Preprints (not yet peer-reviewed)

95 downloads
215 views

Objective. In the foveola of the eye, photoreceptors and Müller cells with a unique morphology have been described, but little is known about their 3D structure and orientation. Considering that there is an angle-dependent change in the foveolar photoreceptor response...

["Biophysics","Cell Biology","Anatomy and Physiology","Ophthalmology","Histology"]
doi:10.7287/peerj.preprints.26518v1
108 downloads
259 views

The compound eye is the primary visual system in crustaceans. Although the histological structure and histochemical characteristics of compound eyes of some insect and crab species are now well understood, no such studies have been undertaken in the whiteleg shrimp...

["Aquaculture, Fisheries and Fish Science","Anatomy and Physiology","Ophthalmology","Pathology","Histology"]
doi:10.7287/peerj.preprints.3453v1
135 downloads
432 views

Measurement of visual functions is critical to the detection and diagnosis of eye disease, particularly in children where eliciting symptomology can be challenging. An effective practitioner-patient relationship is crucial in optometric practice and has numerous...

["Ophthalmology","Pediatrics"]
doi:10.7287/peerj.preprints.3023v1
111 downloads
531 views

Previous studies have used the zebrafish to investigate the biology of lens crystallin proteins and their roles in development and disease. However, little is known about zebrafish α-crystallin promoter function, how it compares to that of mammals, or whether mammalian...

["Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7287/peerj.preprints.2889v1
185 downloads
228 views

BACKGROUNDː This article describes the characterization of a new cell line (IRB-1), which was established from an Iranian child with retinoblastoma. METHODSː Using cell culture techniques, we isolated a clonal population from primary Cultures of retinoblastoma...

["Cell Biology","Oncology","Ophthalmology"]
doi:10.7287/peerj.preprints.2780v1
82 downloads
355 views

Purpose: To compare the intraoperative angle stability and the postoperative outflow of two ab interno trabeculectomy devices that excise the trabecular meshwork. The newer device has an active aspiration and irrigation port while the older requires viscoelastic...

["Drugs and Devices","Ophthalmology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2762v2
191 downloads
404 views

Objective: Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed...

["Bioengineering","Ophthalmology","Statistics"]
doi:10.7287/peerj.preprints.2736v3
75 downloads
273 views

Purpose: Microincisional glaucoma surgeons operate in a highly confined space, making it difficult to learn by observation or assistance alone. We hypothesized that an ex vivo model would allow for better refinement of technique, quantification of progress, and...

["Ophthalmology","Surgery and Surgical Specialties"]
doi:10.7287/peerj.preprints.2745v1
482 downloads
857 views

Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, that is, analyzing...

["Neuroscience","Ophthalmology","Psychiatry and Psychology","Statistics"]
doi:10.7287/peerj.preprints.2725v1
44 downloads
322 views

Background. Opacities of the lens are typical age related phenomena which have high influence on photoreception and consequently circadian rhythm. In mouse lemurs, a small bodied non-human primate, a high incidence (more than 50% when > 7 years) of cataract has...

["Veterinary Medicine","Ophthalmology"]
doi:10.7287/peerj.preprints.2714v1
123 downloads
589 views

Aim/hypothesis The aim of our study was to characterize the human salivary proteome and determine the changes in protein expression in 2 different stages of diabetic retinopathy with type-2 diabetes mellitus: (1) with non-proliferative diabetic retinopathy (NPDR)...

["Biochemistry","Diabetes and Endocrinology","Ophthalmology"]
doi:10.7287/peerj.preprints.1973v1
494 downloads
689 views

Contact with and handling of burs (the flowering heads or infructescences) from the greater burdock (Arctium lappa L., Asteraceae) and other members of the same genus, is a potential hazard for humans, horses, and dogs. The minute, sharply-pointed, bristly pappus...

["Agricultural Science","Veterinary Medicine","Ophthalmology","Public Health","Science and Medical Education"]
doi:10.7287/peerj.preprints.1871v1
97 downloads
488 views

Introduction: The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, a series of cognitive tests as potentially...

["Epidemiology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.738v2
429 downloads
486 views

INTRODUCTION: Diabetic retinopathy affects majority (70% to 90%) of diabetic patients, causes visual impairment which leads to severe psycho-social disruption in life. Our objective was to study the patients of diabetic retinopathy, co-relate between the types...

["Diabetes and Endocrinology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.981v1
162 downloads
245 views

Background: Blindness and severe visual impairment render affected individuals, families and communities economically, socially and physically disadvantaged. The number of adults ≥ 40 years with severe visual impairment and blindness in Nigeria is projected to...

["Health Policy","Ophthalmology","Public Health"]
doi:10.7287/peerj.preprints.974v1
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