Preprints (not yet peer-reviewed)

13 downloads
89 views

Background: Oxidative stress plays an important role in the pathogenesis of heart diseases. Antioxidants such as palm tocotrienol-rich fraction (TRF) can reduce oxidative stress, hence preventing and reducing the risk of heart disease. This study was aimed to determine...

["Biochemistry","Nutrition"]
doi:10.7287/peerj.preprints.3333v1
11 downloads
73 views

Transglutaminases (TGases) are a class of enzyme widely spread in nature, and observed in plants, microorganisms, vertebrates and invertebrates. This enzyme catalyzes post-translational protein modification, by acyl transfer reactions, deamidation and crosslinking...

["Biochemistry","Bioinformatics"]
doi:10.7287/peerj.preprints.3320v1
10 downloads
124 views

Quality disciplines have been widely used for decades in industrial and business fields. It is only in recent times, however, that Quality management and approaches have received proper attention in life science. The development, optimization, validation and dissemination...

["Biochemistry","Cell Biology","Developmental Biology","Ethical Issues","Science Policy"]
doi:10.7287/peerj.preprints.3316v1
117 downloads
1,014 views

The classification of Cannabis varieties has been increasingly discussed in the past years, particularly in the wake of emerging legal markets, with implications for intellectual property development, marketing and improvement of the scientific understanding of...

["Agricultural Science","Biochemistry","Biodiversity","Plant Science","Taxonomy"]
doi:10.7287/peerj.preprints.3307v1
21 downloads
70 views

Scale transcends multiple levels of biological and physical organization, and is the critical factor that determines success of any scientific investigation. Specifically, the scale at which a question is posed plays a crucial role in influencing the type of experiments...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.3261v1
11 downloads
74 views

Microfluidic cell culture chambers have enabled the isolation, culture and growth of various species of microorganisms and human cells. However, based on elastomers such as poly(dimethyl siloxane) (PDMS), these culture devices are not readily amenable to imaging...

["Biochemistry","Bioengineering","Biotechnology","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3245v1
7 downloads
100 views

Co-existence of microbes in a community is the de facto state of microbial lifestyle in almost all niches on Earth. Thus, microbes live with other microbial species in close proximity, and evolution has selected for specific methods of communication between microbes...

["Biochemistry","Biodiversity","Cell Biology","Ecology","Microbiology"]
doi:10.7287/peerj.preprints.3239v1
11 downloads
181 views

Contemporary proteins can be traced back to a basic set of a few thousand domain prototypes. The origin of these domain prototypes, however, remains poorly understood. We have proposed that they arose from an ancestral set of peptides, which acted as cofactors...

["Biochemistry","Bioinformatics","Evolutionary Studies"]
doi:10.7287/peerj.preprints.3234v1
57 downloads
118 views

Single cell studies increasing reveal myriad cellular subtypes beyond those postulated or observed through optical and fluorescence microscopy as well as DNA sequencing studies. While gene sequencing at the single cell level offer a path towards illuminating, in...

["Biochemistry","Biotechnology","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3193v1
61 downloads
161 views

Background. Carrot is a multi-nutritional food source. It is an important root vegetable, rich in natural bioactive compounds with health-promoting properties, such as antioxidants that have anti-carcinogenic properties. Aim. This review summarises the occurrences...

["Agricultural Science","Biochemistry","Food Science and Technology","Plant Science","Nutrition"]
doi:10.7287/peerj.preprints.3187v1
278 downloads
736 views

Microbes for environmental research should be cultured in growth media with characteristics (e.g., pH, ionic strength, and ionic composition) as close to their original habitat as possible. Additionally, the medium should also enable high cell density to be obtained,...

["Biochemistry","Bioengineering","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.1406v6
335 downloads
5,074 views

In 1961, the NIH began to circulate biological preprints in a forgotten experiment called the Information Exchange Groups (IEGs). This system eventually attracted over 3600 participants and saw the production of over 2,500 different documents, but by 1967 it was...

["Biochemistry","Science Policy"]
doi:10.7287/peerj.preprints.3174v1
25 downloads
142 views

Scientific terms should be as accurate and meaningful as possible for both researchers and the general science readership. Currently, some scientific terms do not properly describe the activity or function to which they are associated to, being frequently characterized...

["Biochemistry","Genetics","Genomics","Molecular Biology"]
doi:10.7287/peerj.preprints.3102v1
27 downloads
104 views

Survival of microbes on various surfaces and environment is a question of importance to basic science, as well as health care, water treatment and distribution, ecology, and search for life in other planetary bodies. To this end, various model organisms, known...

["Biochemistry","Biotechnology","Cell Biology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.3103v1
37 downloads
152 views

The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions and the standard...

["Biochemistry","Computational Biology","Mathematical Biology","Drugs and Devices","Pharmacology"]
doi:10.7287/peerj.preprints.3094v1
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