Preprints (not yet peer-reviewed)

130 downloads
283 views

Background. Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. This study aimed to determine the utility of RNA-Seq to call gene sequence variants, and to identify sequence variants or potential...

["Genetics","Veterinary Medicine","Allergy and Clinical Immunology","Respiratory Medicine"]
doi:10.7287/peerj.preprints.3491v2
225 downloads
482 views

Background An adult mare, presented to the University of Tennessee’s Veterinary MedicalCenter because of chronic, persistent coughing and abnormal respiratory noise,was found, during endoscopic examination of its nasopharynx and larynx, to havehypoplasia of the...

["Respiratory Medicine","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.26638v1
166 downloads
269 views

Setting Seven public tuberculosis (TB) units in Kampala, Uganda, where Uganda’s national TB program recently introduced household contact investigation, as recommended by 2012 guidelines from WHO. Objective To apply a cascade analysis to implementation of household...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.3313v1
126 downloads
381 views

To discuss whether there is relationship between short-term and long-time attenuation effects of ventilation caused by diving activity. The ventilation observed before and after hyperbaric exposure for 20min by case-control experiments. Participants of the experimental...

["Respiratory Medicine","Science and Medical Education"]
doi:10.7287/peerj.preprints.3027v2
330 downloads
2,687 views

Objective: In this study the main aspects of influenza transmission via fine and ultrafine bioaerosols were considered. Here, we aimed to estimate the impact of the different environment conditions on the deposition rate of the infectious bioaerosols in the respiratory...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.2237v5
117 downloads
987 views

We have originally shown for the first time the two different climatic patterns of seasonality of influenza and common colds have an only one common “link”. It is the effect of supersaturation and condensational growth in the upper airways which occurs under specific...

["Epidemiology","Global Health","Infectious Diseases","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.2859v2
284 downloads
675 views

Ion mobility spectrometry (IMS) is a technology for the detection of volatile compounds in the air of exhaled breath that is increasingly used in medical applications. One major goal is to classify patients into disease groups, for example diseased versus healthy,...

["Bioinformatics","Respiratory Medicine","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.1294v1
266 downloads
389 views

The metabolic syndrome (MS) affects 21-53% of patients with chronic obstructive pulmonary disease (COPD) with a higher prevalence in the early stages of COPD, with results being highly variable between studies. MS may also correlate with disease characteristics....

["Diabetes and Endocrinology","Epidemiology","Internal Medicine","Respiratory Medicine"]
doi:10.7287/peerj.preprints.1022v1
615 downloads
434 views

Diabetes mellitus (DM) affects 2-37% of patients with chronic obstructive pulmonary disease (COPD), with results being highly variable between studies. DM may also correlate with disease characteristics.The aim of this study was to examine the prevalence of DM...

["Diabetes and Endocrinology","Epidemiology","Internal Medicine","Respiratory Medicine"]
doi:10.7287/peerj.preprints.939v1
170 downloads
381 views

Aims: The purpose of this study was to analyse the bacterial and fungal turnover in the lungs of cystic fibrosis patients who were ΔF508 homo- and hetero-zygotes. Further to this we wanted to identify the effects that Intravenous (IV) antibiotic perturbations had...

["Microbiology","Molecular Biology","Mycology","Respiratory Medicine"]
doi:10.7287/peerj.preprints.637v1
463 downloads
3,920 views

The atmospheric concentration of oxygen, a driver of free radical damage and tumorigenesis, decreases sharply with rising elevation. To understand whether ambient oxygen concentrations play a role in human carcinogenesis, we characterized age-adjusted cancer incidence...

["Epidemiology","Oncology","Public Health","Respiratory Medicine","Statistics"]
doi:10.7287/peerj.preprints.587v2
332 downloads
580 views

Background and objectives: Numerous experimental studies have linked cigarette smoking to lung injury. However, it is still debated on whether cigarette smoking is a risk factor for the development of acute lung injury/acute respiratory distress syndrome (ALI/ARDS)....

["Clinical Trials","Emergency and Critical Care","Evidence Based Medicine","Respiratory Medicine"]
doi:10.7287/peerj.preprints.574v1
429 downloads
1,677 views

Tuberculosis remains a major global health problem. Laboratory diagnostic methods that allow effective, early detection of cases are central to management of tuberculosis in the individual patient and in the community. Since the 1880s, laboratory diagnosis of tuberculosis...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases","Respiratory Medicine"]
doi:10.7287/peerj.preprints.482v1
1,354 downloads
612 views

Background: The thickness and composition of the surface liquid lining the human lungs are maintained by a balance between epithelial secretion and absorption of ions and water. An understanding of epithelial transport pathways and the factors that regulate them...

["Bioengineering","Biophysics","Cell Biology","Molecular Biology","Respiratory Medicine"]
doi:10.7287/peerj.preprints.256v1
3,760 downloads
764 views

Background: In the wake of burgeoning slum population, a substantial reduction in the prevalence of diarrhea and acute respiratory infections (ARI) is necessary for to achieve necessary reduction in child mortality in urban India. To achieve this, we need evidence...

["Epidemiology","Global Health","Health Policy","Public Health","Respiratory Medicine"]
doi:10.7287/peerj.preprints.208v1
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