Preprints (not yet peer-reviewed)

Understanding how structural and functional alterations of individual tissues impact on whole-joint function is challenging, particularly in humans where direct invasive experimentation is difficult. Finite element computational models produce quantitative predictions...

["Bioengineering","Biotechnology","Computational Biology"]
doi:10.7287/peerj.preprints.3050v1
7 downloads
64 views

Many difficulties are encountered by people with disabilities, especially when a diagnosis is made up of more than one dysfunction, as is the case of visually impaired wheelchair users. In fact, this scenario generates a degree of incapacity in terms of the performing...

["Bioengineering","Bioinformatics","Neuroscience","Clinical Trials","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.3036v1
241 downloads
561 views

Microbes for environmental research should be cultured in growth media with characteristics (e.g., pH, ionic strength, and ionic composition) as close to their original habitat as possible. Additionally, the medium should also enable high cell density to be obtained,...

["Biochemistry","Bioengineering","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.1406v5
1,009 downloads
1,814 views

Zeta potential, defined as the electric charge at the shear plane, is widely used as a proxy parameter for bacterial cell surface charge. Nonspecific adsorption of ions or polyelectrolytes onto the cell surface, however, alters the value and polarity of the measured...

["Bioengineering","Biophysics","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.110v6
189 downloads
867 views

Solid medium enables spatially resolved simultaneous cultivation of different microbes in a simple and relatively low cost format useful for preliminary screening of microbial diversity. Lack of color contrast between colonies and agar, however, hampers colony...

["Biochemistry","Bioengineering","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.89v5
181 downloads
822 views

The characteristics of the culture vessel determine, to a large extent, the type of growth medium suitable for use. For example, most growth media for high cell density cultivation are designed for expensive bioreactors operating either in continuous or fed-batch...

["Biochemistry","Bioengineering","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.117v5
31 downloads
144 views

We investigated the structure and properties of PCL10 nanofiber, PCL5/PCL10 core-shell type nanofibers, as well as PCL5/PCLAg nanofibres prepared by electrospinning. For the production of the fibre variants, a 5-10% solution of polycaprolactone (Mw = 70000-90000),...

["Bioengineering","Biotechnology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2971v1
102 downloads
1,047 views

Background. The goals of this study were (1) to present the set of data evaluating running biomechanics (kinematics and kinetics), including data on running habits, demographics, and levels of muscle strength and flexibility made available at Figshare (DOI: 10.6084/m9.figshare.4543435);...

["Bioengineering","Neuroscience","Kinesiology","Computational Science"]
doi:10.7287/peerj.preprints.2888v1
30 downloads
340 views

This article describes a public data set with the three-dimensional kinematics of the whole body and the ground reaction forces (with a dual force platform setup) of subjects standing still for 60 s in different conditions, in which the vision and the standing...

["Bioengineering","Neuroscience","Kinesiology"]
doi:10.7287/peerj.preprints.2865v1
863 downloads
777 views

The past influences the present and future; for example, in computational chemistry, simplifying assumptions and approximations important in the pre-computing era remains relevant today in allowing simulation of larger systems with reasonable amount of computer...

["Biochemistry","Bioengineering","Biophysics","Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.365v4
54 downloads
146 views

CodonGenie, freely available from http://codon.synbiochem.co.uk, is a simple web application for designing ambiguous codons to support protein mutagenesis applications. Ambiguous codons are derived from specific heterogeneous nucleotide mixtures, which create sequence...

["Bioengineering","Bioinformatics","Biotechnology","Computational Biology","Synthetic Biology"]
doi:10.7287/peerj.preprints.2797v1
843 downloads
618 views

Divergence of treatment responses to chemotherapy exists across patients (often with unknown underlying mechanisms), with some patients exhibiting worsened outcome upon treatment. Genomic approaches (such as microarray profiling and whole genome sequencing) hold...

["Bioengineering","Bioinformatics","Cell Biology","Genomics","Histology"]
doi:10.7287/peerj.preprints.1049v6
94 downloads
262 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
101 downloads
176 views

Synthetic biology is often misunderstood as creation of artificial life or new biology using principles different from those of extant organisms around us. But, fundamentally, the field is about engineering biology in a more efficient and effective way, and endowing...

["Biochemistry","Bioengineering","Biotechnology","Computational Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.2634v1
57 downloads
288 views

Background: Cryoelectrolysis is a new minimally invasive tissue ablation surgical technique that combines the ablation techniques of electrolytic ablation with cryosurgery. The goal of this study is to examine the hypothesis that electrolysis can take place in...

["Bioengineering","Biophysics","Oncology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2474v2
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