Preprints (not yet peer-reviewed)

13 downloads
70 views

Intact biomolecules carry its identity through its atomic constituents and mass, while fragmented biomolecules require reconstruction for their identity to be retrieved. Hence, for profiling biomolecules in mixtures, the goal would be the gentle ionization of biomolecules...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.26983v1
63 downloads
162 views

Clustered regularly interspersed short palindromic repeats (CRISPR) is a natural defense system for bacteria and archaea against foreign DNA and RNA. Specifically, short snippets of foreign DNA or RNA are incorporated into protospacer adjacent motif (PAM) repeats...

["Biochemistry","Bioengineering","Biotechnology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26975v1
107 downloads
76 views

LB Lennox medium is commonly used for bacterial cell culture, but the amount of biomass obtained while sufficient for molecular biology and biochemical studies, is insufficient for applied microbiology research. Thus, supplementation of LB Lennox with glucose is...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26949v1
34 downloads
118 views

Coping with nutritional stress is essential for cell survival, of which many strategies at the cellular level lend support for ensuring the survival of the population at a particular habitat. One postulated mechanism is swarming motility in bacterial cells, where,...

["Biochemistry","Bioengineering","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.26914v1
393 downloads
880 views

Many pressing medical challenges -- such as diagnosing disease, enhancing directed stem cell differentiation, and classifying cancers -- have long been hindered by limitations in our ability to quantify proteins in single cells. Mass-spectrometry (MS) is poised...

["Bioengineering","Biotechnology","Cell Biology","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.26821v1
39 downloads
261 views

We present PromoterPredict, a dynamic multiple regression approach to predict the strength of Escherichia coli promoters binding the σ70 factor of RNA polymerase. σ70 promoters are ubiquitously used in recombinant DNA technology, but characterizing their strength...

["Bioengineering","Bioinformatics","Biotechnology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.26759v2
34 downloads
130 views

Polyethylene glycol is commonly used in fermentations as an anti-foam for preventing the rise of foam to the top plate of the bioreactor, which increases contamination risk. However, its potential toxicity to growth of various microorganisms is not well understood...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26817v1
48 downloads
231 views

Background. Entolimod is a Salmonella enterica flagellin derivate. Previous work has demonstrated that entolimod effectively protects mice and non-human primates from ionizing radiation. However, it caused a “flu-like” syndrome after radioprotective and anticancer...

["Biochemistry","Bioengineering","Biotechnology"]
doi:10.7287/peerj.preprints.26803v1
47 downloads
143 views

The production of lignocellulosic ethanol is one of the most promising alternatives to fossil fuels, however, this technology still faces many challenges related to the viability of the alcohol in the market. In this paper the endocarp of buriti fruit was assessed...

["Agricultural Science","Bioengineering","Food, Water and Energy Nexus"]
doi:10.7287/peerj.preprints.26777v1
83 downloads
98 views

Background. Brain function requires a coordinated flow of information among functionally specialized areas. Quantitative methods provide a multitude of metrics to quantify the oscillatory interactions measured by invasive or non-invasive recording techniques. Granger...

["Bioengineering","Neuroscience"]
doi:10.7287/peerj.preprints.26703v1
50 downloads
99 views

Currently, a variety of display technologies have been developed in the life science field, such as phage display, ribosome display, and yeast display. Many studies have found that display technologies are powerful and universal methods when they are combined with...

["Bioengineering","Biotechnology","Molecular Biology"]
doi:10.7287/peerj.preprints.26702v1
125 downloads
208 views

Jasmonic acid (JA) and its derivatives (called jasmonates) are lipid-derived signalling molecules that are produced by certain bacteria, fungi and plants. Beside this function, jasmonates have a great variety of applications in the flavour and fragrances production....

["Agricultural Science","Biochemistry","Bioengineering","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.26655v1
52 downloads
158 views

Bacterial cell surface carries an electrical charge due to the myriad functional groups present, as well as assortment of ions and molecules nonspecifically adsorbed to the cell surface. Thus, solution in contact with the bacterial cell surface play a critical...

["Biochemistry","Bioengineering","Biotechnology","Microbiology","Biogeochemistry"]
doi:10.7287/peerj.preprints.26626v1
55 downloads
187 views

Cell quantification assays are essential components of most biological and clinical labs. However, many currently available quantification assays, including flow cytometry and commercial cell counting systems, suffer from unique drawbacks that limit their overall...

["Bioengineering","Biotechnology"]
doi:10.7287/peerj.preprints.26584v1
49 downloads
182 views

High cell density cultivation necessitates cell division and biomass formation, the mechanisms of which remain poorly understood, especially from the cellular energetics perspective. Specifically, the sensing of energy abundance and the channelling of nutritional...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Microbiology"]
doi:10.7287/peerj.preprints.26598v1
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