the Cambridge Bay, Nunavut area collecting data on fishes, invertebrates and marine plants at numerous sites. For each dive a file is created that catalogues the species found and a rough abundance of...

["Bioinformatics","Ecology","Marine Biology","Taxonomy"]
doi:10.7287/peerj.preprints.26850v1
128 downloads
365 views

Many data include time or have longitudinal dimensionalilty. When these data include an index of time, i.e. measures at regular or periodically successive intervals, statistics that use time sequencing in some capacity are appropriate. Consequently, investing time...

["Bioinformatics","Computational Biology","Data Science"]
doi:10.7287/peerj.preprints.26842v1
36 downloads
109 views

Acquiring data on the occurrences of many types of difficult to identify objects are often still made by human observation, e.g. in biodiversity and paleontologic research. Existing computer counting programs used to record such data have various limitations, including...

["Biodiversity","Bioinformatics","Ecology","Paleontology"]
doi:10.7287/peerj.preprints.26836v1
94 downloads
347 views

Next-generation sequencing has provided powerful tools to conduct microbial ecology studies. Analysis of community composition relies on annotated databases of curated sequences to provide taxonomic assignments; however, these databases occasionally have errors...

["Bioinformatics","Ecology","Marine Biology","Microbiology","Taxonomy"]
doi:10.7287/peerj.preprints.26824v1
223 downloads
397 views
Christos D Arvanitidis, Richard M Warwick, Paul J Somerfield, Christina Pavloudi, Evangelos Pafilis, Anastassis Oulas, Giorgos Chatzigeorgiou, Vasilis Gerovasileiou, Theodoros Patkos, Nicolas Bailly, Francisco Hernandez, Bart Vanhoorne, Leen Vandepitte, Ward Appeltans, Robert Adlard, Peter Adriaens, Ahn Kee-Jeong, Ahyong Shane, Akkari Nesrine, Gary Anderson, Angel Martin, Claudia Arango, Tom Artois, Stephen Atkinson, Ruud Bank, Anthony D Barber, Joao P Barbosa, Ilse Bartsch, Denise Bellan-Santini, Jimmy Bernot, Annalisa Berta, Rüdiger Bieler, Magda Błażewicz, Phil Bock, Ruth Böttger-Schnack, Philippe Bouchet, Nicole Boury-Esnault, Geoff Boxshall, Christopher B Boyko, Simone Nunes Brandão, Rod Bray, Niel L Bruce, Stephen Cairns, Tania N Campinas Bezerra, Paco Cárdenas, Benny KK Chan, Tin-Yam Chan, Lanna Cheng, Morgan Churchill, Laure Corbari, Ralf Cordeiro, Astrid Cornils, Keith A Crandall, Thomas Cribb, Jean-Loup D'hondt, Meg Daly, Mikhail Daneliya, Jean-Claude Dauvin, Peter Davie, Claude De Broyer, Valentin De Mazancourt, Nicole De Voogd, Peter Decker, Danielle Defaye, Henk Dijkstra, Martin Dohrmann, Daryl Domning, Rachel Downey, Inna Drapun, Ursula Eisendle-Flöckner, Christine Ewers-Saucedo, Marien Faber, Diego Figueroa, Julian Finn, Gustavo Fonseca, Ewan Fordyce, William Foster, Hidetaka Furuya, Horia Galea, Oscar Garcia-Alvarez, Rade Garic, Rebeca Gasca, Santiago Gaviria-Melo, Sarah Gerken, David Gibson, João Gil, Arjan Gittenberger, Chris Glasby, Serge Gofas, Samuel E Gómez-Noguera, David González-Solís, Dennis Gordon, Michal Grabowski, Cinzia Gravili, José M Guerra-García, Roberto Guidetti, Katja Guilini, Kerry A Hadfield, Ed Hendrycks, Bachiller Herrera, Ju-Shey Ho, Jens Høeg, Oleksandr Holovachov, Matthew D Hooge, John Hooper, Tammy Horton, Lauren Hughes, Matús Hyžný, Luiz IF Moretti, Tohru Iseto, Viatcheslav N Ivanenko, Gerhard