Preprints (not yet peer-reviewed)

68 downloads
218 views

CodonGenie, freely available from http://codon.synbiochem.co.uk, is a simple web application for designing ambiguous codons to support protein mutagenesis applications. Ambiguous codons are derived from specific heterogeneous nucleotide mixtures, which create sequence...

["Bioengineering","Bioinformatics","Biotechnology","Computational Biology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2797v1
960 downloads
694 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6
155 downloads
313 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
114 downloads
216 views

Synthetic biology is often misunderstood as creation of artificial life or new biology using principles different from those of extant organisms around us. But, fundamentally, the field is about engineering biology in a more efficient and effective way, and endowing...

["Biochemistry","Bioengineering","Biotechnology","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.2634v1
70 downloads
376 views

Background: Cryoelectrolysis is a new minimally invasive tissue ablation surgical technique that combines the ablation techniques of electrolytic ablation with cryosurgery. The goal of this study is to examine the hypothesis that electrolysis can take place in...

["Bioengineering","Biophysics","Oncology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2474v2
147 downloads
201 views

We report the development and characterization of 13 novel microsatellite loci for the Caribbean queen conch, Lobatus gigas, an ecologically and commercially important marine gastropod. Paired-end sequencing was carried out on genomic DNA from a single queen conch...

["Bioengineering","Bioinformatics","Conservation Biology","Genetics","Genomics"]
doi:10.7287/peerj.preprints.2559v1
183 downloads
537 views

For this initial work, we shall focus on introducing a biological model for utilization [mainly] as a descriptive framework on which future analyses will be based. The model includes a definition of a biological system as a composite of properties that occupy defined...

["Bioengineering","Computational Biology","Mathematical Biology"]
doi:10.7287/peerj.preprints.1148v4
151 downloads
185 views

Background: Electrolytic ablation and electroporation based ablation are minimally invasive, non-thermal surgical technologies that employ electrical currents and electric fields to ablate undesirable cells in a volume of tissue. In this study we explore the attributes...

["Bioengineering","Biophysics","Oncology","Pathology","Histology"]
doi:10.7287/peerj.preprints.2549v1
1,563 downloads
3,117 views

3D printers that build objects using extruded thermoplastic are quickly becoming common place tools in laboratories. We demonstrate that with appropriate handling, these devices are capable of producing sterile components from a non-sterile feedstock of thermoplastic...

["Bioengineering","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.542v2
174 downloads
351 views

Increasingly complex data sets are needed to fully understand the complexity in behavior. Credit card sized single-board computers with multi-core CPUs are an attractive platform for designing devices capable of collecting multi-dimensional behavioral data. To...

["Animal Behavior","Bioengineering","Neuroscience"]
doi:10.7287/peerj.preprints.2435v1
111 downloads
268 views

Nitrite-dependent anaerobic methane oxidation (n-damo) is a recently discovered biological process, which has been arousing global attention because of its potential in minimizing greenhouse gases emissions. In this study, molecular biological techniques and potential...

["Agricultural Science","Bioengineering","Environmental Sciences","Soil Science"]
doi:10.7287/peerj.preprints.2421v1
55 downloads
330 views

Development of new techniques and appropriate equipment for treatment of long bone fractures in bovines has been an objective of recent veterinary research. Accurate estimates of body segment inertial parameters (BSIP) are essential for determination of forces...

["Animal Behavior","Bioengineering","Veterinary Medicine"]
doi:10.7287/peerj.preprints.2395v1
105 downloads
396 views

The ostrich is a highly cursorial bipedal land animal with a permanently elevated metatarsophalangeal joint supported by only two toes. Although locomotor kinematics in walking and running ostriches have been examined, these studies have been largely limited to...

["Animal Behavior","Bioengineering","Anatomy and Physiology","Kinesiology"]
doi:10.7287/peerj.preprints.2324v1
371 downloads
680 views

Challenging disposal problems are associated with plastics use due to its poor biodegrability and emissions of hazardous chemicals during incineration. Poly-β-hydroxybutyric acids (PHB), a lipid based storage polymer in bacteria, is biodegradable, biorenewable...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.534v5
40 downloads
269 views

Bacteria surface charge derives its meaning from the cell’s environment; thus, there is no specific surface charge. Determining the surface charge of bacteria in its native environment requires measuring the proxy variable, zeta potential, using cells obtained...

["Bioengineering","Biophysics","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.2086v2
What is a PeerJ Preprint?

A PeerJ Preprint is a draft of an article, abstract, or poster that has not yet been peer-reviewed for formal publication. Submit a draft, incomplete, or final version of your work for free.

Submissions today can be approved by Editorial Staff and online in 24 hours.

Establish precedent. Solicit feedback. Publish updates.

Top subject areas - Preprints

Top subject areas - People

View all subject areas