Jarms, Damià Jaume, Krzysztof Jazdzewski, Ivana Karanovic, Young-Hyo Kim, Rachael King, Michelle Klautau, Jürgen Kolb, Alexey Kotov, Traudl Krapp-Schickel, Antonina Kremenetskaia, Reinhardt Kristensen, Andreas Kroh, Sven Kullander, Rafael La Perna, Sara LeCroy, Daniel Leduc, Rafael Lemaitre, Anne-Nina Lörz, Jim Lowry, Enrique Macpherson, Larry Madin, Tomasz Mamos, Renata Manconi, Bruce Marshall, David J Marshall, Patrick Martin, Sandra McInnes, Jan Mees, Tõnu Meidla, Kelly Merrin, Dmitry Miljutin, Claudia Mills, Vadim Mokievsky, Tina Molodtsova, Rich Mooi, André C Morandini, Rosana Moreira Da Rocha, Fabio Moretzsohn, Jonas Mortelmans, Jeanne Mortimer, Luigi Musco, Thomas A Neubauer, Eike Neubert, Peter NG Neuhaus, Anh D Nguyen, Claus Nielsen, Jon Norenburg, Tim O'Hara, Hisayo Okahashi, Dennis Opresko, Masayuki Osawa, Yuzo Ota, Gustav Paulay, Vincent Perrier, William Perrin, Iorgu Petrescu, Bernard Picton, John F Pilger, Andrzej Pisera, Dan Polhemus, Gary Poore, James D Reimer, Hans Reip, Michael Reuscher, Pilar Rios Lopez, Marc Rius, Klaus Rützler, Alexander Rzhavsky, José Saiz-Salinas, André F Sartori, Heinrich Schatz, Bernd Schierwater, Andreas Schmidt-Rhaesa, Simon Schneider, Christine Schönberg, André R Senna, Cristiana Serejo, Shabuddin Shaik, Shokoofeh Shamsi, Jyotsna Sharma, Noa Shenkar, Andrew Shinn, Jacek Sicinski, Volker Siegel, Petra Sierwald, Elizabeth Simmons, Frederic Sinniger, Duncan Sivell, Boris Sket, Harry Smit, Nicole Smol, Jesser F Souza-Filho, Jörg Spelda, Sérgio N Stampar, Eric Stienen, Pavel Stoev, Sabine Stöhr, Malin Strand, Eduardo Suárez-Morales, Mindi Summers, Billie J Swalla, Stefano Taiti, Masaatsu Tanaka, Anne H Tandberg, Danny Tang, Mark Tasker, Harry ten Hove, Jan J ter Poorten, Jim Thomas, Erik V Thuesen, Mike Thurston, Ben Thuy, Juan T Timi, Antonio Todaro, Xavier Turon, Peter Uetz, Sergiy Utevsky, Jean Vacelet, Risto Väinölä, Sancia ET van der Meij, Ton van Haaren, Virág Venekey, Chris Vos, Genefor Walker-Smith, Chad T Walter, Les Watling, Matthew Wayland, Christopher Whipps, Gary Williams, Robin Wilson, Moriaki Yasuhara, Joana Zanol, Wolfgang Zeidler

Research Infrastructures (RIs) are facilities, resources and services used by the scientific community to conduct research and foster innovation. LifeWatch ERIC has developed various virtual research environments, which include many virtual laboratories (vLabs)...

["Biodiversity","Bioinformatics","Marine Biology","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.26819v1
29 downloads
190 views

We present PromoterPredict, a dynamic multiple regression approach to predict the strength of Escherichia coli promoters binding the σ70 factor of RNA polymerase. σ70 promoters are ubiquitously used in recombinant DNA technology, but characterizing their strength...

["Bioengineering","Bioinformatics","Biotechnology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26759v2
128 downloads
280 views

High-throughput sequencing of environmental DNA (eDNA) offers a simple and cost-effective solution for marine biodiversity assessments. Yet several analytical challenges remain, including the incorporation of statistical inference in the assignment of taxonomic...

["Biodiversity","Bioinformatics","Computational Biology","Marine Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26812v1
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